6H95
 
 | | AlbA, albicidin resistance protein | | 分子名称: | Albicidin resistance protein | | 著者 | Koehnke, J, Sikandar, A. | | 登録日 | 2018-08-03 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA.
J.Am.Chem.Soc., 140, 2018
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6HAI
 | | AlbAM131A mutant in complex with albicidin , albicidin resistance protein | | 分子名称: | 4-[[4-[[4-[(3~{S})-3-[[4-[[(~{E})-3-(4-hydroxyphenyl)-2-methyl-prop-2-enoyl]amino]phenyl]carbonylamino]-2,5-bis(oxidanylidene)pyrrolidin-1-yl]phenyl]carbonylamino]-3-methoxy-2-oxidanyl-phenyl]carbonylamino]-3-methoxy-2-oxidanyl-benzoic acid, Albicidin resistance protein, SULFATE ION | | 著者 | Koehnke, J, Sikandar, A. | | 登録日 | 2018-08-07 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA.
J.Am.Chem.Soc., 140, 2018
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6H97
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8ADG
 | | Cryo-EM structure of Darobactin 22 bound BAM complex | | 分子名称: | Darobactin 22, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | | 著者 | Yuan, B, Marlovits, T.C. | | 登録日 | 2022-07-08 | | 公開日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Darobactins Exhibiting Superior Antibiotic Activity by Cryo-EM Structure Guided Biosynthetic Engineering.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8A2N
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8ADI
 | | Cryo-EM structure of Darobactin 9 bound BAM complex | | 分子名称: | Darobactin 9, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | | 著者 | Yuan, B, Marlovits, T.C. | | 登録日 | 2022-07-08 | | 公開日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Darobactins Exhibiting Superior Antibiotic Activity by Cryo-EM Structure Guided Biosynthetic Engineering.
Angew.Chem.Int.Ed.Engl., 62, 2023
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5HU7
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5LHJ
 | | Bottromycin maturation enzyme BotP | | 分子名称: | CHLORIDE ION, GLYCEROL, Leucine aminopeptidase 2, ... | | 著者 | Koehnke, J, Mann, G. | | 登録日 | 2016-07-12 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structure and Substrate Recognition of the Bottromycin Maturation Enzyme BotP.
Chembiochem, 17, 2016
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5N5D
 | | Crystal Structure of the O-Methyltransferase TomG from Streptomyces achromogenes involved in Tomaymycin synthesis in complex with SAM | | 分子名称: | (R,R)-2,3-BUTANEDIOL, GLYCEROL, Methyltransferase, ... | | 著者 | Pippel, J, Blankenfeldt, W. | | 登録日 | 2017-02-13 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Total Biosynthesis of the Pyrrolo[4,2]benzodiazepine Scaffold Tomaymycin on an In Vitro Reconstituted NRPS System.
Cell Chem Biol, 24, 2017
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5LHK
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6ET1
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6ET2
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6ET0
 | | Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1) | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... | | 著者 | Witzgall, F, Blankenfeldt, W. | | 登録日 | 2017-10-25 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC.
Chembiochem, 19, 2018
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6ESZ
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6ET3
 | | Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4) | | 分子名称: | (R,R)-2,3-BUTANEDIOL, PqsB, PqsC, ... | | 著者 | Witzgall, F, Blankenfeldt, W. | | 登録日 | 2017-10-25 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC.
Chembiochem, 19, 2018
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6ETO
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3GSB
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6QRI
 | | Structure of rabbit G-actin in complex with chivosazole A | | 分子名称: | (2~{R},3~{R},5~{S},6~{E},8~{E},10~{Z},12~{S},13~{R},16~{Z},18~{E},20~{Z},22~{E},24~{R},25~{S},26~{E},28~{Z})-13-[(2~{S},3~{S},5~{S})-3,5-bis(oxidanyl)hexan-2-yl]-25-[(2~{R},3~{R},4~{S},5~{R},6~{R})-3,4-dimethoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-3-methoxy-2,12,22,24-tetramethyl-5-oxidanyl-14,32-dioxa-33-azabicyclo[28.2.1]tritriaconta-1(33),6,8,10,16,18,20,22,26,28,30-undecaen-15-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Schneider, S, Wang, S, Zahler, S. | | 登録日 | 2019-02-19 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Chivosazole A Modulates Protein-Protein Interactions of Actin.
J.Nat.Prod., 82, 2019
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6RYO
 | | Bacterial membrane enzyme structure by the in meso method at 1.9 A resolution | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, GLYCEROL, ... | | 著者 | Huang, C.Y, Olatunji, S, Bailey, J, Yu, X, Olieric, V, Wang, M, Caffrey, M. | | 登録日 | 2019-06-11 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.924 Å) | | 主引用文献 | Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin.
Nat Commun, 11, 2020
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6RYP
 | | Bacterial membrane enzyme structure by the in meso method at 2.3 A resolution | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Lipoprotein signal peptidase, ... | | 著者 | Huang, C.Y, Olatunji, S, Bailey, J, Yu, X, Olieric, V, Wang, M, Caffrey, M. | | 登録日 | 2019-06-11 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin.
Nat Commun, 11, 2020
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6RX4
 | | THE STRUCTURE OF BD OXIDASE FROM ESCHERICHIA COLI | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome bd-I ubiquinol oxidase subunit 1, ... | | 著者 | Rasmussen, T, Boettcher, B, Thesseling, A, Friedrich, T. | | 登録日 | 2019-06-07 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Homologous bd oxidases share the same architecture but differ in mechanism.
Nat Commun, 10, 2019
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5O22
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5O28
 | | E. coli FolD apo | | 分子名称: | Bifunctional protein FolD | | 著者 | Koehnke, J, Sikandar, A. | | 登録日 | 2017-05-19 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD.
Nat Commun, 8, 2017
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5O2A
 | | FolD Q98H | | 分子名称: | Bifunctional protein FolD | | 著者 | Koehnke, J, Sikandar, A. | | 登録日 | 2017-05-19 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD.
Nat Commun, 8, 2017
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1BT4
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