2Q12
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2Q13
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7YSN
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7YSP
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7YSO
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7YSR
| GTPgammaS MT decorated with kinesin | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha chain, ... | 著者 | Zhou, J, Wang, H.-W. | 登録日 | 2022-08-12 | 公開日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insights into the mechanism of GTP initiation of microtubule assembly. Nat Commun, 14, 2023
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7YSQ
| GTPgammaS Tube decorated with kinesin | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha chain, ... | 著者 | Zhou, J, Wang, H.-W. | 登録日 | 2022-08-12 | 公開日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Structural insights into the mechanism of GTP initiation of microtubule assembly. Nat Commun, 14, 2023
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3V43
| Crystal structure of MOZ | 分子名称: | ACETATE ION, Histone H3.1, Histone acetyltransferase KAT6A, ... | 著者 | Qiu, Y, Li, F. | 登録日 | 2011-12-14 | 公開日 | 2012-06-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription Genes Dev., 26, 2012
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6LBS
| Crystal structure of yeast Stn1 | 分子名称: | KLLA0C11825p | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-19 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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6LBR
| Crystal structure of yeast Cdc13 and ssDNA | 分子名称: | KLLA0F20922p, Telomere single-strand DNA | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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6LBT
| Crystal structure of yeast Cdc13 and Stn1 | 分子名称: | GLYCEROL, KLLA0C11825p, KLLA0F20922p,KLLA0F20922p | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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6LBU
| Crystal structure of yeast Stn1 and Ten1 | 分子名称: | KLLA0C11825p, KLLA0E09417p | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-19 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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1X79
| Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5 | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADP-ribosylation factor binding protein GGA1, Rab GTPase binding effector protein 1, ... | 著者 | Zhu, G, Zhang, X.C. | 登録日 | 2004-08-13 | 公開日 | 2004-10-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5. EMBO J., 23, 2004
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7V2Y
| cryo-EM structure of yeast THO complex with Sub2 | 分子名称: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ... | 著者 | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | 登録日 | 2021-08-10 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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7V2W
| protomer structure from the dimer of yeast THO complex | 分子名称: | Protein TEX1, THO complex subunit 2, THO complex subunit HPR1, ... | 著者 | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | 登録日 | 2021-08-10 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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7YRG
| histone methyltransferase | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | 著者 | Li, H, Wang, W.Y. | 登録日 | 2022-08-09 | 公開日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1. Mol.Cell, 83, 2023
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7N7V
| Crystal structure of TtnM, a Fe(II)-alpha-ketoglutarate-dependent hydroxylase from the tautomycetin biosynthesis pathway in Streptomyces griseochromogenes at 2 A. | 分子名称: | CHLORIDE ION, FE (II) ION, Predicted hydroxylase | 著者 | Han, L, Xu, W, Ma, M, Miller, M.D, Shen, B, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2021-06-11 | 公開日 | 2022-07-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure of TtnM, a Fe(II)-alpha-ketoglutarate-dependent hydroxylase from the tautomycetin biosynthesis pathway in Streptomyces griseochromogenes. To Be Published
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3THB
| Structure of PLK1 kinase domain in complex with a benzolactam-derived inhibitor | 分子名称: | 9-chloro-2-({5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl}amino)-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepine-6-thi one, Serine/threonine-protein kinase PLK1, ZINC ION | 著者 | Sintchak, M.D. | 登録日 | 2011-08-18 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905). J.Med.Chem., 55, 2012
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1GH2
| Crystal structure of the catalytic domain of a new human thioredoxin-like protein | 分子名称: | THIOREDOXIN-LIKE PROTEIN | 著者 | Jin, J, Chen, X, Guo, Q, Yuan, J, Qiang, B, Rao, Z. | 登録日 | 2000-11-01 | 公開日 | 2001-05-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Crystal structure of the catalytic domain of a human thioredoxin-like protein. Eur.J.Biochem., 269, 2002
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5H19
| EED in complex with PRC2 allosteric inhibitor EED162 | 分子名称: | 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H. | 登録日 | 2016-10-08 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED PLoS ONE, 12, 2017
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8GUE
| Crystal Structure of narbomycin-bound cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P450 monooxygenase PikC, ... | 著者 | Li, G.B, Pan, Y.J, Li, S.Y, Gao, X. | 登録日 | 2022-09-11 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unnatural activities and mechanistic insights of cytochrome P450 PikC gained from site-specific mutagenesis by non-canonical amino acids. Nat Commun, 14, 2023
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5ZAZ
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5F59
| The crystal structure of MLL3 SET domain | 分子名称: | Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-04 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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5F6L
| The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L | 分子名称: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-06 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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5F5E
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