3BOE
| Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 with acetate (CDCA1-R2) | 分子名称: | ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase | 著者 | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | 登録日 | 2007-12-17 | 公開日 | 2008-01-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
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3BOJ
| Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 without bound metal (CDCA1-R1) | 分子名称: | ACETATE ION, Cadmium-specific carbonic anhydrase | 著者 | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | 登録日 | 2007-12-17 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
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3BOH
| Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 with acetate (CDCA1-R1) | 分子名称: | ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase | 著者 | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | 登録日 | 2007-12-17 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
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2FP3
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2G4A
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1MR1
| Crystal Structure of a Smad4-Ski Complex | 分子名称: | Mothers against decapentaplegic homolog 4, Ski oncogene, ZINC ION | 著者 | Wu, J.-W, Krawitz, A.R, Chai, J, Li, W, Zhang, F, Luo, K, Shi, Y. | 登録日 | 2002-09-17 | 公開日 | 2003-01-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski: Insights on Ski-mediated Repression of TGF-beta Signaling Cell(Cambridge,Mass.), 111, 2002
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8Y6P
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5JNX
| The 6.6 A cryo-EM structure of the full-length human NPC1 in complex with the cleaved glycoprotein of Ebola virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... | 著者 | Gong, X, Qian, H.W, Zhou, X.H, Wu, J.P, Wan, T, Shi, Y, Gao, F, Zhou, Q, Yan, N. | 登録日 | 2016-05-01 | 公開日 | 2016-06-15 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (6.56 Å) | 主引用文献 | Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection Cell, 165, 2016
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8A9L
| Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies | 分子名称: | Alpha-synuclein, Unknown fragment | 著者 | Yang, Y, Shi, Y, Schweighauser, M, Zhang, X.J, Kotecha, A, Murzin, A.G, Garringer, H.J, Cullinane, P, Saito, Y, Foroud, T, Warner, T.T, Hasegawa, K, Vidal, R, Murayama, S, Revesz, T, Ghetti, B, Hasegawa, M, Lashley, T, Scheres, H.W.S, Goedert, M. | 登録日 | 2022-06-28 | 公開日 | 2022-08-31 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (2.16 Å) | 主引用文献 | Structures of alpha-synuclein filaments from human brains with Lewy pathology. Nature, 610, 2022
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8BQW
| Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy | 分子名称: | Alpha-synuclein, Unknown protein | 著者 | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | 登録日 | 2023-01-18 | 公開日 | 2023-02-22 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy. Acta Neuropathol, 145, 2023
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8BQV
| Cryo-EM structure of alpha-synuclein singlet filament from Juvenile-onset synucleinopathy | 分子名称: | Alpha-synuclein, Unknown protein | 著者 | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | 登録日 | 2023-01-18 | 公開日 | 2023-02-22 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy. Acta Neuropathol, 145, 2023
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5X4R
| Structure of the N-terminal domain (NTD) of MERS-CoV spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | 著者 | Yuan, Y, Zhang, Y, Qi, J, Shi, Y, Gao, G.F. | 登録日 | 2017-02-14 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5X58
| Prefusion structure of SARS-CoV spike glycoprotein, conformation 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5X5B
| Prefusion structure of SARS-CoV spike glycoprotein, conformation 2 | 分子名称: | Spike glycoprotein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5X59
| Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5X5C
| Prefusion structure of MERS-CoV spike glycoprotein, conformation 1 | 分子名称: | S protein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-24 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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4UIS
| The cryoEM structure of human gamma-Secretase complex | 分子名称: | GAMMA-SECRETASE, LYSOZYME | 著者 | Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y. | 登録日 | 2015-04-03 | 公開日 | 2015-06-10 | 最終更新日 | 2017-08-02 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural Basis of Human Gamma-Secretase Assembly. Proc.Natl.Acad.Sci.USA, 112, 2015
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4F23
| Influenza A virus hemagglutinin H16 HA0 structure with an alpha-helix conformation in the cleavage site: a potential drug target | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | 著者 | Lu, X, Shi, Y, Gao, F, Xiao, H, Qi, J, Gao, G.F. | 登録日 | 2012-05-07 | 公開日 | 2012-11-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage. J.Virol., 86, 2012
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8X52
| Cryo-EM structure of human gamma-secretase in complex with Abeta49 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | 登録日 | 2023-11-16 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase Science, 2024
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3U83
| Crystal structure of nectin-1 | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Poliovirus receptor-related protein 1 | 著者 | Zhang, N, Yan, J, Lu, G, Guo, Z, Fan, Z, Wang, J, Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2011-10-15 | 公開日 | 2012-03-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion. Nat Commun, 2, 2011
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8X53
| Cryo-EM structure of human gamma-secretase in complex with Abeta46 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | 登録日 | 2023-11-16 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase Science, 2024
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8X54
| Cryo-EM structure of human gamma-secretase in complex with APP-C99 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | 登録日 | 2023-11-16 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase Science, 2024
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3U82
| Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion | 分子名称: | Envelope glycoprotein D, Poliovirus receptor-related protein 1 | 著者 | Zhang, N, Yan, J, Lu, G, Guo, Z, Fan, Z, Wang, J, Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2011-10-15 | 公開日 | 2012-03-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.164 Å) | 主引用文献 | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion. Nat Commun, 2, 2011
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5XLP
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5WZK
| Structure of APUM23-deletion-of-insert-region-GGAAUUGACGG | 分子名称: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | 著者 | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-01-18 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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