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4KT5
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BU of 4kt5 by Molmil
Structure of GrlR-GrlA complex
分子名称: GrlA, GrlR, TETRAETHYLENE GLYCOL
著者Padavannil, A, Jobichen, C, Sivaraman, J.
登録日2013-05-20
公開日2013-10-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of GrlR-GrlA complex that prevents GrlA activation of virulence genes
Nat Commun, 4, 2013
3E3C
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BU of 3e3c by Molmil
Structure of GrlR-lipid complex
分子名称: (2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL HEXANOATE, L0044
著者Jobichen, C, Sivaraman, J.
登録日2008-08-07
公開日2009-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification and characterization of the lipid binding property of GrlR, a locus of enterocyte effacement regulator.
Biochem.J., 2009
3EBK
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BU of 3ebk by Molmil
Crystal structure of major allergens, Bla g 4 from cockroaches
分子名称: Allergen Bla g 4
著者Tan, Y.W, Chan, S.L, Chew, F.T, Sivaraman, J, Mok, Y.K.
登録日2008-08-28
公開日2008-12-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of two major allergens, Bla g 4 and Per a 4, from cockroaches and their IgE binding epitopes.
J.Biol.Chem., 284, 2008
2MQ1
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BU of 2mq1 by Molmil
Phosphotyrosine binding domain
分子名称: E3 ubiquitin-protein ligase Hakai, ZINC ION
著者Mukherjee, M, Jing-Song, F, Sivaraman, J.
登録日2014-06-11
公開日2014-08-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structure.
J.Biol.Chem., 289, 2014
6K3O
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BU of 6k3o by Molmil
Cryo-EM structure of Apo-bacterioferritin from Streptomyces coelicolor
分子名称: Bacterioferritin, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE
著者Jobichen, C, Sivaraman, J.
登録日2019-05-21
公開日2021-02-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of Apo-bacterioferritin from Streptomyces coelicolor.
To Be Published
6K43
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Cryo-EM structure of Holo-bacterioferritin-form-I from Streptomyces coelicolor
分子名称: Bacterioferritin, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE
著者Jobichen, C, Sivaraman, J.
登録日2019-05-23
公開日2021-02-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of Apo-bacterioferritin from Streptomyces coelicolor.
To Be Published
6K4M
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BU of 6k4m by Molmil
Cryo-EM structure of Holo-bacterioferritin form-II from Streptomyces coelicolor
分子名称: Bacterioferritin, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE
著者Jobichen, C, Sivaraman, J.
登録日2019-05-24
公開日2021-02-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of Bacterioferritin from Streptomyces coelicolor
To Be Published
2OVS
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BU of 2ovs by Molmil
Crystal structure of a Type Three secretion System protein
分子名称: L0044, TETRAETHYLENE GLYCOL
著者Jobichen, C, Li, M, Sivaraman, J.
登録日2007-02-15
公開日2007-05-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of GrlR and the implication of its EDED motif in mediating the regulation of type III secretion system in EHEC.
Plos Pathog., 3, 2007
1K75
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BU of 1k75 by Molmil
The L-histidinol dehydrogenase (hisD) structure implicates domain swapping and gene duplication.
分子名称: GLYCEROL, L-histidinol dehydrogenase, SULFATE ION
著者Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2001-10-18
公開日2002-02-27
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
3ELP
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BU of 3elp by Molmil
Structure of cystationine gamma lyase
分子名称: Cystathionine gamma-lyase
著者Sun, Q, Sivaraman, J.
登録日2008-09-23
公開日2008-11-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S
J.Biol.Chem., 284, 2009
3EBW
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BU of 3ebw by Molmil
Crystal structure of major allergens, Per a 4 from cockroaches
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Per a 4 allergen
著者Tan, Y.W, Chan, S.L, Chew, F.T, Sivaraman, J, Mok, Y.K.
登録日2008-08-28
公開日2008-12-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of two major allergens, Bla g 4 and Per a 4, from cockroaches and their IgE binding epitopes.
J.Biol.Chem., 284, 2008
1MHW
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BU of 1mhw by Molmil
Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
分子名称: 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L
著者Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O.
登録日2002-08-21
公開日2002-12-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
J.Med.Chem., 45, 2002
4NQF
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BU of 4nqf by Molmil
Crystal structure of HEPN domain protein
分子名称: Nucleotidyltransferase
著者Padavannil, A, Jobichen, C, Sivaraman, J.
