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1NPZ
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BU of 1npz by Molmil
Crystal structures of Cathepsin S inhibitor complexes
分子名称: Cathepsin S, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide
著者Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Seddon, A.P, Menard, R, Cygler, M, Rath, V.L.
登録日2003-01-20
公開日2003-04-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry, 42, 2003
3BUN
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BU of 3bun by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty4
分子名称: 13-meric peptide from Protein sprouty homolog 4, E3 ubiquitin-protein ligase CBL
著者Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUX
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BU of 3bux by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in c-Met
分子名称: 13-meric peptide from Hepatocyte growth factor receptor, E3 ubiquitin-protein ligase CBL
著者Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUM
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BU of 3bum by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2
分子名称: E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2
著者Ng, C, Jackson, A.R, Buschdorf, P.J, Sun, Q, Guy, R.G, Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUW
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BU of 3buw by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Syk
分子名称: 13-meric peptide from Tyrosine-protein kinase SYK, E3 ubiquitin-protein ligase CBL
著者Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3BUO
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BU of 3buo by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in EGF receptor'
分子名称: 13-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL
著者Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J.
登録日2008-01-03
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
3EAA
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BU of 3eaa by Molmil
Structure of a type six secretion system protein
分子名称: EvpC
著者Jobichen, C, Sivaraman, J.
登録日2008-08-25
公開日2009-08-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Structural basis for the secretion of EvpC: a key type VI secretion system protein from Edwardsiella tarda
Plos One, 5, 2010
7CBK
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BU of 7cbk by Molmil
Structure of Human Neutrophil Elastase Ecotin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ecotin, ...
著者Jobichen, C, Sivaraman, J.
登録日2020-06-12
公開日2020-08-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site.
Biochemistry, 59, 2020
2OVS
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BU of 2ovs by Molmil
Crystal structure of a Type Three secretion System protein
分子名称: L0044, TETRAETHYLENE GLYCOL
著者Jobichen, C, Li, M, Sivaraman, J.
登録日2007-02-15
公開日2007-05-29
最終更新日2020-09-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of GrlR and the implication of its EDED motif in mediating the regulation of type III secretion system in EHEC.
Plos Pathog., 3, 2007
7E0W
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BU of 7e0w by Molmil
Crystal Structure of BCH domain from S. pombe
分子名称: Putative Rho GTPase-activating protein C1565.02c, TETRAETHYLENE GLYCOL
著者Chichili, V.P.R, Jobichen, C, Sivaraman, J.
登録日2021-01-28
公開日2021-03-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel intertwined anti-parallel dimeric structure of scaffold BCH domain regulates RhoA and RhoGAP functions
Proc.Natl.Acad.Sci.USA, 2021
1K75
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BU of 1k75 by Molmil
The L-histidinol dehydrogenase (hisD) structure implicates domain swapping and gene duplication.
分子名称: GLYCEROL, L-histidinol dehydrogenase, SULFATE ION
著者Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2001-10-18
公開日2002-02-27
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
7EDD
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BU of 7edd by Molmil
Crystal structure of a serine protease from Streptococcus pyogenes
分子名称: C5a peptidase, CALCIUM ION, CHLORIDE ION, ...
著者Jobichen, C, Sivaraman, J.
登録日2021-03-15
公開日2021-05-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.897 Å)
主引用文献The Autocatalytic Cleavage Domain Is Not Required for the Activity of ScpC, a Virulence Protease from Streptococcus pyogenes : A Structural Insight.
Biochemistry, 60, 2021
2Q1K
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BU of 2q1k by Molmil
Cyrstal Structure of AscE from Aeromonas hydrophilla
分子名称: AscE
著者Tan, Y.W, Yu, H.B, Leung, K.Y, Sivaraman, J, Mok, Y.K.
登録日2007-05-24
公開日2008-06-03
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of AscE and induced burial regions in AscE and AscG upon formation of the chaperone needle-subunit complex of type III secretion system in Aeromonas hydrophila.
Protein Sci., 17, 2008
7FCF
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BU of 7fcf by Molmil
Crystal structure of T6SS Hcp protein
分子名称: Fimbrial protein
著者Jobichen, C, Sivaraman, J.
登録日2021-07-14
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Bacterial antagonism of Chromobacterium haemolyticum and characterization of its putative type VI secretion system.
