4EDY
 
 | | Crystal structure of hH-PGDS with water displacing inhibitor | | 分子名称: | 4-[2-(hydroxymethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide, DIMETHYL SULFOXIDE, GLUTATHIONE, ... | | 著者 | Day, J.E, Thorarensen, A, Trujillo, J.I, Kiefer, J.R. | | 登録日 | 2012-03-27 | | 公開日 | 2012-10-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters.
Bioorg.Med.Chem.Lett., 22, 2012
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4FDF
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2MJL
 | | Solution structure of peptidyl-tRNA hyrolase from Vibrio cholerae | | 分子名称: | Peptidyl-tRNA hydrolase | | 著者 | Kabra, A, Shahid, S, Yadav, R, Pulavarti, S, Shukla, V.K, Arora, A. | | 登録日 | 2014-01-11 | | 公開日 | 2015-01-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of peptidyl-tRNA hydrolase from Vibrio cholerae
To be Published
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2NPB
 | | NMR solution structure of mouse SelW | | 分子名称: | Selenoprotein W | | 著者 | Aachmann, F.L, Fomenko, D.E, Soragni, A, Gladyshev, V.N, Dikiy, A. | | 登録日 | 2006-10-27 | | 公開日 | 2006-11-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of selenoprotein W and NMR analysis of its interaction with 14-3-3 proteins
J.Biol.Chem., 282, 2007
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2KGY
 | | Solution structure of Rv0603 protein from Mycobacterium tuberculosis H37Rv | | 分子名称: | POSSIBLE EXPORTED PROTEIN | | 著者 | Tripathi, S, Pulavarti, S.V.S.R.K, Pathak, P.P, Meher, A.K, Jain, A, Arora, A. | | 登録日 | 2009-03-23 | | 公開日 | 2010-03-31 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Rv0603 protein from Mycobacterium tuberculosis H37Rv
To be Published
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2L72
 | | Solution structure and dynamics of ADF from Toxoplasma gondii (TgADF) | | 分子名称: | Actin depolymerizing factor, putative | | 著者 | Pathak, P.P, Shukla, V.K, Yadav, R, Jain, A, Srivastava, S, Tripathi, S, Pulavarti, S.V.S.R.K, Arora, A. | | 登録日 | 2010-12-01 | | 公開日 | 2011-08-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of ADF from Toxoplasma gondii
J.Struct.Biol., 176, 2011
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2NCH
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2MV2
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2Z9T
 | | Crystal structure of the human beta-2 microglobulin mutant W60G | | 分子名称: | Beta-2-microglobulin | | 著者 | Ricagno, S, Bolognesi, M, Bellotti, V, Corazza, A, Rennella, E, Gural, D, Mimmi, M.C, Betto, E, Pucillo, C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M. | | 登録日 | 2007-09-26 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties
J.Mol.Biol., 378, 2008
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2K27
 | | Solution structure of Human Pax8 Paired Box Domain | | 分子名称: | Paired box protein Pax-8 | | 著者 | Codutti, L, Esposito, G, Corazza, A, Fogolari, F, Tell, G, Vascotto, C, van Ingen, H, Boelens, R, Viglino, P, Quadrifoglio, F. | | 登録日 | 2008-03-26 | | 公開日 | 2008-09-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein Family.
J.Biol.Chem., 283, 2008
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2HDN
 | | Trypsin-modified Elongation Factor Tu in complex with tetracycline at 2.8 Angstrom resolution | | 分子名称: | Elongation factor EF-Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F. | | 登録日 | 2006-06-20 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
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2MW5
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2MOT
 | | Backbone Structure of Actin Depolymerizing Factor (ADF) of Toxoplasma gondii Based on Prot3DNMR Approach | | 分子名称: | Actin depolymerizing factor ADF | | 著者 | Kumar, D, Raikwal, N, Raval, I, Jaiswal, N, Shukla, V, Arora, A. | | 登録日 | 2014-05-05 | | 公開日 | 2015-05-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Prot3DNMR: A Simple and Swift Strategy for Backbone Structure Determination of Proteins by NMR
To be Published
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2HCJ
 | | Trypsin-modified Elongation Factor Tu in complex with tetracycline | | 分子名称: | GLYOXYLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F. | | 登録日 | 2006-06-16 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
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2VB5
 | | Solution structure of W60G mutant of human beta2-microglobulin | | 分子名称: | BETA-2-MICROGLOBULIN | | 著者 | Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V. | | 登録日 | 2007-09-06 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties.
