8AQ2
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![BU of 8aq2 by Molmil](/molmil-images/mine/8aq2) | In meso structure of the membrane integral lipoprotein N-acyltransferase Lnt from P. aeruginosa covalently linked with TITC | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apolipoprotein N-acyltransferase, CITRATE ANION, ... | 著者 | Huang, C.-Y, Weichert, D, Boland, C, Smithers, L, Olieric, V, Wang, M, Caffrey, M. | 登録日 | 2022-08-11 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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6B8G
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![BU of 6b8g by Molmil](/molmil-images/mine/6b8g) | Twice-Contracted Human Heavy-Chain Ferritin Crystal-Hydrogel Hybrid | 分子名称: | CALCIUM ION, FE (III) ION, Ferritin heavy chain | 著者 | Zhang, L, Bailey, J.B, Subramanian, R, Tezcan, F.A. | 登録日 | 2017-10-07 | 公開日 | 2018-05-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks. Nature, 557, 2018
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5QGS
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![BU of 5qgs by Molmil](/molmil-images/mine/5qgs) | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with FMOPL000476a | 分子名称: | ACETATE ION, DIMETHYL SULFOXIDE, N-(4-chlorophenyl)-N'-[(2R)-1-hydroxybutan-2-yl]urea, ... | 著者 | Krojer, T, Talon, R, Fairhead, M, Diaz Saez, L, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Ruda, G.F, Szommer, T, Srikannathasan, V, Elkins, J, Spencer, J, London, N, Nelson, A, Brennan, P.E, Huber, K, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | 登録日 | 2018-05-15 | 公開日 | 2019-03-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
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8AZZ
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![BU of 8azz by Molmil](/molmil-images/mine/8azz) | KRAS-G12V in complex with BI-2865 | 分子名称: | (4S)-2-azanyl-4-methyl-4-[3-[4-[(1S)-1-[(2S)-1-methylpyrrolidin-1-ium-2-yl]ethoxy]pyrimidin-2-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5H-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | 著者 | Boettcher, J, Herdeis, L. | 登録日 | 2022-09-06 | 公開日 | 2023-06-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth. Nature, 619, 2023
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3K1Y
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![BU of 3k1y by Molmil](/molmil-images/mine/3k1y) | X-ray structure of oxidoreductase from corynebacterium diphtheriae. orthorombic crystal form, northeast structural genomics consortium target cdr100d | 分子名称: | SULFATE ION, oxidoreductase | 著者 | Kuzin, A, Lew, S, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-29 | 公開日 | 2009-10-20 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target CdR100D To be Published
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5QH6
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![BU of 5qh6 by Molmil](/molmil-images/mine/5qh6) | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with NUOOA000259a | 分子名称: | 2-(3-hydroxyphenyl)-N-(pyridin-2-yl)acetamide, ACETATE ION, DIMETHYL SULFOXIDE, ... | 著者 | Krojer, T, Talon, R, Fairhead, M, Diaz Saez, L, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Ruda, G.F, Szommer, T, Srikannathasan, V, Elkins, J, Spencer, J, London, N, Nelson, A, Brennan, P.E, Huber, K, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | 登録日 | 2018-05-15 | 公開日 | 2019-03-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
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3J4U
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![BU of 3j4u by Molmil](/molmil-images/mine/3j4u) | A new topology of the HK97-like fold revealed in Bordetella bacteriophage: non-covalent chainmail secured by jellyrolls | 分子名称: | cementing protein, major capsid protein | 著者 | Zhang, X, Guo, H, Jin, L, Czornyj, E, Hodes, A, Hui, W.H, Nieh, A.W, Miller, J.F, Zhou, Z.H. | 登録日 | 2013-10-09 | 公開日 | 2013-12-25 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution. Elife, 2, 2013
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6TCG
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3K3N
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![BU of 3k3n by Molmil](/molmil-images/mine/3k3n) | Crystal structure of the catalytic core domain of human PHF8 | 分子名称: | FE (II) ION, PHD finger protein 8 | 著者 | Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z. | 登録日 | 2009-10-03 | 公開日 | 2010-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights into a novel histone demethylase PHF8 Cell Res., 20, 2010
