2V9L
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2V6O
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![BU of 2v6o by Molmil](/molmil-images/mine/2v6o) | Structure of Schistosoma mansoni Thioredoxin-Glutathione Reductase (SmTGR) | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NITRATE ION, TETRAETHYLENE GLYCOL, ... | 著者 | Miele, A.E, Angelucci, F, Boumis, G, Dimastrogiovanni, D, Bellelli, A, Brunori, M. | 登録日 | 2007-07-19 | 公開日 | 2008-03-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Glutathione Reductase and Thioredoxin Reductase at the Crossroad: The Structure of Schistosoma Mansoni Thioredoxin Glutathione Reductase Proteins, 72, 2008
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7OIF
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![BU of 7oif by Molmil](/molmil-images/mine/7oif) | CspA-27 cotranslational folding intermediate 2 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. | 登録日 | 2021-05-11 | 公開日 | 2022-01-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A switch from alpha-helical to beta-strand conformation during co-translational protein folding. Embo J., 41, 2022
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2V9M
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5LT8
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1PQI
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![BU of 1pqi by Molmil](/molmil-images/mine/1pqi) | T4 LYSOZYME CORE REPACKING MUTANT I118L/CORE7/TA | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ... | 著者 | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | 登録日 | 2003-06-18 | 公開日 | 2003-10-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Repacking the Core of T4 Lysozyme by Automated Design J.Mol.Biol., 332, 2003
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7OIG
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![BU of 7oig by Molmil](/molmil-images/mine/7oig) | CspA-27 cotranslational folding intermediate 3 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. | 登録日 | 2021-05-11 | 公開日 | 2022-01-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A switch from alpha-helical to beta-strand conformation during co-translational protein folding. Embo J., 41, 2022
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5LVN
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![BU of 5lvn by Molmil](/molmil-images/mine/5lvn) | Human PDK1 Kinase Domain in Complex with Adenosine Bound to the ATP-Binding Site | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENOSINE, CHLORIDE ION, ... | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | 登録日 | 2016-09-14 | 公開日 | 2016-10-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.379 Å) | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase. Cell Chem Biol, 23, 2016
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2V9J
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![BU of 2v9j by Molmil](/molmil-images/mine/2v9j) | Crystal structure of the regulatory fragment of mammalian AMPK in complexes with Mg.ATP-AMP | 分子名称: | 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ... | 著者 | Xiao, B, Heath, R, Saiu, P, Leiper, F.C, Leone, P, Jing, C, Walker, P.A, Haire, L, Eccleston, J.F, Davis, C.T, Martin, S.R, Carling, D, Gamblin, S.J. | 登録日 | 2007-08-23 | 公開日 | 2007-09-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase Nature, 449, 2007
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7NWW
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![BU of 7nww by Molmil](/molmil-images/mine/7nww) | CspA-27 cotranslational folding intermediate 1 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. | 登録日 | 2021-03-17 | 公開日 | 2022-01-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | A switch from alpha-helical to beta-strand conformation during co-translational protein folding. Embo J., 41, 2022
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1PU1
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![BU of 1pu1 by Molmil](/molmil-images/mine/1pu1) | Solution structure of the Hypothetical protein mth677 from Methanothermobacter Thermautotrophicus | 分子名称: | Hypothetical protein MTH677 | 著者 | Blanco, F.J, Yee, A, Campos-Olivas, R, Devos, D, Valencia, A, Arrowsmith, C.H, Rico, M. | 登録日 | 2003-06-23 | 公開日 | 2004-06-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the hypothetical protein Mth677 from Methanobacterium thermoautotrophicum: A novel {alpha}+{beta} fold Protein Sci., 13, 2004