J.Mol.Biol., 378, 2008
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3LQY
 | | Crystal structure of putative isochorismatase hydrolase from Oleispira antarctica | | 分子名称: | GLYCEROL, putative isochorismatase hydrolase | | 著者 | Goral, A, Chruszcz, M, Kagan, O, Cymborowski, M, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-02-10 | | 公開日 | 2010-03-16 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of a putative isochorismatase hydrolase from Oleispira antarctica.
J.Struct.Funct.Genom., 13, 2012
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2BJE
 | | Acylphosphatase from Sulfolobus solfataricus. Monclinic P21 space group | | 分子名称: | ACYLPHOSPHATASE, CHLORIDE ION, SULFATE ION | | 著者 | Rosano, C, Zuccotti, S. | | 登録日 | 2005-02-02 | | 公開日 | 2005-11-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
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2BJD
 | | Sulfolobus Solfataricus Acylphosphatase. Triclinic space group | | 分子名称: | ACYLPHOSPHATASE, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Rosano, C, Zuccotti, S, Bolognesi, M. | | 登録日 | 2005-02-02 | | 公開日 | 2005-11-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
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5TTU
 | | Jak3 with covalent inhibitor 7 | | 分子名称: | 1-[(3aR,7aR)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)octahydro-6H-pyrrolo[2,3-c]pyridin-6-yl]propan-1-one, SULFATE ION, Tyrosine-protein kinase JAK3 | | 著者 | Vajdos, F.F. | | 登録日 | 2016-11-04 | | 公開日 | 2017-02-22 | | 最終更新日 | 2017-03-22 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans.
J. Med. Chem., 60, 2017
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5TTS
 | | Jak3 with covalent inhibitor 4 | | 分子名称: | 1-{(3R)-3-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one, Tyrosine-protein kinase JAK3 | | 著者 | Vajdos, F.F. | | 登録日 | 2016-11-04 | | 公開日 | 2017-02-22 | | 最終更新日 | 2017-03-22 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans.
J. Med. Chem., 60, 2017
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5TTV
 | | Jak3 with covalent inhibitor 6 | | 分子名称: | N-[3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]propanamide, Tyrosine-protein kinase JAK3 | | 著者 | Vajdos, F.F. | | 登録日 | 2016-11-04 | | 公開日 | 2017-02-22 | | 最終更新日 | 2017-03-22 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans.
J. Med. Chem., 60, 2017
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5LKA
 | | Crystal structure of haloalkane dehalogenase LinB 140A+143L+177W+211L mutant (LinB86) from Sphingobium japonicum UT26 at 1.3 A resolution | | 分子名称: | Haloalkane dehalogenase, THIOCYANATE ION | | 著者 | Degtjarik, O, Rezacova, P, Iermak, I, Chaloupkova, R, Damborsky, J, Kuta Smatanova, I. | | 登録日 | 2016-07-21 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.298 Å) | | 主引用文献 | Engineering a de novo transport tunnel.
Acs Catalysis, 2016
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4UU4
 | | Crystal structure of LptH, the LptA homologous periplasmic component of the conserved lipopolysaccharide transport device from Pseudomonas aeruginosa | | 分子名称: | PERIPLASMIC LIPOPOLYSACCHARIDE TRANSPORT PROTEIN LPTH | | 著者 | Bollati, M, Villa, R, Gourlay, L.J, Barbiroli, A, Deho, G, Benedet, M, Polissi, A, Martorana, A, Sperandeo, P, Bolognesi, M, Nardini, M. | | 登録日 | 2014-07-24 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.751 Å) | | 主引用文献 | Crystal Structure of Lpth, the Periplasmic Component of the Lipopolysaccharide Transport Machinery from Pseudomonas Aeruginosa.
FEBS J., 282, 2015
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6DB3
 | | JAK3 with Cyanamide CP23 | | 分子名称: | Tyrosine-protein kinase JAK3, [(1S)-1-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]cyanamide | | 著者 | Vajdos, F.F. | | 登録日 | 2018-05-02 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors.
J. Med. Chem., 61, 2018
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6DUD
 | | JAK3 with cyanamide CP12 | | 分子名称: | N-[(1S)-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]imidoformamide, SULFATE ION, Tyrosine-protein kinase JAK3 | | 著者 | Vajdos, F.F. | | 登録日 | 2018-06-20 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors.
J. Med. Chem., 61, 2018
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