3U6I
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8HL8
| Crystal structrue of MtdL R257K mutant | 分子名称: | MANGANESE (II) ION, Transglycosylse | 著者 | Li, F.D, He, C. | 登録日 | 2022-11-29 | 公開日 | 2023-03-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding. J.Biol.Chem., 299, 2023
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7X7E
| SARS-CoV-2 RBD and Nb22 | 分子名称: | Nb22, Spike protein S1, TETRAETHYLENE GLYCOL | 著者 | Wang, Y, Ye, S. | 登録日 | 2022-03-09 | 公開日 | 2022-04-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22). Front Immunol, 13, 2022
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7X7D
| SARS-CoV-2 Delta RBD and Nb22 | 分子名称: | Nb22, Spike protein S1 | 著者 | Wang, Y, Ye, S. | 登録日 | 2022-03-09 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22). Front Immunol, 13, 2022
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3PE6
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8PVM
| formaldehyde-inhibited [FeFe]-hydrogenase CpI from Clostridium pasteurianum, variant C299D | 分子名称: | CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, FORMYL GROUP, ... | 著者 | Duan, J, Hofmann, E, Happe, T. | 登録日 | 2023-07-18 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Insights into the Molecular Mechanism of Formaldehyde Inhibition of [FeFe]-Hydrogenases. J.Am.Chem.Soc., 145, 2023
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3NEF
| High-resolution pyrabactin-bound PYL1 structure | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL1 | 著者 | Yan, N. | 登録日 | 2010-06-08 | 公開日 | 2010-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Functional mechanism of the ABA agonist pyrabactin J.Biol.Chem., 285, 2010
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3NEG
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3U6H
| Crystal structure of c-Met in complex with pyrazolone inhibitor 26 | 分子名称: | Hepatocyte growth factor receptor, N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide | 著者 | Bellon, S.F, Whittington, D.A, Long, A.L. | 登録日 | 2011-10-12 | 公開日 | 2012-02-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives. J.Med.Chem., 55, 2012
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3TJD
| co-crystal structure of Jak2 with thienopyridine 19 | 分子名称: | 4-amino-2-[4-(tert-butylsulfamoyl)phenyl]-N-methylthieno[3,2-c]pyridine-7-carboxamide, Tyrosine-protein kinase JAK2 | 著者 | Huang, X. | 登録日 | 2011-08-24 | 公開日 | 2011-11-30 | 最終更新日 | 2011-12-28 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Discovery of potent and highly selective thienopyridine janus kinase 2 inhibitors. J.Med.Chem., 54, 2011
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3V43
| Crystal structure of MOZ | 分子名称: | ACETATE ION, Histone H3.1, Histone acetyltransferase KAT6A, ... | 著者 | Qiu, Y, Li, F. | 登録日 | 2011-12-14 | 公開日 | 2012-06-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription Genes Dev., 26, 2012
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8QM3
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7BZ5
| Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of B38, Light chain of B38, ... | 著者 | Wu, Y, Qi, J, Gao, F. | 登録日 | 2020-04-26 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2. Science, 368, 2020
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2HHJ
| Human bisphosphoglycerate mutase complexed with 2,3-bisphosphoglycerate (15 days) | 分子名称: | (2R)-2,3-diphosphoglyceric acid, 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, ... | 著者 | Wang, Y, Gong, W. | 登録日 | 2006-06-28 | 公開日 | 2006-10-24 | 最終更新日 | 2016-07-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase. J.Biol.Chem., 281, 2006
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2I6K
| Crystal structure of human type I IPP isomerase complexed with a substrate analog | 分子名称: | ACETIC ACID, AMINOETHANOLPYROPHOSPHATE, Isopentenyl-diphosphate delta-isomerase 1, ... | 著者 | Zhang, C, Wei, Z, Gong, W. | 登録日 | 2006-08-29 | 公開日 | 2007-06-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of human IPP isomerase: new insights into the catalytic mechanism J.Mol.Biol., 366, 2007
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6JUF
| SspB crystal structure | 分子名称: | SspB protein | 著者 | Liqiong, L, Yubing, Z. | 登録日 | 2019-04-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.587 Å) | 主引用文献 | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nat Microbiol, 5, 2020
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9B21
| Crystal structure of ADP-ribose diphosphatase from Klebsiella pneumoniae (ADP Ribose bound, Orthorhombic P form) | 分子名称: | ADP-ribose pyrophosphatase, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | 著者 | Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2024-03-14 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of ADP-ribose diphosphatase from Klebsiella pneumoniae (ADP Ribose bound, Orthorhombic P form) To be published
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6KVA
| Structure of anti-hCXCR2 abN48-2 in complex with its CXCR2 epitope | 分子名称: | 1,2-ETHANEDIOL, Peptide from C-X-C chemokine receptor type 2, heavy chain, ... | 著者 | Xiang, J.C, Yan, L, Yang, B, Wilson, I.A. | 登録日 | 2019-09-03 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms. Nat Commun, 12, 2021
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8IPR
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8IPQ
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6KVF
| Structure of anti-hCXCR2 abN48 in complex with its CXCR2 epitope | 分子名称: | Peptide from C-X-C chemokine receptor type 2, heavy chain, light chain | 著者 | Xiang, J.C, Yan, L, Yang, B, Wilson, I.A. | 登録日 | 2019-09-04 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms. Nat Commun, 12, 2021
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6LB9
| Magnesium ion-bound SspB crystal structure | 分子名称: | DUF4007 domain-containing protein, MAGNESIUM ION | 著者 | Liqiong, L, Yubing, Z. | 登録日 | 2019-11-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.227 Å) | 主引用文献 | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nat Microbiol, 5, 2020
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4I80
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8IPT
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8IPS
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