3WGU
| Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C. | 登録日 | 2013-08-09 | 公開日 | 2013-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state Nature, 502, 2013
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1OMZ
| crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) in complex with UDPGalNAc | 分子名称: | 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, ... | 著者 | Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M. | 登録日 | 2003-02-26 | 公開日 | 2003-04-22 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2),
a member of the exostosin gene family involved in heparan sulfate biosynthesis J.Biol.Chem., 278, 2003
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1OMX
| Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) | 分子名称: | 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2 | 著者 | Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M. | 登録日 | 2003-02-26 | 公開日 | 2003-04-22 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis J.Biol.Chem., 278, 2003
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1CP8
| NMR STRUCTURE OF DNA (5'-D(TTGGCCAA)2-3') COMPLEXED WITH NOVEL ANTITUMOR DRUG UCH9 | 分子名称: | 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYDROXY-7-(SEC-BUTYL)-ANTHRACENE, DNA (5'-D(P*TP*TP*GP*GP*CP*CP*AP*A)-3'), MAGNESIUM ION, ... | 著者 | Katahira, R, Katahira, M, Yamashita, Y, Ogawa, H, Kyogoku, Y, Yoshida, M. | 登録日 | 1999-06-11 | 公開日 | 1999-07-01 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the novel antitumor drug UCH9 complexed with d(TTGGCCAA)2 as determined by NMR. Nucleic Acids Res., 26, 1998
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1ON6
| Crystal structure of mouse alpha-1,4-N-acetylhexosaminotransferase (EXTL2) in complex with UDPGlcNAc | 分子名称: | 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, ... | 著者 | Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M. | 登録日 | 2003-02-27 | 公開日 | 2003-04-22 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis J.Biol.Chem., 278, 2003
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1FGG
| CRYSTAL STRUCTURE OF 1,3-GLUCURONYLTRANSFERASE I (GLCAT-I) COMPLEXED WITH GAL-GAL-XYL, UDP, AND MN2+ | 分子名称: | GLUCURONYLTRANSFERASE I, MANGANESE (II) ION, UNKNOWN ATOM OR ION, ... | 著者 | Pedersen, L.C, Tsuchida, K, Kitagawa, H, Sugahara, K, Darden, T.A. | 登録日 | 2000-07-28 | 公開日 | 2001-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I. J.Biol.Chem., 275, 2000
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3CU0
| human beta 1,3-glucuronyltransferase I (GlcAT-I) in complex with UDP and GAL-GAL(6-SO4)-XYL(2-PO4)-O-SER | 分子名称: | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3, MANGANESE (II) ION, SULFATE ION, ... | 著者 | Tone, Y, Pedersen, L.C, Yamamoto, T, Kitagawa, H, Nishihara-Shimizu, J, Tamura, J, Negishi, M, Sugahara, K. | 登録日 | 2008-04-15 | 公開日 | 2008-05-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 2-o-phosphorylation of xylose and 6-o-sulfation of galactose in the protein linkage region of glycosaminoglycans influence the glucuronyltransferase-I activity involved in the linkage region synthesis. J.Biol.Chem., 283, 2008
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2SIC
| REFINED CRYSTAL STRUCTURE OF THE COMPLEX OF SUBTILISIN BPN' AND STREPTOMYCES SUBTILISIN INHIBITOR AT 1.8 ANGSTROMS RESOLUTION | 分子名称: | CALCIUM ION, STREPTOMYCES SUBTILISIN INHIBITOR (SSI), SUBTILISIN BPN' | 著者 | Mitsui, Y, Takeuchi, Y, Hirono, S, Akagawa, H, Nakamura, K.T. | 登録日 | 1991-04-01 | 公開日 | 1993-04-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Refined crystal structure of the complex of subtilisin BPN' and Streptomyces subtilisin inhibitor at 1.8 A resolution. J.Mol.Biol., 221, 1991
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7VMN
| Structure of recombinant RyR2 (EGTA dataset, class 2, closed state) | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | 著者 | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | 登録日 | 2021-10-09 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMO
| Structure of recombinant RyR2 (Ca2+ dataset, class 1, open state) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | 著者 | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | 登録日 | 2021-10-09 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMP
| Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | 著者 | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | 登録日 | 2021-10-09 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMQ
| Structure of recombinant RyR2 (Ca2+ dataset, class 3, open state) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | 著者 | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | 登録日 | 2021-10-09 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations Nat Commun, 13, 2022
