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2HA8
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Methyltransferase Domain of Human TAR (HIV-1) RNA binding protein 1
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, TAR (HIV-1) RNA loop binding protein
著者Min, J, Wu, H, Zeng, H, Loppnau, P, Battaile, K, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-06-12
公開日2006-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Crystal Structure of Methyltransferase Domain of Human TAR (HIV-1) RNA binding protein 1 in complex with S-adenosyl-L-homocystein.
To be Published
2H00
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BU of 2h00 by Molmil
Human methyltransferase 10 domain containing protein
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Min, J.R, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-05-12
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Human methyltransferase 10 domain containing protein.
To be Published
2HUZ
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BU of 2huz by Molmil
Crystal structure of GNPNAT1
分子名称: Glucosamine 6-phosphate N-acetyltransferase
著者Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-07-27
公開日2006-08-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structure of glucosamine-phosphate N-acetyltransferase 1
To be Published
2I62
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BU of 2i62 by Molmil
Mouse Nicotinamide N-methyltransferase
分子名称: Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-08-27
公開日2006-09-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of Mouse Nicotinamide N-methyltransferase in complex with SAH
To be Published
2IPX
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BU of 2ipx by Molmil
Human Fibrillarin
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, CALCIUM ION, rRNA 2'-O-methyltransferase fibrillarin
著者Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-10-12
公開日2006-10-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The Crystal Structure of Human Fibrillarin in complex with SAH
To be Published
2IIP
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BU of 2iip by Molmil
Human Nicotinamide N-methyltransferase
分子名称: Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Bernstein, G, Min, J, Wu, H, Tempel, W, Zeng, H, Loppnau, P, Avvakumov, G.V, Wasney, G, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-09-28
公開日2006-10-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Crystal Structure of Human Nicotinamide N-methyltransferase in complex with SAH
To be Published
5E8R
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BU of 5e8r by Molmil
Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae)
分子名称: CHLORIDE ION, N-methyl-N-({4-[4-(propan-2-yloxy)phenyl]-1H-pyrrol-3-yl}methyl)ethane-1,2-diamine, Protein arginine N-methyltransferase 6, ...
著者DONG, A, ZENG, H, LIU, J, TEMPEL, W, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, JIN, J, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
登録日2015-10-14
公開日2015-12-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases.
Acs Chem.Biol., 11, 2016
8JYW
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BU of 8jyw by Molmil
Cryo-EM structure of the gasdermin pore from Trichoplax adhaerens
分子名称: Gasdermin pore forming domain-containing protein
著者Hou, Y.J, Sun, Q, Zeng, H, Ding, J.
登録日2023-07-04
公開日2024-05-01
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8GCY
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BU of 8gcy by Molmil
Co-crystal structure of CBL-B in complex with N-Aryl isoindolin-1-one inhibitor
分子名称: 1,2-ETHANEDIOL, 2-{3-[(1s,3R)-3-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl]phenyl}-6-{[(3S)-3-methylpiperidin-1-yl]methyl}-4-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one, E3 ubiquitin-protein ligase CBL-B, ...
著者Kimani, S, Zeng, H, Dong, A, Li, Y, Santhakumar, V, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
登録日2023-03-03
公開日2023-03-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition.
Commun Biol, 6, 2023
7W1Q
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BU of 7w1q by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase mutant E82Q complexed with 2'-O-methylguanosine
分子名称: Guanosine deaminase, O2'-METHYLGUANOSINE-5'-MONOPHOSPHATE, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2021-11-19
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies.
Int J Mol Sci, 23, 2022
7DCA
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BU of 7dca by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase bound by xanthosine
分子名称: 2,3-dihydroxanthosine, Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-10-23
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The C-terminal loop of Arabidopsis thaliana guanosine deaminase is essential to catalysis.
Chem.Commun.(Camb.), 57, 2021
7DBF
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BU of 7dbf by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase
分子名称: Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-10-20
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The C-terminal loop of Arabidopsis thaliana guanosine deaminase is essential to catalysis.
Chem.Commun.(Camb.), 57, 2021
7DC9
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BU of 7dc9 by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase mutant E82Q complex with guanosine
分子名称: GUANOSINE, Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-10-23
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The C-terminal loop of Arabidopsis thaliana guanosine deaminase is essential to catalysis.
Chem.Commun.(Camb.), 57, 2021
7DCB
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BU of 7dcb by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase complexed with inosine
分子名称: Guanosine deaminase, INOSINE, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-10-23
公開日2021-10-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies.
Int J Mol Sci, 23, 2022
7DCW
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BU of 7dcw by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase complexed with adenosine
分子名称: ADENOSINE, Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-10-27
公開日2021-10-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies.
Int J Mol Sci, 23, 2022
7DH1
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BU of 7dh1 by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase in reaction with N2-Methylguanosine
分子名称: 2,3-dihydroxanthosine, Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-11-12
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies.
Int J Mol Sci, 23, 2022
7DGC
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BU of 7dgc by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase in reaction with 2'-O-Methylguanosine
分子名称: 9-[(2R,3R,4R)-5-(hydroxymethyl)-3-methoxy-4-oxidanyl-oxolan-2-yl]-3H-purine-2,6-dione, Guanosine deaminase, SODIUM ION, ...
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-11-11
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies.
Int J Mol Sci, 23, 2022
7DM6
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BU of 7dm6 by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase complexed with crotonoside
分子名称: 6-azanyl-9-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1H-purin-2-one, Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-12-02
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies.
Int J Mol Sci, 23, 2022
7DM5
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BU of 7dm5 by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase in reaction with guanosine
分子名称: 2,3-dihydroxanthosine, Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-12-02
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies.
Int J Mol Sci, 23, 2022
7DQN
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BU of 7dqn by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase mutant Y185F complexed with guanosine
分子名称: GUANOSINE, Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-12-24
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies.
Int J Mol Sci, 23, 2022
6L6S
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BU of 6l6s by Molmil
The structure of the UdgX mutant H109E crosslinked to single-stranded DNA
分子名称: DNA (5'-D(P*TP*GP*(ORP)P*AP*GP*GP*CP*AP*TP*GP*C)-3'), IRON/SULFUR CLUSTER, Phage SPO1 DNA polymerase-related protein
著者Xie, W, Tu, J, Zeng, H.
登録日2019-10-29
公開日2020-11-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.06425953 Å)
主引用文献Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
6L5B
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The structure of the UdgX mutant H109E at a post-excision state
分子名称: IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein
著者Xie, W, Tu, J, Zeng, H.
登録日2019-10-22
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.00004983 Å)
主引用文献Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
6L5A
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BU of 6l5a by Molmil
The structure of the UdgX mutant H109E at a pre-excision state
分子名称: GLYCEROL, IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein
著者Xie, W, Tu, J, Zeng, H.
登録日2019-10-22
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.80007327 Å)
主引用文献Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
6N31
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WD repeats of human WDR12
分子名称: Ribosome biogenesis protein WDR12, UNKNOWN ATOM OR ION
著者Halabelian, L, Zeng, H, Tempel, W, Li, Y, Seitova, A, Hutchinson, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2018-11-14
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献WD repeats of human WDR12
To Be Published
7WR1
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P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain
分子名称: Caspase-4, OspC3
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-05-29に公開中

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