1A5Z
 
 | | LACTATE DEHYDROGENASE FROM THERMOTOGA MARITIMA (TMLDH) | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, CADMIUM ION, L-LACTATE DEHYDROGENASE, ... | | 著者 | Auerbach, G, Ostendorp, R, Prade, L, Korndoerfer, I, Dams, T, Huber, R, Jaenicke, R. | | 登録日 | 1998-02-18 | | 公開日 | 1999-03-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization.
Structure, 6, 1998
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1BD8
 | | STRUCTURE OF CDK INHIBITOR P19INK4D | | 分子名称: | P19INK4D CDK4/6 INHIBITOR | | 著者 | Baumgartner, R, Fernandez-Catalan, C, Winoto, A, Huber, R, Engh, R, Holak, T.A. | | 登録日 | 1998-05-12 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of human cyclin-dependent kinase inhibitor p19INK4d: comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16INK4a.
Structure, 6, 1998
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1AQW
 | | GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH GLUTATHIONE | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, GLUTATHIONE S-TRANSFERASE | | 著者 | Prade, L, Huber, R, Manoharan, T.H, Fahl, W.E, Reuter, W. | | 登録日 | 1997-08-03 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor.
Structure, 5, 1997
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1AQX
 | | GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH MEISENHEIMER COMPLEX | | 分子名称: | 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE | | 著者 | Prade, L, Huber, R, Manoharan, T.H, Fahl, W.E, Reuter, W. | | 登録日 | 1997-08-03 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor.
Structure, 5, 1997
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3JDW
 | | CRYSTAL STRUCTURE AND MECHANISM OF L-ARGININE: GLYCINE AMIDINOTRANSFERASE: A MITOCHONDRIAL ENZYME INVOLVED IN CREATINE BIOSYNTHESIS | | 分子名称: | L-ARGININE:GLYCINE AMIDINOTRANSFERASE, L-ornithine | | 著者 | Humm, A, Fritsche, E, Steinbacher, S, Huber, R. | | 登録日 | 1997-01-24 | | 公開日 | 1998-01-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.
EMBO J., 16, 1997
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2QZX
 | | Secreted aspartic proteinase (Sap) 5 from Candida albicans | | 分子名称: | Candidapepsin-5, Pepstatin | | 著者 | Lee, J.H, Ruge, E, Borelli, C, Maskos, K, Huber, R. | | 登録日 | 2007-08-17 | | 公開日 | 2008-07-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from Candida albicans.
Proteins, 72, 2008
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4W9Z
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1ALL
 | | ALLOPHYCOCYANIN | | 分子名称: | ALLOPHYCOCYANIN, PHYCOCYANOBILIN | | 著者 | Brejc, K, Ficner, R, Huber, R, Steinbacher, S. | | 登録日 | 1995-03-01 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Isolation, crystallization, crystal structure analysis and refinement of allophycocyanin from the cyanobacterium Spirulina platensis at 2.3 A resolution.
J.Mol.Biol., 249, 1995
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1CLW
 | | TAILSPIKE PROTEIN FROM PHAGE P22, V331A MUTANT | | 分子名称: | TAILSPIKE PROTEIN | | 著者 | Steinbacher, S, Baxa, U, Weintraub, A, Huber, R, Seckler, R. | | 登録日 | 1999-05-04 | | 公開日 | 1999-11-05 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutations improving the folding of phage P22 tailspike protein affect its receptor binding activity.
J.Mol.Biol., 293, 1999
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1AW9
 | | STRUCTURE OF GLUTATHIONE S-TRANSFERASE III IN APO FORM | | 分子名称: | CADMIUM ION, GLUTATHIONE S-TRANSFERASE III | | 著者 | Neuefeind, T, Huber, R, Reinemer, P, Knaeblein, J. | | 登録日 | 1997-10-13 | | 公開日 | 1998-10-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Cloning, sequencing, crystallization and X-ray structure of glutathione S-transferase-III from Zea mays var. mutin: a leading enzyme in detoxification of maize herbicides.
J.Mol.Biol., 274, 1997
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1BLI
 | | BACILLUS LICHENIFORMIS ALPHA-AMYLASE | | 分子名称: | ALPHA-AMYLASE, CALCIUM ION, SODIUM ION | | 著者 | Machius, M, Declerck, N, Huber, R, Wiegand, G. | | 登録日 | 1998-01-07 | | 公開日 | 1999-03-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Activation of Bacillus licheniformis alpha-amylase through a disorder-->order transition of the substrate-binding site mediated by a calcium-sodium-calcium metal triad.
Structure, 6, 1998
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1CTS
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4HTC
 | | THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ... | | 著者 | Tulinsky, A, Rydel, T.J, Bode, W, Huber, R. | | 登録日 | 1993-06-25 | | 公開日 | 1994-01-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Refined structure of the hirudin-thrombin complex.