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8B0O
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![BU of 8b0o by Molmil](/molmil-images/mine/8b0o) | Cryo-EM structure apolipoprotein N-acyltransferase Lnt from E.coli in complex with FP3 | 分子名称: | Apolipoprotein N-acyltransferase, [(2~{R})-3-[(2~{R})-3-[[(2~{R})-1-[[(2~{R})-1-[[(2~{R})-6-[(2-aminophenyl)carbonylamino]-1-azanyl-1-oxidanylidene-hexan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-2-(hexadecanoylamino)-3-oxidanylidene-propyl]sulfanyl-2-hexadecanoyloxy-propyl] hexadecanoate | 著者 | Degtjarik, O, Smithers, L, Boland, C, Caffrey, M, Shalev Benami, M. | 登録日 | 2022-09-07 | 公開日 | 2023-07-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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6TKS
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![BU of 6tks by Molmil](/molmil-images/mine/6tks) | Tankyrase 2 in complex with an inhibitor (OM-1720) | 分子名称: | Tankyrase-2, ZINC ION, ~{N}-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]-1,6-naphthyridine-2-carboxamide | 著者 | Sowa, S.T, Lehtio, L. | 登録日 | 2019-11-28 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor. J.Med.Chem., 63, 2020
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3JA4
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6T5S
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![BU of 6t5s by Molmil](/molmil-images/mine/6t5s) | Apo form of C-type lysozyme from the upper gastrointestinal tract of Opisthocomus hoatzin | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme C | 著者 | Taylor, E.J, Skjot, M, Skov, L.K, Klausen, M, De Maria, L, Gippert, G.P, Turkenburg, J.P, Davies, G.J, Wilson, K.S. | 登録日 | 2019-10-17 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The C-Type Lysozyme from the upper Gastrointestinal Tract of Opisthocomus hoatzin, the Stinkbird. Int J Mol Sci, 20, 2019
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8B0L
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![BU of 8b0l by Molmil](/molmil-images/mine/8b0l) | Cryo-EM structure of apolipoprotein N-acyltransferase Lnt from E. coli in complex with PE | 分子名称: | Apolipoprotein N-acyltransferase, PHOSPHATIDYLETHANOLAMINE | 著者 | Degtjarik, O, Smithers, L, Boland, C, Caffrey, M, Shalev Benami, M. | 登録日 | 2022-09-07 | 公開日 | 2023-07-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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8AQ3
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![BU of 8aq3 by Molmil](/molmil-images/mine/8aq3) | In surfo structure of the membrane integral lipoprotein N-acyltransferase Lnt from E. coli in complex with PE | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Huang, C.-Y, Weichert, D, Boland, C, Smithers, L, Olieric, V, Wang, M, Caffrey, M. | 登録日 | 2022-08-11 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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8B0M
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![BU of 8b0m by Molmil](/molmil-images/mine/8b0m) | Cryo-EM structure of apolipoprotein N-acyltransferase Lnt from E. coli in complex with PE (C387S mutant) | 分子名称: | Apolipoprotein N-acyltransferase, PHOSPHATIDYLETHANOLAMINE | 著者 | Degtjarik, O, Smithers, L, Boland, C, Caffrey, M, Shalev Benami, M. | 登録日 | 2022-09-07 | 公開日 | 2023-07-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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8AQ4
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![BU of 8aq4 by Molmil](/molmil-images/mine/8aq4) | In surfo structure of the membrane integral lipoprotein N-acyltransferase Lnt from E. coli in complex with TITC and lyso-PE | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Huang, C.-Y, Weichert, D, Boland, C, Smithers, L, Olieric, V, Wang, M, Caffrey, M. | 登録日 | 2022-08-11 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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3J6Q
