5GHM
 
 | | Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 7.0 | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION | | 著者 | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | | 登録日 | 2016-06-20 | | 公開日 | 2017-01-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
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5GHQ
 | | Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP under high concentrations of 2-oxo-dATP | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | | 著者 | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | | 登録日 | 2016-06-20 | | 公開日 | 2017-01-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.181 Å) | | 主引用文献 | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
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5GHJ
 | | Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | | 著者 | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | | 登録日 | 2016-06-20 | | 公開日 | 2017-01-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
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5GHP
 | | Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION | | 著者 | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | | 登録日 | 2016-06-20 | | 公開日 | 2017-01-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.192 Å) | | 主引用文献 | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
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5WS7
 | | Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 2-oxo-dATP | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | | 著者 | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | | 登録日 | 2016-12-05 | | 公開日 | 2017-01-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
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6ITZ
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6IU1
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5B36
 | | Crystal Structure of the O-Phosphoserine Sulfhydrylase from Aeropyrum pernix Complexed with Cysteine | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Nakamura, T, Takeda, E, Kawai, Y, Kataoka, M, Ishikawa, K. | | 登録日 | 2016-02-10 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Role of F225 in O-phosphoserine sulfhydrylase from Aeropyrum pernix K1
Extremophiles, 20, 2016
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5B3A
 | | Crystal Structure of O-Phoshoserine Sulfhydrylase from Aeropyrum pernix in Complexed with the alpha-Aminoacrylate Intermediate | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Protein CysO | | 著者 | Nakamura, T, Takeda, E, Kawai, Y, Kataoka, M, Ishikawa, K. | | 登録日 | 2016-02-12 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Role of F225 in O-phosphoserine sulfhydrylase from Aeropyrum pernix K1
Extremophiles, 20, 2016
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6LCS
 | | Crystal structure of 73MuL9 Fv-clasp fragment in complex with GA-pyridine analogue | | 分子名称: | (2~{S})-6-[4-(hydroxymethyl)-3-oxidanyl-pyridin-1-ium-1-yl]-2-(phenylmethoxycarbonylamino)hexanoic acid, PHOSPHATE ION, VH-SARAH, ... | | 著者 | Nakamura, T, Takagi, J, Yamagata, Y, Morioka, H. | | 登録日 | 2019-11-19 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular recognition of a single-chain Fv antibody specific for GA-pyridine, an advanced glycation end-product (AGE), elucidated using biophysical techniques and synthetic antigen analogues.
J.Biochem., 170, 2021
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3WL3
 | | N,N'-diacetylchitobiose deacetylase from Pyrococcus horikoshii | | 分子名称: | GLYCEROL, PHOSPHATE ION, Putative uncharacterized protein PH0499, ... | | 著者 | Nakamura, T, Niiyama, M, Hashimoto, W, Uegaki, K. | | 登録日 | 2013-11-07 | | 公開日 | 2014-05-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Expression from engineered Escherichia coli chromosome and crystallographic study of archaeal N,N'-diacetylchitobiose deacetylase
Febs J., 281, 2014
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3WL4
 | | N,N'-diacetylchitobiose deacetylase (Se-derivative) from Pyrococcus furiosus | | 分子名称: | CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Nakamura, T, Niiyama, M, Hashimoto, W, Uegaki, K. | | 登録日 | 2013-11-07 | | 公開日 | 2014-05-07 | | 最終更新日 | 2014-08-20 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Expression from engineered Escherichia coli chromosome and crystallographic study of archaeal N,N'-diacetylchitobiose deacetylase
Febs J., 281, 2014
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2CZN
 | | Solution structure of the chitin-binding domain of hyperthermophilic chitinase from pyrococcus furiosus | | 分子名称: | chitinase | | 著者 | Uegaki, T, Ikegami, T, Nakamura, T, Hagihara, Y, Mine, S, Inoue, T, Matsumura, H, Ataka, M, Ishikawa, K. | | 登録日 | 2005-07-13 | | 公開日 | 2006-07-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Tertiary structure and carbohydrate recognition by the chitin-binding domain of a hyperthermophilic chitinase from Pyrococcus furiosus.
J.Mol.Biol., 381, 2008
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2CWR
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8GR9
 | | Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomyces cerevisiae in complex with oxaloacetate and coenzyme-A | | 分子名称: | CHLORIDE ION, COENZYME A, Citrate synthase, ... | | 著者 | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | | 登録日 | 2022-09-01 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
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8GR8
 | | Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomycescerevisiae | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Citrate synthase, ... | | 著者 | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | | 登録日 | 2022-09-01 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
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8GRE
 | | F-box protein in complex with skp1(FL) and substrate | | 分子名称: | Citrate synthase, E3 ubiquitin ligase complex SCF subunit, F-box protein UCC1, ... | | 著者 | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | | 登録日 | 2022-09-01 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
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8GQZ
 | | Crystal structure of mitochondrial citrate synthase (Cit1) from Saccharomyces cerevisiae | | 分子名称: | ACETATE ION, CHLORIDE ION, Citrate synthase, ... | | 著者 | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | | 登録日 | 2022-08-31 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
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8GRF
 | | Crystal structure of F-box protein in the ternary complex with adaptor protein Skp1(DL) and its substrate | | 分子名称: | 1,2-ETHANEDIOL, Citrate synthase, E3 ubiquitin ligase complex SCF subunit, ... | | 著者 | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | | 登録日 | 2022-09-01 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
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3NG5
 | | Crystal Structure of V30M transthyretin complexed with (-)-epigallocatechin gallate (EGCG) | | 分子名称: | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, GLYCEROL, Transthyretin | | 著者 | Miyata, M, Nakamura, T, Ikemizu, S, Chirifu, M, Yamagata, Y, Kai, H. | | 登録日 | 2010-06-11 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of green tea polyphenol(-)-epigallocatechin gallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site
Biochemistry, 2010
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8HLA
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8HH0
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5LAO
 | | S-nitrosylated 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Maslennikov, I, Kwiatkowski, W, Choe, S, Lipton, S.A, Guntert, P, Riek, R. | | 登録日 | 2016-06-14 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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5LAM
 | | Refined 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Maslennikov, I, Kwiatkowski, W, Choe, S, Lipton, S.A, Guntert, P, Riek, R. | | 登録日 | 2016-06-14 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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5HBQ
 | | C63D mutant of the rhodanese domain of YgaP | | 分子名称: | CHLORIDE ION, Inner membrane protein YgaP, SODIUM ION | | 著者 | Eichmann, C, Tzitzilonis, C, Nakamura, T, Kwiatkowski, W, Maslennikov, I, Choe, S, Lipton, S.A, Riek, R. | | 登録日 | 2016-01-02 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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