7V5J
| MERS S ectodomain trimer in complex with neutralizing antibody 0722(state 2) | 分子名称: | 0722 H, 0722 L, Spike glycoprotein | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | 登録日 | 2021-08-17 | 公開日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 0722(state 2) to be published
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7V6N
| MERS S ectodomain trimer in complex with neutralizing antibody 111 state1 | 分子名称: | 111 H, 111 L, Spike glycoprotein | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | 登録日 | 2021-08-20 | 公開日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 111 state1 to be published
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7V6O
| MERS S ectodomain trimer in complex with neutralizing antibody 111 (state 2) | 分子名称: | 111 H, 111 L, Spike glycoprotein | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | 登録日 | 2021-08-20 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (4.56 Å) | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 111 (state 2) to be published
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7XMK
| Crystal structure of human RIPK1 kinase domain in complex with compound SKLB923 | 分子名称: | 5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 | 著者 | Zhang, L, Wang, Y, Li, Y, Yang, S. | 登録日 | 2022-04-26 | 公開日 | 2023-04-26 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.376 Å) | 主引用文献 | From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases. J.Med.Chem., 67, 2024
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7XZ4
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7VI6
| Crystal structure of GH3 beta-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila | 分子名称: | Beta-N-acetylhexosaminidase, CHLORIDE ION, MAGNESIUM ION | 著者 | Qian, K, Yang, W, Chen, X, Wang, Y, Zhang, M, Wang, M. | 登録日 | 2021-09-26 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and structural characterization of a GH3 beta-N-acetylhexosaminidase from Akkermansia muciniphila involved in mucin degradation Biochem.Biophys.Res.Commun., 589, 2022
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7VI7
| Crystal structure of GH3 beta-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila in complex with GlcNAc | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ... | 著者 | Qian, K, Yang, W, Chen, X, Wang, Y, Zhang, M, Wang, M. | 登録日 | 2021-09-26 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and structural characterization of a GH3 beta-N-acetylhexosaminidase from Akkermansia muciniphila involved in mucin degradation Biochem.Biophys.Res.Commun., 589, 2022
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7VOO
| Induced alpha-2-macroglobulin monomer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | 著者 | Huang, X, Wang, Y, Ping, Z. | 登録日 | 2021-10-14 | 公開日 | 2022-10-19 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor. Sci China Life Sci, 65, 2022
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7X63
| SARS-CoV-2-Beta-RBD and BD-236-GWP/P-VK antibody complex | 分子名称: | BD-236 Fab heavy chain, BD-236 Fab light chain, Spike protein S1 | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | 登録日 | 2022-03-06 | 公開日 | 2023-03-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | SARS-CoV-2-Beta-RBD and BD-236-GWP/P-VK antibody complex To Be Published
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7XIK
| SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex | 分子名称: | B38 Fab heavy chain, B38 Fab light chain, Spike protein S1 | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | 登録日 | 2022-04-13 | 公開日 | 2023-04-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex To Be Published
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7XIL
| SARS-CoV-2-Beta-RBD and B38-GWP/P-VK antibody complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B38 Fab heavy chain, B38 Fab light chain, ... | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | 登録日 | 2022-04-13 | 公開日 | 2023-04-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | SARS-CoV-2-Beta-RBD and B38-GWP/P-VK antibody complex To Be Published
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7X66
| SARS-CoV-2-Omicron-RBD and BD-236-GWP/P-VK antibody complex | 分子名称: | BD-236 Fab heavy chain, BD-236 Fab light chain, Spike protein S1 | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | 登録日 | 2022-03-06 | 公開日 | 2023-03-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | SARS-CoV-2-Omicron-RBD and BD-236-GWP/P-VK antibody complex To Be Published
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7X4Y
| Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP-GABA complex | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Liu, S, Du, G, Wang, Y, Wen, B, Xin, F. | 登録日 | 2022-03-03 | 公開日 | 2023-04-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH. Food Chem, 403, 2023
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7X52
| Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP complex | 分子名称: | ACETATE ION, Glutamate decarboxylase, MALONATE ION, ... | 著者 | Liu, S, Du, G, Wang, Y, Wen, B, Xin, F. | 登録日 | 2022-03-03 | 公開日 | 2023-04-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH. Food Chem, 403, 2023
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7YL0
| Structure of hIAPP-TF-type2 | 分子名称: | Islet amyloid polypeptide | 著者 | Li, D, Zhang, X, Wang, Y, Zhu, P. | 登録日 | 2022-07-25 | 公開日 | 2022-12-28 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core. Iscience, 25, 2022
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7YKW
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7VON
| Native alpha-2-macroglobulin monomer | 分子名称: | Alpha-2-macroglobulin | 著者 | Huang, X, Wang, Y. | 登録日 | 2021-10-14 | 公開日 | 2022-11-16 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor. Sci China Life Sci, 65, 2022
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6OVB
| Crystal structure of a Bacillus thuringiensis Cry1Da tryptic core variant | 分子名称: | Active core crystal toxin protein 1D | 著者 | Rydel, T.J, Halls, C, Evdokimov, A.G, Beishir, S.C. | 登録日 | 2019-05-07 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.611 Å) | 主引用文献 | Bacillus thuringiensis Cry1Da_7 and Cry1B.868 Protein Interactions with Novel Receptors Allow Control of Resistant Fall Armyworms, Spodoptera frugiperda (J.E. Smith). Appl.Environ.Microbiol., 85, 2019
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7YMK
| Estrogen Receptor Alpha Ligand Binding Domain C381S C417S Y537S Mutant in Complex with an Covalent Selective Estrogen Receptor Degrader 29c and GRIP Peptide | 分子名称: | DI(HYDROXYETHYL)ETHER, Estrogen receptor, Grip peptide, ... | 著者 | Min, J, Hu, H.B, Yang, Y, Dong, C.E, Zhou, H.B, Chen, C.-C, Guo, R.-T. | 登録日 | 2022-07-28 | 公開日 | 2023-05-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Discovery of novel covalent selective estrogen receptor degraders against endocrine-resistant breast cancer. Acta Pharm Sin B, 13, 2023
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9IJB
| Crystal structure and function analysis of a highly potential drug target 6-phosphogluconate dehydrogenase in Mycobacterium tuberculosis | 分子名称: | 6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating | 著者 | Wang, Y.Z, Ren, X.Q, Li, T, Zhang, R.D. | 登録日 | 2024-06-22 | 公開日 | 2024-07-03 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.740405 Å) | 主引用文献 | Crystal structure and function analysis of 6-phosphogluconate dehydrogenase in Mycobacterium tuberculosis. Biochem.Biophys.Res.Commun., 731, 2024
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3RYT
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8GUN
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8GUP
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8GUO
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4O9S
| Crystal structure of Retinol-Binding Protein 4 (RBP4)in complex with a non-retinoid ligand | 分子名称: | 1,2-ETHANEDIOL, 1-[4-(7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),2(6),8,10-tetraen-12-yl)piperazin-1-yl]-2-[2-(trifluoromethyl)phenyl]ethanone, CHLORIDE ION, ... | 著者 | Wang, Z, Johnstone, S, Walker, N.P. | 登録日 | 2014-01-02 | 公開日 | 2014-07-02 | 最終更新日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4. Bioorg.Med.Chem.Lett., 24, 2014
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