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7OII
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![BU of 7oii by Molmil](/molmil-images/mine/7oii) | CspA-70 cotranslational folding intermediate 2 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. | 登録日 | 2021-05-11 | 公開日 | 2022-01-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A switch from alpha-helical to beta-strand conformation during co-translational protein folding. Embo J., 41, 2022
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2UY7
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![BU of 2uy7 by Molmil](/molmil-images/mine/2uy7) | Crystal structure of the P pilus rod subunit PapA | 分子名称: | PAP FIMBRIAL MAJOR PILIN PROTEIN, PERIPLASMID CHAPERONE PAPD PROTEIN, SULFATE ION | 著者 | Verger, D, Bullitt, E, Hultgren, S.J, Waksman, G. | 登録日 | 2007-04-02 | 公開日 | 2007-05-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of the P Pilus Rod Subunit Papa. Plos Pathog., 3, 2007
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5LVP
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![BU of 5lvp by Molmil](/molmil-images/mine/5lvp) | Human PDK1 Kinase Domain in Complex with an HM-Peptide Bound to the PIF-Pocket | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | 登録日 | 2016-09-14 | 公開日 | 2016-10-19 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase. Cell Chem Biol, 23, 2016
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1NYW
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![BU of 1nyw by Molmil](/molmil-images/mine/1nyw) | The high resolution structures of RmlC from Streptoccus suis in complex with dTDP-D-glucose | 分子名称: | 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase | 著者 | Dong, C, Major, L.L, Allen, A, Blankenfeldt, W, Maskell, D, Naismith, J.H. | 登録日 | 2003-02-14 | 公開日 | 2003-06-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-Resolution Structures of RmlC from Streptococcus suis in Complex with Substrate Analogs Locate the Active Site of This Class of Enzyme Structure, 11, 2003
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1NZC
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![BU of 1nzc by Molmil](/molmil-images/mine/1nzc) | The high resolution structures of RmlC from Streptococcus suis in complex with dTDP-D-xylose | 分子名称: | NICKEL (II) ION, THYMIDINE-5'-DIPHOSPHO-BETA-D-XYLOSE, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase | 著者 | Dong, C, Major, L.L, Allen, A, Blankenfeldt, W, Maskell, D, Naismith, J.H. | 登録日 | 2003-02-17 | 公開日 | 2003-06-24 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High-Resolution Structures of RmlC from Streptococcus suis in Complex with Substrate Analogs Locate the Active Site of This Class of Enzyme Structure, 11, 2003
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7NTO
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![BU of 7nto by Molmil](/molmil-images/mine/7nto) | The structure of RRM domain of human TRMT2A at 1.23 A resolution | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... | 著者 | Witzenberger, M, Janowski, R, Davydova, E, Niessing, D. | 登録日 | 2021-03-10 | 公開日 | 2022-01-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death. Comput Struct Biotechnol J, 20, 2022
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1NZQ
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![BU of 1nzq by Molmil](/molmil-images/mine/1nzq) | D-Phe-Pro-Arg-Type Thrombin Inhibitor | 分子名称: | (2-{2-[(5-CARBAMIMIDOYL-1-METHYL-1H-PYRROL-3-YLMETHYL)-CARBAMOYL]-PYRROL-1-YL} -1-CYCLOHEXYLMETHYL-2-OXO-ETHYLAMINO)-ACETIC ACID, Decapeptide Hirudin Analogue, Thrombin heavy chain, ... | 著者 | Lange, U.E, Bauke, D, Hornberger, W, Mack, H, Seitz, W, Hoeffken, H.W. | 登録日 | 2003-02-19 | 公開日 | 2003-10-14 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety Bioorg.Med.Chem.Lett., 13, 2003
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2UUP
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![BU of 2uup by Molmil](/molmil-images/mine/2uup) | Crystal structure of MurD ligase in complex with D-Glu containing sulfonamide inhibitor | 分子名称: | N-({6-[(4-CYANOBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID, SULFATE ION, UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE | 著者 | Humljan, J, Kotnik, M, Contreras-Martel, C, Blanot, D, Urleb, U, Dessen, A, Solmajer, T, Gobec, S. | 登録日 | 2007-03-06 | 公開日 | 2008-03-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme. J. Med. Chem., 51, 2008