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7VMM
| Structure of recombinant RyR2 (EGTA dataset, class 1, closed state) | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | 著者 | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | 登録日 | 2021-10-09 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMS
| Structure of recombinant RyR2 mutant K4593A (Ca2+ dataset) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | 著者 | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | 登録日 | 2021-10-09 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations Nat Commun, 13, 2022
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7VMR
| Structure of recombinant RyR2 mutant K4593A (EGTA dataset) | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | 著者 | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | 登録日 | 2021-10-09 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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3W5B
| Crystal structure of the recombinant SERCA1a (calcium pump of fast twitch skeletal muscle) in the E1.Mg2+ state | 分子名称: | 2',3'-O-[(1r)-2,4,6-trinitrocyclohexa-2,5-diene-1,1-diyl]adenosine 5'-(dihydrogen phosphate), MAGNESIUM ION, PHOSPHATIDYLETHANOLAMINE, ... | 著者 | Toyoshima, C, Iwasawa, S, Ogawa, H, Hirata, A, Tsueda, J, Inesi, G. | 登録日 | 2013-01-27 | 公開日 | 2013-03-06 | 最終更新日 | 2013-03-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state. Nature, 495, 2013
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3W5C
| Crystal structure of the calcium pump in the E2 state free from exogenous inhibitors | 分子名称: | PHOSPHATIDYLETHANOLAMINE, SERCA1a, SODIUM ION | 著者 | Toyoshima, C, Iwasawa, S, Ogawa, H, Hirata, A, Tsueda, J, Inesi, G. | 登録日 | 2013-01-27 | 公開日 | 2013-03-06 | 最終更新日 | 2013-03-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state. Nature, 495, 2013
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3WGV
| Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C. | 登録日 | 2013-08-09 | 公開日 | 2013-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state Nature, 502, 2013
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2ZBG
| Calcium pump crystal structure with bound AlF4 and TG in the absence of calcium | 分子名称: | MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Toyoshima, C, Ogawa, H, Norimatsu, Y. | 登録日 | 2007-10-20 | 公開日 | 2007-12-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ZBE
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2ZBF
| Calcium pump crystal structure with bound BeF3 and TG in the absence of calcium | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | Toyoshima, C, Ogawa, H, Norimatsu, Y. | 登録日 | 2007-10-20 | 公開日 | 2007-12-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ZFA
| Structure of Lactate Oxidase at pH4.5 from AEROCOCCUS VIRIDANS | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, Lactate oxidase | 著者 | Furuichi, M, Balasundaresan, D, Suzuki, N, Yoshida, Y, Minagawa, H, Kaneko, H, Waga, I, Kumar, P.K.R, Mizuno, H. | 登録日 | 2007-12-26 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | X-ray structures of Aerococcus viridans lactate oxidase and its complex with D-lactate at pH 4.5 show an alpha-hydroxyacid oxidation mechanism J.Mol.Biol., 378, 2008
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1XWF
| K185N mutated S-adenosylhomocysteine hydrolase | 分子名称: | ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Yamada, T, Takata, Y, Komoto, J, Gomi, T, Ogawa, H, Fujioka, M, Takusagawa, F. | 登録日 | 2004-11-01 | 公開日 | 2005-09-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Catalytic mechanism of S-adenosylhomocysteine hydrolase: Roles of His 54, Asp130, Glu155, Lys185, and Aspl89. Int.J.Biochem.Cell Biol., 37, 2005
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7D94
| Crystal Structure of the Na+,K+-ATPase in the E2P state with bound one Mg2+ and one Rb+ in the presence of bufalin | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kanai, R, Cornelius, F, Ogawa, H, Motoyama, K, Vilsen, B, Toyoshima, C. | 登録日 | 2020-10-12 | 公開日 | 2021-01-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state. Proc.Natl.Acad.Sci.USA, 118, 2021
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7D91
| Crystal Structure of the Na+,K+-ATPase in the E2P state with bound Mg2+ (P4(3)2(1)2 symmetry) | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kanai, R, Cornelius, F, Ogawa, H, Motoyama, K, Vilsen, B, Toyoshima, C. | 登録日 | 2020-10-12 | 公開日 | 2021-01-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state. Proc.Natl.Acad.Sci.USA, 118, 2021
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