6PT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pt9 by Molmil](/molmil-images/mine/6pt9) | Crystal structure of PsS1_NC C84S in complex with k-neocarrabiose | 分子名称: | 1,2-ETHANEDIOL, 3,6-anhydro-D-galactose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Hettle, A.G, Boraston, A.B. | 登録日 | 2019-07-15 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
|
|
6PT4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pt4 by Molmil](/molmil-images/mine/6pt4) | Crystal structure of apo PsS1_NC | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Hettle, A.G, Boraston, A.B. | 登録日 | 2019-07-14 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
|
|
6OGI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ogi by Molmil](/molmil-images/mine/6ogi) | 70S termination complex with RF2 bound to the UAG codon. Rotated ribosome conformation (Structure V) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | 登録日 | 2019-04-02 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
|
|
6PZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pzz by Molmil](/molmil-images/mine/6pzz) | CryoEM derived model of NA-80 Fab in complex with N9 Shanghai2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NA-80 fragment antibody heavy chain, ... | 著者 | Ward, A.B, Turner, H.L, Zhu, X. | 登録日 | 2019-08-01 | 公開日 | 2019-12-04 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe, 26, 2019
|
|
6Q1P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6q1p by Molmil](/molmil-images/mine/6q1p) | Glucocerebrosidase in complex with pharmacological chaperone norIMX8 | 分子名称: | (2S,3S,4S,5R)-2-{[(4-methylpentyl)sulfonyl]methyl}piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Vickers, C, Withers, S.G, Boraston, A.B. | 登録日 | 2019-08-05 | 公開日 | 2020-08-19 | 実験手法 | X-RAY DIFFRACTION (2.796 Å) | 主引用文献 | Pharmacological chaperones for GCase that switch conformation with pH enhance enzyme levels in Gaucher animal models. To Be Published
|
|
6OGG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ogg by Molmil](/molmil-images/mine/6ogg) | 70S termination complex with RF2 bound to the UGA codon. Rotated ribosome with RF2 bound (Structure IV). | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | 登録日 | 2019-04-02 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
|
|
6ORH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6orh by Molmil](/molmil-images/mine/6orh) | Crystal structure of SpGH29 | 分子名称: | 1,2-ETHANEDIOL, Glycoside hydrolase, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose | 著者 | Pluvinage, B, Boraston, A.B. | 登録日 | 2019-04-30 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens. J.Biol.Chem., 294, 2019
|
|
6OGF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ogf by Molmil](/molmil-images/mine/6ogf) | 70S termination complex with RF2 bound to the UGA codon. Partially rotated ribosome with RF2 bound (Structure III). | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | 登録日 | 2019-04-02 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
|
|
6PV4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pv4 by Molmil](/molmil-images/mine/6pv4) | Structure of CpGH84A | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Glycoside Hydrolase | 著者 | Pluvinage, B, Boraston, A.B. | 登録日 | 2019-07-19 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional analysis of four family 84 glycoside hydrolases from the opportunistic pathogen Clostridium perfringens. Glycobiology, 30, 2019
|
|
6PTM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ptm by Molmil](/molmil-images/mine/6ptm) | |
6PZY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pzy by Molmil](/molmil-images/mine/6pzy) | CryoEM derived model of NA-73 Fab in complex with N9 Shanghai2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NA-73 fragment antibody heavy chain, ... | 著者 | Ward, A.B, Turner, H.L, Zhu, X. | 登録日 | 2019-08-01 | 公開日 | 2019-12-04 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe, 26, 2019
|
|
6Q1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6q1n by Molmil](/molmil-images/mine/6q1n) | Glucocerebrosidase in complex with pharmacological chaperone IMX8 | 分子名称: | (2R,3S,4S,5R)-2-[2-(methylsulfanyl)ethyl]piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Vickers, C, Withers, S.G, Boraston, A.B. | 登録日 | 2019-08-05 | 公開日 | 2020-08-19 | 実験手法 | X-RAY DIFFRACTION (2.526 Å) | 主引用文献 | Pharmacological chaperones for GCase that switch conformation with pH enhance enzyme levels in Gaucher animal models. To Be Published
|
|
6PZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pz8 by Molmil](/molmil-images/mine/6pz8) | MERS S0 trimer in complex with variable domain of antibody G2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G2 heavy chain, ... | 著者 | Bowman, C.A, Pallesen, J, Ward, A.B. | 登録日 | 2019-07-31 | 公開日 | 2019-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | 主引用文献 | Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD. Cell Rep, 28, 2019
|
|
6OG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6og7 by Molmil](/molmil-images/mine/6og7) | 70S termination complex with RF2 bound to the UGA codon. Non-rotated ribosome with RF2 bound (Structure II) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | 登録日 | 2019-04-01 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
|
|
6ORF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6orf by Molmil](/molmil-images/mine/6orf) | Crystal structure of SpGH29 | 分子名称: | 1,2-ETHANEDIOL, SpGH29, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose | 著者 | Pluvinage, B, Boraston, A.B. | 登録日 | 2019-04-30 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens. J.Biol.Chem., 294, 2019
|
|
6OR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6or4 by Molmil](/molmil-images/mine/6or4) | Crystal structure of SpGH29 | 分子名称: | Glycoside hydrolase, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Pluvinage, B, Boraston, A.B. | 登録日 | 2019-04-29 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens. J.Biol.Chem., 294, 2019
|
|
6PSO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pso by Molmil](/molmil-images/mine/6pso) | Crystal structure of PsS1_19B C77S in complex with iota-neocarratetraose | 分子名称: | 3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose-(1-4)-3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Hettle, A.G, Boraston, A.B. | 登録日 | 2019-07-13 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies. Commun Biol, 2, 2019
|
|
6PT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pt6 by Molmil](/molmil-images/mine/6pt6) | |
6U54
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u54 by Molmil](/molmil-images/mine/6u54) | Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire C (ZC) Complexed with Zaire ebolavirus Nucleoprotein C-terminal Domain 634-739 | 分子名称: | Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire C (ZC), Nucleoprotein | 著者 | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | 登録日 | 2019-08-26 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
|
|
6U02
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u02 by Molmil](/molmil-images/mine/6u02) | CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab-63 Heavy Chain, Fab-63 Light Chain, ... | 著者 | Ward, A.B, Turner, H.L, Zhu, X. | 登録日 | 2019-08-13 | 公開日 | 2019-12-04 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe, 26, 2019
|
|
6U4T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u4t by Molmil](/molmil-images/mine/6u4t) | Carbonic anhydrase 9 in complex with SB4197 | 分子名称: | 4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION | 著者 | Murray, A.B, Lomelino, C.L, McKenna, R. | 登録日 | 2019-08-26 | 公開日 | 2020-01-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.356 Å) | 主引用文献 | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
|
|
6U6Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u6z by Molmil](/molmil-images/mine/6u6z) | |
6UGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ugq by Molmil](/molmil-images/mine/6ugq) | Human Carbonic Anhydrase IX-mimic complexed with SB4-206 | 分子名称: | 5-chloro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase IX-mimic, ZINC ION | 著者 | Murray, A.B, Lomelino, C.L, McKenna, R. | 登録日 | 2019-09-26 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.305 Å) | 主引用文献 | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
|
|
6UH0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uh0 by Molmil](/molmil-images/mine/6uh0) | Human Carbonic Anhydrase 2 in complex with SB4-202 | 分子名称: | 4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION | 著者 | Murray, A.B, Lomelino, C.L, McKenna, R. | 登録日 | 2019-09-26 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.306 Å) | 主引用文献 | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
|
|
6U50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u50 by Molmil](/molmil-images/mine/6u50) | Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | 著者 | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | 登録日 | 2019-08-26 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
|
|