J.Mol.Biol., 221, 1991
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2UX7
 | | Pseudoazurin with engineered amicyanin ligand loop, reduced form, pH 7.5 | | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Velarde, M, Huber, R, Yanagisawa, S, Dennison, C, Messerschmidt, A. | | 登録日 | 2007-03-27 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Influence of loop shortening on the metal binding site of cupredoxin pseudoazurin.
Biochemistry, 46, 2007
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2UX6
 | | Pseudoazurin with engineered amicyanin ligand loop, oxidized form, pH 7.5 | | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Velarde, M, Huber, R, Yanagisawa, S, Dennison, C, Messerschmidt, A. | | 登録日 | 2007-03-27 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Influence of Loop Shortening on the Metal Binding Site of Cupredoxin Pseudoazurin.
Biochemistry, 46, 2007
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1C7N
 | | CRYSTAL STRUCTURE OF CYSTALYSIN FROM TREPONEMA DENTICOLA CONTAINS A PYRIDOXAL 5'-PHOSPHATE COFACTOR | | 分子名称: | CYSTALYSIN, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Krupka, H.I, Huber, R, Holt, S.C, Clausen, T. | | 登録日 | 2000-03-16 | | 公開日 | 2000-07-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of cystalysin from Treponema denticola: a pyridoxal 5'-phosphate-dependent protein acting as a haemolytic enzyme.
EMBO J., 19, 2000
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2UXF
 | | Pseudoazurin with engineered amicyanin ligand loop, oxidized form, pH 5.5 | | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Velarde, M, Huber, R, Yanagisawa, S, Dennison, C, Messerschmidt, A. | | 登録日 | 2007-03-28 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Influence of Loop Shortening on the Metal Binding Site of Cupredoxin Pseudoazurin.
Biochemistry, 46, 2007
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2UXG
 | | Pseudoazurin with engineered amicyanin ligand loop, reduced form, pH 5.5 | | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Velarde, M, Huber, R, Yanagisawa, S, Dennison, C, Messerschmidt, A. | | 登録日 | 2007-03-28 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Influence of Loop Shortening on the Metal Binding Site of Cupredoxin Pseudoazurin.
Biochemistry, 46, 2007
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1C7O
 | | CRYSTAL STRUCTURE OF CYSTALYSIN FROM TREPONEMA DENTICOLA CONTAINS A PYRIDOXAL 5'-PHOSPHATE-L-AMINOETHOXYVINYLGLYCINE COMPLEX | | 分子名称: | (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, CYSTALYSIN | | 著者 | Krupka, H.I, Huber, R, Holt, S.C, Clausen, T. | | 登録日 | 2000-03-16 | | 公開日 | 2000-07-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of cystalysin from Treponema denticola: a pyridoxal 5'-phosphate-dependent protein acting as a haemolytic enzyme.
EMBO J., 19, 2000
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1D02
 | | CRYSTAL STRUCTURE OF MUNI RESTRICTION ENDONUCLEASE IN COMPLEX WITH COGNATE DNA | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*TP*TP*GP*GP*C)-3'), TYPE II RESTRICTION ENZYME MUNI | | 著者 | Deibert, M, Grazulis, S, Janulaitis, A, Siksnys, V, Huber, R. | | 登録日 | 1999-09-08 | | 公開日 | 2000-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of MunI restriction endonuclease in complex with cognate DNA at 1.7 A resolution.
EMBO J., 18, 1999
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4F7S
 | | Crystal structure of human CDK8/CYCC in the DMG-in conformation | | 分子名称: | 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ... | | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | | 登録日 | 2012-05-16 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4F7J
 | | Crystal structure of human CDK8/CYCC in complex with compound 3 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(2-hydroxyethyl)urea) | | 分子名称: | 1,2-ETHANEDIOL, 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(2-hydroxyethyl)urea, Cyclin-C, ... | | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | | 登録日 | 2012-05-16 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4F6U
 | | Crystal structure of human CDK8/CYCC in complex with compound 5 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea) | | 分子名称: | 1,2-ETHANEDIOL, 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea, Cyclin-C, ... | | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | | 登録日 | 2012-05-15 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4F6W
 | | Crystal structure of human CDK8/CYCC in complex with compound 1 (N-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-4-[2-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)ethyl]piperazine-1-carboxamide) | | 分子名称: | 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ... | | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | | 登録日 | 2012-05-15 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4QBY
 | | yCP in complex with BOC-ALA-ALA-ALA-CHO | | 分子名称: | BOC-ALA-ALA-ALA-CHO, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | | 著者 | Arciniega, M, Beck, P, Lange, O, Groll, M, Huber, R. | | 登録日 | 2014-05-09 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding.
Proc.Natl.Acad.Sci.USA, 111, 2014
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