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4ZNQ
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BU of 4znq by Molmil
Crystal structure of Dln1 complexed with Man(alpha1-2)Man
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Jia, N, Jiang, Y.L, Cheng, W, Wang, H.W, Zhou, C.Z, Chen, Y.
登録日2015-05-05
公開日2016-01-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
4ZNO
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BU of 4zno by Molmil
Crystal structure of Dln1 complexed with sucrose
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Natterin-like protein, ...
著者Jia, N, Jiang, Y.L, Cheng, W, Wang, H.W, Zhou, C.Z, Chen, Y.
登録日2015-05-05
公開日2016-01-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
4ZNR
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BU of 4znr by Molmil
Crystal structure of Dln1 complexed with Man(alpha1-3)Man
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Jia, N, Jiang, Y.L, Cheng, W, Wang, H.W, Zhou, C.Z, Chen, Y.
登録日2015-05-05
公開日2016-01-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
4U8C
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BU of 4u8c by Molmil
Crystal structure of D(CGCGAATTCGCG)2 complexed with BPH-1409
分子名称: 2,2'-benzene-1,4-diylbis[6-(1,4,5,6-tetrahydropyrimidin-2-yl)-1H-indole], DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Zhu, W, Oldfield, E.
登録日2014-08-01
公開日2015-02-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Antibacterial drug leads: DNA and enzyme multitargeting.
J.Med.Chem., 58, 2015
4U8B
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BU of 4u8b by Molmil
Crystal structure of D(CGCGAATTCGCG)2 complexed with BPH-1358
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, N,N'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]biphenyl-4,4'-dicarboxamide
著者Zhu, W, Oldfield, E.
登録日2014-08-01
公開日2015-02-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Antibacterial drug leads: DNA and enzyme multitargeting.
J.Med.Chem., 58, 2015
4U8A
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BU of 4u8a by Molmil
Crystal structure of D(CGCGAATTCGCG)2 complexed with BPH-1503
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, N,N'-bis[3-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]biphenyl-4,4'-dicarboxamide
著者Zhu, W, Oldfield, E.
登録日2014-08-01
公開日2015-02-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Antibacterial drug leads: DNA and enzyme multitargeting.
J.Med.Chem., 58, 2015
4U82
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BU of 4u82 by Molmil
Structure of S. aureus undecaprenyl diphosphate synthase in complex with FSPP and sulfate
分子名称: Isoprenyl transferase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ...
著者Zhu, W, Oldfield, E.
登録日2014-07-31
公開日2015-02-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Antibacterial drug leads: DNA and enzyme multitargeting.
J.Med.Chem., 58, 2015
5C90
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BU of 5c90 by Molmil
Staphylococcus aureus ClpP mutant - Y63A
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit
著者Ye, F, Liu, H, Zhang, J, Gan, J, Yang, C.-G.
登録日2015-06-26
公開日2016-05-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Characterization of Gain-of-Function Mutant Provides New Insights into ClpP Structure
Acs Chem.Biol., 11, 2016
5DI0
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BU of 5di0 by Molmil
Crystal structure of Dln1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Jia, N, Jiang, Y.L, Cheng, W, Wang, H.W, Zhou, C.Z, Chen, Y.
登録日2015-08-31
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
3D8X
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BU of 3d8x by Molmil
Crystal Structure of Saccharomyces cerevisiae NDPPH Dependent Thioredoxin Reductase 1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 1
著者Zhang, Z.Y, Bao, R, Yu, J, Chen, Y.X, Zhou, C.-Z.
登録日2008-05-26
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae cytoplasmic thioredoxin reductase Trr1 reveals the structural basis for species-specific recognition of thioredoxin
Biochim.Biophys.Acta, 1794, 2009
8W6B
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BU of 8w6b by Molmil
crystal structure of TAX1BP1 SKICH domain in complex with RB1CC1 coiled-coil domain
分子名称: RB1-inducible coiled-coil protein 1, Tax1-binding protein 1
著者Zhang, M.F, Pan, L.F.
登録日2023-08-28
公開日2024-07-10
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Mechanistic insights into the interactions of TAX1BP1 with RB1CC1 and mammalian ATG8 family proteins.
Proc.Natl.Acad.Sci.USA, 121, 2024
8W6A
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BU of 8w6a by Molmil
Crystal structure of TAX1BP1 LIR region in complex with GABARAP
分子名称: Gamma-aminobutyric acid receptor-associated protein, Tax1-binding protein 1
著者Zhang, M.F, Pan, L.F.
登録日2023-08-28
公開日2024-07-10
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Mechanistic insights into the interactions of TAX1BP1 with RB1CC1 and mammalian ATG8 family proteins.
Proc.Natl.Acad.Sci.USA, 121, 2024
5C9C
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BU of 5c9c by Molmil
CRYSTAL STRUCTURE OF BRAF(V600E) IN COMPLEX WITH LY3009120 COMPND
分子名称: 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea, CHLORIDE ION, Serine/threonine-protein kinase B-raf
著者Edwards, T, Abendroth, J, Chun, L.
