2IZZ
 
 | Crystal structure of human pyrroline-5-carboxylate reductase | 分子名称: | 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRROLINE-5-CARBOXYLATE REDUCTASE 1 | 著者 | Pike, A.C.W, Guo, K, Kavanagh, K, Pilka, E.S, Berridge, G, Colebrook, S, Bray, J, Salah, E, Savitsky, P, Papagrigoriou, E, Turnbull, A.P, von Delft, F, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Oppermann, U. | 登録日 | 2006-07-31 | 公開日 | 2006-08-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of Human Pyrroline-5-Carboxylate Reductase To be Published
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2IXS
 
 | Structure of SdaI restriction endonuclease | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SDAI RESTRICTION ENDONUCLEASE, ... | 著者 | Tamulaitiene, G, Jakubauskas, A, Urbanke, C, Huber, R, Grazulis, S, Siksnys, V. | 登録日 | 2006-07-11 | 公開日 | 2006-09-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of the Rare-Cutting Restriction Enzyme Sdai Reveals Unexpected Domain Architecture Structure, 14, 2006
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2J6B
 
 | crystal structure of AFV3-109, a highly conserved protein from crenarchaeal viruses | 分子名称: | AFV3-109 | 著者 | Keller, J, Leulliot, N, Cambillau, C, Campanacci, V, Porciero, S, Prangishvili, D, Cortez, D, Quevillon-Cheruel, S, Van Tilbeurgh, H. | 登録日 | 2006-09-27 | 公開日 | 2007-02-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal Structure of Afv3-109, a Highly Conserved Protein from Crenarchaeal Viruses. Virol J., 4, 2007
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8I7S
 
 | The crystal structure of human abl1 kinase domain in complex with ABL1-B1 | 分子名称: | 5-[3-(2-methoxy-5-oxidanyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-pyridine-3-carboxamide, Tyrosine-protein kinase ABL1 | 著者 | Zhu, C, Zhang, Z. | 登録日 | 2023-02-02 | 公開日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.94635463 Å) | 主引用文献 | Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies. J Adv Res, 2024
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8I7Z
 
 | The crystal structure of human abl1 kinase domain in complex with ABL1-B5 | 分子名称: | 5-[3-(2-methoxy-5-oxidanyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-pyridine-3-carboxamide, BETA-ALANINE, Tyrosine-protein kinase ABL1 | 著者 | Zhu, C, Zhang, Z. | 登録日 | 2023-02-02 | 公開日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.25495815 Å) | 主引用文献 | Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies. J Adv Res, 2024
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8I7T
 
 | The crystal structure of human abl1 kinase domain in complex with ABL1-B4 | 分子名称: | Tyrosine-protein kinase ABL1, [3-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-methoxy-phenyl] ethanesulfonate | 著者 | Zhu, C, Zhang, Z. | 登録日 | 2023-02-02 | 公開日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.80004954 Å) | 主引用文献 | Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies. J Adv Res, 2024
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2J9P
 
 | Crystal structure of the Bacillus subtilis PBP4a, and its complex with a peptidoglycan mimetic peptide. | 分子名称: | (2R)-2-AMINO-7-{[(1R)-1-CARBOXYETHYL]AMINO}-7-OXOHEPTANOIC ACID, D-ALANINE, D-alanyl-D-alanine carboxypeptidase DacC | 著者 | Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | 登録日 | 2006-11-15 | 公開日 | 2007-07-03 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide. J. Mol. Biol., 371, 2007
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2IKK
 
 | Structural Genomics, the crystal structure of the C-terminal domain of Yurk from Bacillus subtilis subsp. subtilis str. 168 | 分子名称: | Hypothetical transcriptional regulator yurK, SULFATE ION | 著者 | Tan, K, Hatzos, C, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-10-02 | 公開日 | 2006-10-31 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of the C-terminal domain of Yurk from Bacillus subtilis subsp. subtilis str. 168 To be Published
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2IDK
 
 | Crystal Structure of Rat Glycine N-Methyltransferase Complexed With Folate | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C. | 登録日 | 2006-09-15 | 公開日 | 2006-12-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | 5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase. J.Biol.Chem., 282, 2007
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8IQY
 
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8IQV
 
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2IQI
 
 | Crystal structure of protein XCC0632 from Xanthomonas campestris, Pfam DUF330 | 分子名称: | Hypothetical protein XCC0632 | 著者 | Bonanno, J.B, Gilmore, J, Bain, K.T, Mckenzie, C, Pelletier, L, Wasserman, S, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2006-10-13 | 公開日 | 2006-11-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of hypothetical protein XCC0632 from Xanthomonas campestris pv. campestris To be Published
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8IQW
 
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8IQZ
 
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8IY7
 
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8IZZ
 
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2IVF
 
 | Ethylbenzene dehydrogenase from Aromatoleum aromaticum | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, ACETATE ION, ... | 著者 | Kloer, D.P, Hagel, C, Heider, J, Schulz, G.E. | 登録日 | 2006-06-13 | 公開日 | 2006-09-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structure of Ethylbenzene Dehydrogenase from Aromatoleum Aromaticum Structure, 14, 2006
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2J0G
 
