Search by PDB author

Aurora A kinase bound to a highly selective imidazopyridine inhibitor
分子名称:	(S)-N-(1-(6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)acetamide, AURORA KINASE A
著者	Joshi, A, Kosmopoulou, M, Bayliss, R.
登録日	2013-07-19
公開日	2013-11-20
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (2.75 Å)
主引用文献	Aurora Isoform Selectivity: Design and Synthesis of Imidazo[4,5-B]Pyridine Derivatives as Highly Selective Inhibitors of Aurora-A Kinase in Cells. J.Med.Chem., 56, 2013

Crystal structure of V174M mutant of Aurora-A kinase
分子名称:	ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, CALCIUM ION
著者	Bibby, R.A, Bayliss, R.
登録日	2013-05-13
公開日	2014-03-26
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (2.499 Å)
主引用文献	Insights Into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification. Acs Chem.Biol., 8, 2013

CDK8-CYCC IN COMPLEX WITH [6-Hydroxy-3-(3-methyl-benzyl)-1H-indazol-5-yl]-((S)-3-hydroxy-pyrrolidin-1-yl)-methanone
分子名称:	1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ...
著者	Musil, D, Blagg, J, Schiemann, K.
登録日	2016-01-18
公開日	2016-04-27
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	CDK8-CYCC IN COMPLEX WITH [6-Hydroxy-3-(3-methyl-benzyl)-1H-indazol-5-yl]-((S)-3-hydroxy-pyrrolidin-1-yl)-methanone To Be Published