登録日2013-11-25
公開日2014-03-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Dimerization of VirD2 Binding Protein Is Essential for Agrobacterium Induced Tumor Formation in Plants
Plos Pathog., 10, 2014
4PLJ
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BU of 4plj by Molmil
Hepatitis E Virus E2s domain (Genotype IV) in complex with a neutralizing antibody 8G12
分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein
著者Tang, X.H, Li, S.W, Sivaraman, J.
登録日2014-05-18
公開日2015-04-15
最終更新日2015-05-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody
Cell Res., 25, 2015
4PLK
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BU of 4plk by Molmil
Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody 8G12
分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein
著者Tang, X.H, Li, S.W, Sivaraman, J.
登録日2014-05-18
公開日2015-04-08
最終更新日2015-05-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody
Cell Res., 25, 2015
1PVJ
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BU of 1pvj by Molmil
Crystal structure of the Streptococcal pyrogenic exotoxin B (SpeB)- inhibitor complex
分子名称: (3R)-3-{[(BENZYLOXY)CARBONYL]AMINO}-2-OXO-4-PHENYLBUTANE-1-DIAZONIUM, pyrogenic exotoxin B
著者Ziomek, E, Sivaraman, J, Doran, J, Menard, R, Cygler, M.
登録日2003-06-27
公開日2004-09-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Inhibition of autoprocessing of the streptococcal pyrogenic exotoxin B (speB). Crystal structure of the proenzyme-inhibitor complex
To be published
5XWE
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BU of 5xwe by Molmil
Structure of a three finger toxin from Ophiophagus hannah venom
分子名称: CHLORIDE ION, GLYCEROL, Weak toxin DE-1 homolog 1, ...
著者Jobichen, C, Roy, A, Kini, R.M, Sivaraman, J.
登録日2017-06-29
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a three finger toxin from Ophiophagus hannah venom
To Be Published
5YDX
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BU of 5ydx by Molmil
NMR structure of YAP1-2 WW1 domain with LATS1 PPxY motif complex
分子名称: WW domain with PPxY motif
著者Fan, J.S, Sivaraman, J.
登録日2017-09-15
公開日2018-05-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
5YDY
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BU of 5ydy by Molmil
NMR structure of YAP1-2 WW2 domain with LATS1 PPxY motif complex
分子名称: WW2 domain and PPxY motif complex
著者Fan, J.S, Sivaraman, J.
登録日2017-09-15
公開日2018-05-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
7EDD
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BU of 7edd by Molmil
Crystal structure of a serine protease from Streptococcus pyogenes
分子名称: C5a peptidase, CALCIUM ION, CHLORIDE ION, ...
著者Jobichen, C, Sivaraman, J.
登録日2021-03-15
公開日2021-05-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.897 Å)
主引用文献The Autocatalytic Cleavage Domain Is Not Required for the Activity of ScpC, a Virulence Protease from Streptococcus pyogenes : A Structural Insight.
Biochemistry, 60, 2021
1CJL
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BU of 1cjl by Molmil
CRYSTAL STRUCTURE OF A CYSTEINE PROTEASE PROFORM
分子名称: PROCATHEPSIN L
著者Coulombe, R, Grochulski, P, Sivaraman, J, Cygler, M.
登録日1996-07-24
公開日1997-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
1KAR
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BU of 1kar by Molmil
L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH HISTAMINE (INHIBITOR), ZINC AND NAD (COFACTOR)
分子名称: HISTAMINE, Histidinol dehydrogenase, ZINC ION
著者Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M.
登録日2001-11-02
公開日2002-06-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
7E0W
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Crystal Structure of BCH domain from S. pombe
分子名称: Putative Rho GTPase-activating protein C1565.02c, TETRAETHYLENE GLYCOL
著者Chichili, V.P.R, Jobichen, C, Sivaraman, J.
登録日2021-01-28
公開日2021-03-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel intertwined anti-parallel dimeric structure of scaffold BCH domain regulates RhoA and RhoGAP functions
Proc.Natl.Acad.Sci.USA, 2021
1KAE
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BU of 1kae by Molmil
L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINOL (SUBSTRATE), ZINC AND NAD (COFACTOR)
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Histidinol dehydrogenase, ...
著者Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M.
登録日2001-11-01
公開日2002-06-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1LKZ
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Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli.
分子名称: Ribose 5-phosphate isomerase A
著者Rangarajan, E.S, Sivaraman, J, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2002-04-26
公開日2002-05-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli
Proteins, 48, 2002

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