登録日2015-06-26
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.
Cancer Cell, 28, 2015
6IR1
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BU of 6ir1 by Molmil
Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM4 at 1.9 Angstron resolution
分子名称: MCherry fluorescent protein, mCherry's nanobody LaM4
著者Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X.
登録日2018-11-09
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.919 Å)
主引用文献Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry.
Protein Sci., 30, 2021
3D9H
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BU of 3d9h by Molmil
Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein
分子名称: cDNA FLJ77766, highly similar to Homo sapiens ankyrin repeat and SOCS box-containing 9 (ASB9), transcript variant 2, ...
著者Fei, X, Gu, X, Fan, S, Zhang, C, Ji, C.
登録日2008-05-27
公開日2009-06-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein
To be published
5K9J
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BU of 5k9j by Molmil
Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 isolated following H5 immunization.
分子名称: 56.a.09 heavy chain, 56.a.09 light chain, POLYETHYLENE GLYCOL (N=34)
著者Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D.
登録日2016-05-31
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
5H21
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BU of 5h21 by Molmil
Trimethoxy-ring inhibitor in complex with the first bromodomain of BRD4
分子名称: 3,4,5-trimethoxy-~{N}-(2-thiophen-2-ylethyl)benzamide, Bromodomain-containing protein 4
著者Zhang, H, Luo, C.
登録日2016-10-13
公開日2017-07-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.591 Å)
主引用文献Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay.
Medchemcomm, 8, 2017
5KD0
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BU of 5kd0 by Molmil
Crystal structure of the aromatic prenyltransferase AtaPT(E91A) mutant from Aspergillus terreus A8-4 in complex with geranyl S-thiolodiphosphate and (+)-butyrolactone II
分子名称: GERANYL S-THIOLODIPHOSPHATE, aromatic prenyltransferase, methyl (2~{R})-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-4-oxidanyl-5-oxidanylidene-furan-2-carboxylate
著者Sun, F, Gao, B.
登録日2016-06-07
公開日2016-12-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase.
Nat. Chem. Biol., 13, 2017
4W5S
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BU of 4w5s by Molmil
Tankyrase in complex with compound
分子名称: 8-(hydroxymethyl)-2-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]quinazolin-4(3H)-one, GLYCEROL, Tankyrase-1, ...
著者Johannes, J, Kazmirski, S.L, Boriack-Sjodin, P.A, Howard, T.
登録日2014-08-18
公開日2015-05-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology.
Acs Med.Chem.Lett., 6, 2015
5KD6
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BU of 5kd6 by Molmil
Crystal structure of the aromatic prenyltransferase AtaPT from Aspergillus terreus A8-4 in complex with dimethylallyl S-thiolodiphosphate and (-)-butyrolactone II
分子名称: DIMETHYLALLYL S-THIOLODIPHOSPHATE, aromatic prenyltransferase, methyl (2S)-4-hydroxy-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-5-oxo-2,5-dihydrofuran-2-carboxylate
著者Sun, F, Gao, B.
登録日2016-06-07
公開日2016-12-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase.
Nat. Chem. Biol., 13, 2017
5KCG
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BU of 5kcg by Molmil
Crystal structure of the aromatic prenyltransferase AtaPT (apo state) from Aspergillus terreus A8-4
分子名称: aromatic prenyltransferase
著者Sun, F, Gao, B.
登録日2016-06-06
公開日2016-12-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase.
Nat. Chem. Biol., 13, 2017
6D45
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BU of 6d45 by Molmil
L89S Mutant of FeBMb Sperm Whale Myoglobin
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Bhagi-Damodaran, A, Mirts, E.N, Sandoval, B, Lu, Y.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.779 Å)
主引用文献Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5AZC
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BU of 5azc by Molmil
Crystal structure of Escherichia coli Lgt in complex with phosphatidylglycerol
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Prolipoprotein diacylglyceryl transferase
著者Zhang, X.C, Mao, G, Zhao, Y.
登録日2015-09-30
公開日2016-01-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Crystal structure of E. coli lipoprotein diacylglyceryl transferase
Nat Commun, 7, 2016
5AZB
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BU of 5azb by Molmil
Crystal structure of Escherichia coli Lgt in complex with phosphatidylglycerol and the inhibitor palmitic acid
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PALMITIC ACID, Prolipoprotein diacylglyceryl transferase, ...
著者Zhang, X.C, Mao, G, Zhao, Y.
登録日2015-09-30
公開日2016-01-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of E. coli lipoprotein diacylglyceryl transferase
Nat Commun, 7, 2016
6IV0
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BU of 6iv0 by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation I180A
分子名称: Bestrophin homolog, ZINC ION
著者Kittredge, A, Chen, S, Yang, T.
登録日2018-12-02
公開日2019-11-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019

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