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7NXH
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![BU of 7nxh by Molmil](/molmil-images/mine/7nxh) | Structure of SARS-CoV2 NSP5 (3C-like proteinase) determined in-house | 分子名称: | 3C-like proteinase | 著者 | Calderone, V, Grifagni, D, Cantini, F, Fragai, M, Banci, L. | 登録日 | 2021-03-18 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | SARS-CoV-2 M pro inhibition by a zinc ion: structural features and hints for drug design. Chem.Commun.(Camb.), 57, 2021
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2UW1
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![BU of 2uw1 by Molmil](/molmil-images/mine/2uw1) | Ivy Desaturase Structure | 分子名称: | (3R)-3-HYDROXY-5,5-DIMETHYLHEXANOIC ACID, FE (III) ION, PLASTID DELTA4 MULTIFUNCTIONAL ACYL-ACYL CARRIER PROTEIN DESATURASE, ... | 著者 | Guy, J.E, Whittle, E, Kumaran, D, Lindqvist, Y, Shanklin, J. | 登録日 | 2007-03-15 | 公開日 | 2007-05-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Crystal Structure of the Ivy {Delta}4-16:0-Acp Desaturase Reveals Structural Details of the Oxidized Active Site and Potential Determinants of Regioselectivity. J.Biol.Chem., 282, 2007
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1O28
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![BU of 1o28 by Molmil](/molmil-images/mine/1o28) | Crystal structure of Thymidylate Synthase Complementing Protein (TM0449) from Thermotoga maritima with FdUMP at 2.1 A resolution | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, TRIETHYLENE GLYCOL, ... | 著者 | Mathews, I.I, Deacon, A.M, Canaves, J.M, McMullan, D, Lesley, S.A, Agarwalla, S, Kuhn, P, Joint Center for Structural Genomics (JCSG) | 登録日 | 2003-02-18 | 公開日 | 2003-06-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional Analysis of Substrate and Cofactor Complex Structures of a Thymidylate Synthase-Complementing Protein Structure, 11, 2003
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5LYX
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![BU of 5lyx by Molmil](/molmil-images/mine/5lyx) | CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX; WITH AN INHIBITOR 5-((R)-1-[1,2,4]Triazolo[1,5-a]pyrimidin-7-yl-pyrrolidin-2-ylmethoxy)-isoquinoline | 分子名称: | 5-[[(2~{R})-1-([1,2,4]triazolo[1,5-a]pyrimidin-7-yl)pyrrolidin-2-yl]methoxy]isoquinoline, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Musil, D, Heinrich, T, Lehmann, M. | 登録日 | 2016-09-29 | 公開日 | 2017-08-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Novel reversible methionine aminopeptidase-2 (MetAP-2) inhibitors based on purine and related bicyclic templates. Bioorg. Med. Chem. Lett., 27, 2017
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1O2G
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![BU of 1o2g by Molmil](/molmil-images/mine/1o2g) | Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors | 分子名称: | 3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIPHENYL-2-OLATE, ACETYL HIRUDIN, SODIUM ION, ... | 著者 | Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, W.F, Hui, H, Breitenbucher, G, Allen, D, Janc, J. | 登録日 | 2003-03-06 | 公開日 | 2003-05-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Elaborate Manifold of Short Hydrogen Bond Arrays Mediating
Binding of Active Site-Directed Serine Protease Inhibitors J.Mol.Biol., 329, 2003
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1O2J
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![BU of 1o2j by Molmil](/molmil-images/mine/1o2j) | Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors | 分子名称: | 2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-6-ISOBUTOXYBENZENOLATE, BETA-TRYPSIN, CALCIUM ION, ... | 著者 | Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, W.F, Hui, H, Breitenbucher, G, Allen, D, Janc, J. | 登録日 | 2003-03-06 | 公開日 | 2003-05-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Elaborate Manifold of Short Hydrogen Bond Arrays Mediating
Binding of Active Site-Directed Serine Protease Inhibitors J.Mol.Biol., 329, 2003
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