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3WF7
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BU of 3wf7 by Molmil
Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide
分子名称: 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WIO
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BU of 3wio by Molmil
Crystal structure of OSD14 in complex with hydroxy D-ring
分子名称: (5R)-5-hydroxy-3-methylfuran-2(5H)-one, Probable strigolactone esterase D14
著者Xue, Y.-L, Miyakawa, T, Hou, F, Qin, H.-M, Tanokura, M.
登録日2013-09-22
公開日2013-10-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular mechanism of strigolactone perception by DWARF14
Nat Commun, 4, 2013
3WO0
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BU of 3wo0 by Molmil
Crystal structure of Bacillus subtilis YwfE, an L-amino acid ligase, with bound ADP-Mg-Ala
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALANINE, Alanine-anticapsin ligase BacD, ...
著者Tsuda, T, Kojima, S.
登録日2013-12-19
公開日2014-05-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Single Mutation Alters the Substrate Specificity of l-Amino Acid Ligase
Biochemistry, 53, 2014
3WF5
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BU of 3wf5 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
分子名称: 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WO1
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BU of 3wo1 by Molmil
Crystal structure of Trp332Ala mutant YwfE, an L-amino acid ligase, with bound ADP-Mg-Ala
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALANINE, Alanine-anticapsin ligase BacD, ...
著者Tsuda, T, Kojima, S.
登録日2013-12-19
公開日2014-05-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Single Mutation Alters the Substrate Specificity of l-Amino Acid Ligase
Biochemistry, 53, 2014
3WF8
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BU of 3wf8 by Molmil
Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate
分子名称: 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3CC2
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BU of 3cc2 by Molmil
The Refined Crystal Structure of the Haloarcula Marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution with rrnA Sequence for the 23S rRNA and Genome-derived Sequences for r-Proteins
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Gurel, G, Blaha, G.
登録日2008-02-23
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
5I8N
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BU of 5i8n by Molmil
Solution Structure of human calcium-binding S100A9 (C3S) protein
分子名称: Protein S100-A9
著者Chang, C.-C, Chin, Y.
登録日2016-02-19
公開日2016-08-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Blocking the interaction between S100A9 and RAGE V domain using CHAPS molecule: A novel route to drug development against cell proliferation
Biochim.Biophys.Acta, 1864, 2016
7KEY
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BU of 7key by Molmil
Protein Tyrosine Phosphatase 1B, Apo
分子名称: ACETATE ION, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1
著者Battaile, K.P, Chirgadze, Y, Ruzanov, M, Romanov, V, Lam, K, Gordon, R, Lin, A, Lam, R, Pai, E, Chirgadze, N.
登録日2020-10-13
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.771 Å)
主引用文献Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058.
J.Biomol.Struct.Dyn., 2021
7JJC
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BU of 7jjc by Molmil
Crystal structure of neuropilin-1 b1 domain in complex with SARS-CoV-2 S1 C-end rule (CendR) peptide
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Neuropilin-1, ...
著者Chen, K.-E, Collins, B.M.
登録日2020-07-25
公開日2020-10-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Neuropilin-1 is a host factor for SARS-CoV-2 infection.
Science, 370, 2020
2BCW
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BU of 2bcw by Molmil
Coordinates of the N-terminal domain of ribosomal protein L11,C-terminal domain of ribosomal protein L7/L12 and a portion of the G' domain of elongation factor G, as fitted into cryo-em map of an Escherichia coli 70S*EF-G*GDP*fusidic acid complex
分子名称: 50S ribosomal protein L11, 50S ribosomal protein L7/L12, Elongation factor G
著者Datta, P.P, Sharma, M.R, Qi, L, Frank, J, Agrawal, R.K.
登録日2005-10-19
公開日2005-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (11.2 Å)
主引用文献Interaction of the G' Domain of Elongation Factor G and the C-Terminal Domain of Ribosomal Protein L7/L12 during Translocation as Revealed by Cryo-EM.
Mol.Cell, 20, 2005
2BM0
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BU of 2bm0 by Molmil
Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant T84A
分子名称: ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T.
登録日2005-03-09
公開日2005-05-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Insights Into Fusidic Acid Resistance and Sensitivity in EF-G
J.Mol.Biol., 348, 2005
2BM1
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BU of 2bm1 by Molmil
Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant G16V
分子名称: ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T.
登録日2005-03-09
公開日2005-05-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insights Into Fusidic Acid Resistance and Sensitivity in EF-G
J.Mol.Biol., 348, 2005
2BV3
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BU of 2bv3 by Molmil
Crystal structure of a mutant elongation factor G trapped with a GTP analogue
分子名称: ELONGATION FACTOR G, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T.
登録日2005-06-22
公開日2005-08-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of a Mutant Elongation Factor G Trapped with a GTP Analogue.
FEBS Lett., 579, 2005
3WIK
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BU of 3wik by Molmil
Crystal structure of the CK2alpha/compound10 complex
分子名称: Casein kinase II subunit alpha, N-[5-(4-nitrophenyl)-1,3,4-thiadiazol-2-yl]acetamide
著者Kinoshita, T, Nakaniwa, T, Sekiguchi, Y, Nakanishi, I.
登録日2013-09-18
公開日2014-11-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.995 Å)
主引用文献Identification of protein kinase CK2 inhibitors using solvent dipole ordering virtual screening
To be Published

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件を2024-07-24に公開中

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