5L5U
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![BU of 5l5u by Molmil](/molmil-images/mine/5l5u) | Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 | 分子名称: | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2016-05-28 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i. EMBO J., 35, 2016
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5L69
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![BU of 5l69 by Molmil](/molmil-images/mine/5l69) | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 16 | 分子名称: | (2~{S})-3-(1~{H}-indol-3-yl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2016-05-28 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i. EMBO J., 35, 2016
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5L61
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![BU of 5l61 by Molmil](/molmil-images/mine/5l61) | |
5L63
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![BU of 5l63 by Molmil](/molmil-images/mine/5l63) | Yeast 20S proteasome with human beta5c (1-138) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 | 分子名称: | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2016-05-28 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i. EMBO J., 35, 2016
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5L5F
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![BU of 5l5f by Molmil](/molmil-images/mine/5l5f) | |
5L5Z
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![BU of 5l5z by Molmil](/molmil-images/mine/5l5z) | |
5L6C
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![BU of 5l6c by Molmil](/molmil-images/mine/5l6c) | |
5L5B
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![BU of 5l5b by Molmil](/molmil-images/mine/5l5b) | |
5L5W
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![BU of 5l5w by Molmil](/molmil-images/mine/5l5w) | |
5L54
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![BU of 5l54 by Molmil](/molmil-images/mine/5l54) | Yeast 20S proteasome in complex with epoxyketone inhibitor 16 | 分子名称: | (2~{S})-3-(1~{H}-indol-3-yl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2016-05-27 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i. EMBO J., 35, 2016
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5L5T
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![BU of 5l5t by Molmil](/molmil-images/mine/5l5t) | Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 16 | 分子名称: | (2~{S})-3-(1~{H}-indol-3-yl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2016-05-28 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i. EMBO J., 35, 2016
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5L68
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![BU of 5l68 by Molmil](/molmil-images/mine/5l68) | |
5L55
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![BU of 5l55 by Molmil](/molmil-images/mine/5l55) | |
5L5R
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![BU of 5l5r by Molmil](/molmil-images/mine/5l5r) | |
5L67
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![BU of 5l67 by Molmil](/molmil-images/mine/5l67) | |
5L52
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![BU of 5l52 by Molmil](/molmil-images/mine/5l52) | |
5L5S
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![BU of 5l5s by Molmil](/molmil-images/mine/5l5s) | |
5L6A
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![BU of 5l6a by Molmil](/molmil-images/mine/5l6a) | Yeast 20S proteasome with mouse beta5i (1-138) and mouse beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 | 分子名称: | (2~{S})-3-(4-methoxyphenyl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2016-05-28 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i. EMBO J., 35, 2016
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5L5J
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![BU of 5l5j by Molmil](/molmil-images/mine/5l5j) | |
5L62
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![BU of 5l62 by Molmil](/molmil-images/mine/5l62) | Yeast 20S proteasome with human beta5c (1-138) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 16 | 分子名称: | (2~{S})-3-(1~{H}-indol-3-yl)-~{N}-[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{R})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2016-05-28 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i. EMBO J., 35, 2016
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5L5E
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![BU of 5l5e by Molmil](/molmil-images/mine/5l5e) | |
5L5Y
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![BU of 5l5y by Molmil](/molmil-images/mine/5l5y) | |
5LTT
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![BU of 5ltt by Molmil](/molmil-images/mine/5ltt) | |
4Y6A
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![BU of 4y6a by Molmil](/molmil-images/mine/4y6a) | |
4Y80
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![BU of 4y80 by Molmil](/molmil-images/mine/4y80) | Yeast 20S proteasome in complex with Ac-LAI-ep | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAI-ep, CHLORIDE ION, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2015-02-16 | 公開日 | 2015-06-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
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