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![BU of 3j6q by Molmil](/molmil-images/mine/3j6q) | Identification of the active sites in the methyltransferases of a transcribing dsRNA virus | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, Structural protein VP3 | 著者 | Zhu, B, Yang, C, Liu, H, Cheng, L, Song, F, Zeng, S, Huang, X, Ji, G, Zhu, P. | 登録日 | 2014-03-20 | 公開日 | 2014-10-08 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Identification of the active sites in the methyltransferases of a transcribing dsRNA virus. J.Mol.Biol., 426, 2014
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8B0N
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![BU of 8b0n by Molmil](/molmil-images/mine/8b0n) | Cryo-EM structure of apolipoprotein N-acyltransferase Lnt from E. coli in complex with Lyso-PE | 分子名称: | Apolipoprotein N-acyltransferase, [(2~{S})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-oxidanyl-propan-2-yl] (~{Z})-octadec-9-enoate | 著者 | Degtjarik, O, Smithers, L, Boland, C, Caffrey, M, Shalev Benami, M. | 登録日 | 2022-09-07 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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8B0P
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![BU of 8b0p by Molmil](/molmil-images/mine/8b0p) | Cryo-EM structure of apolipoprotein N-acyltransferase Lnt from E. coli in complex with Pam3 | 分子名称: | Apolipoprotein N-acyltransferase, Pam3-SKKKK, [(2~{S})-3-[(2~{S})-3-azanyl-2-(hexadecanoylamino)-3-oxidanylidene-propyl]sulfanyl-2-hexadecanoyloxy-propyl] hexadecanoate | 著者 | Degtjarik, O, Smithers, L, Boland, C, Caffrey, M, Shalev Benami, M. | 登録日 | 2022-09-07 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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3JC7
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![BU of 3jc7 by Molmil](/molmil-images/mine/3jc7) | Structure of the eukaryotic replicative CMG helicase and pumpjack motion | 分子名称: | Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ... | 著者 | Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E. | 登録日 | 2015-11-24 | 公開日 | 2016-02-10 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation. Nat.Struct.Mol.Biol., 23, 2016
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3JSR
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![BU of 3jsr by Molmil](/molmil-images/mine/3jsr) | X-Ray structure of All0216 protein from Nostoc sp. PCC 7120 at the resolution 1.8A. Northeast Structural Genomics Consortium target NsR236 | 分子名称: | All0216 protein, POTASSIUM ION | 著者 | Kuzin, A.P, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-10 | 公開日 | 2009-09-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-Ray structure of All0216 protein from Nostoc sp. PCC 7120 at the resolution 1.8A To be Published
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6SJC
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![BU of 6sjc by Molmil](/molmil-images/mine/6sjc) | Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)adenosine | 分子名称: | 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, Aspartate--tRNA(Asp) ligase | 著者 | De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2019-08-13 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15, 2020
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6BJ7
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![BU of 6bj7 by Molmil](/molmil-images/mine/6bj7) | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 4-chloro-6-methylpyrimidin-2-amine | 分子名称: | 4-chloro-6-methylpyrimidin-2-amine, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase | 著者 | Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. | 登録日 | 2017-11-05 | 公開日 | 2018-11-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 4-chloro-6-methylpyrimidin-2-amine To Be Published
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5QGK
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![BU of 5qgk by Molmil](/molmil-images/mine/5qgk) | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with FMOPL000679a | 分子名称: | ACETATE ION, DIMETHYL SULFOXIDE, N-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, ... | 著者 | Krojer, T, Talon, R, Fairhead, M, Diaz Saez, L, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Ruda, G.F, Szommer, T, Srikannathasan, V, Elkins, J, Spencer, J, London, N, Nelson, A, Brennan, P.E, Huber, K, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | 登録日 | 2018-05-15 | 公開日 | 2019-03-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
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