Res.Microbiol., 173, 2022
2QHD
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BU of 2qhd by Molmil
Crystal structure of ecarpholin S (ser49-PLA2) complexed with fatty acid
分子名称: LAURIC ACID, Phospholipase A2
著者Zhou, X, Tan, T.C, Valiyaveettil, S, Go, M.L, Kini, R.M, Sivaraman, J.
登録日2007-07-02
公開日2007-10-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Characterization of Myotoxic Ecarpholin S from Echis carinatus Venom
Biophys.J., 95, 2008
7EQZ
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BU of 7eqz by Molmil
Crystal structure of Carboxypeptidase B complexed with Potato Carboxypeptidase Inhibitor
分子名称: Carboxypeptidase B, GLYCINE, Metallocarboxypeptidase inhibitor, ...
著者Choong, Y.K, Gavor, E, Jobichen, C, Sivaraman, J.
登録日2021-05-05
公開日2021-11-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Aedes aegypti carboxypeptidase B1-inhibitor complex uncover the disparity between mosquito and non-mosquito insect carboxypeptidase inhibition mechanism.
Protein Sci., 30, 2021
2QHE
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BU of 2qhe by Molmil
Crystal structure of Ser49-PLA2 (ecarpholin S) from Echis carinatus sochureki snake venom
分子名称: Phospholipase A2
著者Zhou, X, Valiyaveettil, S, Go, M.L, Kini, R.M, Sivaraman, J.
登録日2007-07-02
公開日2007-10-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of Myotoxic Ecarpholin S from Echis carinatus Venom
Biophys.J., 95, 2008
4NQF
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BU of 4nqf by Molmil
Crystal structure of HEPN domain protein
分子名称: Nucleotidyltransferase
著者Padavannil, A, Jobichen, C, Sivaraman, J.
登録日2013-11-25
公開日2014-03-26
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Dimerization of VirD2 Binding Protein Is Essential for Agrobacterium Induced Tumor Formation in Plants
Plos Pathog., 10, 2014
4PLJ
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BU of 4plj by Molmil
Hepatitis E Virus E2s domain (Genotype IV) in complex with a neutralizing antibody 8G12
分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein
著者Tang, X.H, Li, S.W, Sivaraman, J.
登録日2014-05-18
公開日2015-04-15
最終更新日2015-05-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody
Cell Res., 25, 2015
4PLK
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BU of 4plk by Molmil
Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody 8G12
分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein
著者Tang, X.H, Li, S.W, Sivaraman, J.
登録日2014-05-18
公開日2015-04-08
最終更新日2015-05-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody
Cell Res., 25, 2015
3RKD
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BU of 3rkd by Molmil
Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody
分子名称: Capsid protein, Monoclonal Antibody, Heavy Chain, ...
著者Tang, X.H, Sivaraman, J.
登録日2011-04-18
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the neutralization and genotype specificity of hepatitis E virus
Proc.Natl.Acad.Sci.USA, 108, 2011
3RJ2
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BU of 3rj2 by Molmil
Structural and functional characterization of a novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus (SGIV)
分子名称: Putative uncharacterized protein
著者Chen, L, Liu, Y, Sivaraman, J, Hew, C.L.
登録日2011-04-15
公開日2012-02-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus
J.Virol., 85, 2011
3RKC
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BU of 3rkc by Molmil
Hepatitis E Virus Capsid Protein E2s Domain (genotype IV)
分子名称: Capsid protein
著者Tang, X.H, Sivaraman, J.
登録日2011-04-18
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural basis for the neutralization and genotype specificity of hepatitis E virus
Proc.Natl.Acad.Sci.USA, 108, 2011
3WX6
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BU of 3wx6 by Molmil
Crystal structure of Type Six Secretion System protein
分子名称: Uncharacterized protein
著者Jobichen, C, Sivaraman, J.
登録日2014-07-17
公開日2015-03-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Extended Loop Region of Hcp1 is Critical for the Assembly and Function of Type VI Secretion System in Burkholderia pseudomallei.
Sci Rep, 5, 2015
3WFN
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BU of 3wfn by Molmil
Crystal Structure of Nav1.6 IQ motif in complex with apo-CaM
分子名称: Calmodulin, Sodium channel protein type 8 subunit alpha
著者Chichili, V.P.R, Sivaraman, J.
登録日2013-07-23
公開日2013-08-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for the Modulation of the Neuronal Voltage-Gated Sodium Channel NaV1.6 by Calmodulin
Sci Rep, 3, 2013

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