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2J86
 
 | Structural analysis of the PP2C Family Phosphatase tPphA of Thermosynechococcus elongatus | 分子名称: | MAGNESIUM ION, PROTEIN SERINE-THREONINE PHOSPHATASE | 著者 | Schlicker, C, Kloft, N, Forchhammer, K, Becker, S. | 登録日 | 2006-10-19 | 公開日 | 2007-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural Analysis of the Pp2C Phosphatase Tppha from Thermosynechococcus Elongatus: A Flexible Flap Subdomain Controls Access to the Catalytic Site. J.Mol.Biol., 376, 2008
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8GCC
 
 | T. cruzi topoisomerase II alpha bound to dsDNA and the covalent inhibitor CT1 | 分子名称: | 2-{3-[(Z)-iminomethyl]-1H-1,2,4-triazol-1-yl}-1-{(3M)-3-[2-(trifluoromethyl)phenyl]-6H-pyrrolo[3,4-b]pyridin-6-yl}ethan-1-one, DNA (28-MER), DNA topoisomerase 2 | 著者 | Schenk, A, Deniston, C, Noeske, J. | 登録日 | 2023-03-01 | 公開日 | 2023-07-12 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380, 2023
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2ID2
 
 | GAPN T244S mutant X-ray structure at 2.5 A | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION | 著者 | Pailot, A, D'Ambrosio, K, Corbier, C, Talfournier, F, Branlant, G. | 登録日 | 2006-09-14 | 公開日 | 2007-09-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Invariant Thr(244) is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans. Biochem.J., 400, 2006
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2IZS
 
 | Structure of casein kinase gamma 3 in complex with inhibitor | 分子名称: | CASEIN KINASE I ISOFORM GAMMA-3, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Bunkoczi, G, Salah, E, Rellos, P, Das, S, Fedorov, O, Savitsky, P, Debreczeni, J.E, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. | 登録日 | 2006-07-26 | 公開日 | 2006-08-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Inhibitor Binding by Casein Kinases To be Published
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7B83
 
 | Structure of SARS-CoV-2 Main Protease bound to pyrithione zinc | 分子名称: | 3C-like proteinase, 9-oxa-7-thia-1-azonia-8$l^{2}-zincabicyclo[4.3.0]nona-1,3,5-triene, CHLORIDE ION, ... | 著者 | Guenther, S, Reinke, P, Oberthuer, D, Yefanov, O, Gelisio, L, Ginn, H, Lieske, J, Domaracky, M, Brehm, W, Rahmani Mashour, A, White, T.A, Knoska, J, Pena Esperanza, G, Koua, F, Tolstikova, A, Groessler, M, Fischer, P, Hennicke, V, Fleckenstein, H, Trost, F, Galchenkova, M, Gevorkov, Y, Li, C, Awel, S, Paulraj, L.X, Ullah, N, Falke, S, Alves Franca, B, Schwinzer, M, Brognaro, H, Werner, N, Perbandt, M, Tidow, H, Seychell, B, Beck, T, Meier, S, Doyle, J.J, Giseler, H, Melo, D, Dunkel, I, Lane, T.J, Peck, A, Saouane, S, Hakanpaeae, J, Meyer, J, Noei, H, Gribbon, P, Ellinger, B, Kuzikov, M, Wolf, M, Zhang, L, Ehrt, C, Pletzer-Zelgert, J, Wollenhaupt, J, Feiler, C, Weiss, M, Schulz, E.C, Mehrabi, P, Norton-Baker, B, Schmidt, C, Lorenzen, K, Schubert, R, Han, H, Chari, A, Fernandez Garcia, Y, Turk, D, Hilgenfeld, R, Rarey, M, Zaliani, A, Chapman, H.N, Pearson, A, Betzel, C, Meents, A. | 登録日 | 2020-12-12 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
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6Q0Q
 
 | Crystal structure of Human galectin-3 CRD in complex with Methyl 3-O-(1-{3-O-[1-(b-D-galactopyranosyl)-1,2,3-triazol-4-yl]-methyl-b-D-galactopyranosyl}-1,2,3-triazol-4-yl)-methyl-b-D-galactopyranoside | 分子名称: | (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[4-[[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[4-[[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-methoxy-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]-1,2,3-triazol-1-yl]-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]-1,2,3-triazol-1-yl]oxane-3,4,5-triol, CHLORIDE ION, Galectin-3 | 著者 | Kishor, C, Blanchard, H. | 登録日 | 2019-08-02 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.98601174 Å) | 主引用文献 | Linear triazole-linked pseudo oligogalactosides as scaffolds for galectin inhibitor development. Chem.Biol.Drug Des., 96, 2020
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6Q17
 
 | Crystal structure of Human galectin-3 CRD in complex with Methyl 3-O-[1-(b-D-galactopyranosyl)-1,2,3-triazol-4-yl]-methyl-b-D-galactopyranoside | 分子名称: | CHLORIDE ION, Galectin-3, methyl 3-O-[(1-beta-D-galactopyranosyl-1H-1,2,3-triazol-4-yl)methyl]-beta-D-galactopyranoside | 著者 | Kishor, C, Blanchard, H. | 登録日 | 2019-08-02 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Linear triazole-linked pseudo oligogalactosides as scaffolds for galectin inhibitor development. Chem.Biol.Drug Des., 96, 2020
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