8KGF
 
 | | Structure of AmCas12a with crRNA | | 分子名称: | CRISPR-associated endonuclease Cas12a, MAGNESIUM ION, RNA (44-MER) | | 著者 | Feng, Y, Zhang, X, Shi, J, Ma, P, Tang, J, Huang, X. | | 登録日 | 2023-08-18 | | 公開日 | 2024-09-04 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | A novel CRISPR/Cas12a in complex with a crRNA.
To Be Published
|
|
4PEK
 | | Crystal structure of a computationally designed retro-aldolase, RA114.3 | | 分子名称: | Retro-aldolase | | 著者 | Bhabha, G, Zhang, X, Liu, Y, Ekiert, D.C. | | 登録日 | 2014-04-23 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
|
|
1D59
 | | CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA | | 分子名称: | DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3') | | 著者 | Kang, C, Zhang, X, Ratliff, R, Moyzis, R, Rich, A. | | 登録日 | 1992-02-25 | | 公開日 | 1993-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of four-stranded Oxytricha telomeric DNA.
Nature, 356, 1992
|
|
4PEJ
 | | Crystal structure of a computationally designed retro-aldolase, RA110.4 (Cys free) | | 分子名称: | Retro-aldolase | | 著者 | Bhabha, G, Zhang, X, Liu, Y, Ekiert, D.C. | | 登録日 | 2014-04-23 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
|
|
8K59
 | | The cryo-EM map of TIC-TIEA complex | | 分子名称: | 15 kDa RNA polymerase-binding protein, DNA (61-MER), DNA (63-MER), ... | | 著者 | Zhang, K.N, Liu, Y, Chen, M, Wang, Y, Lin, W, Li, M, Zhang, X, Gao, Y, Gong, Q, Chen, H, Steve, M, Li, S, Zhang, K, Liu, B. | | 登録日 | 2023-07-21 | | 公開日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | TIEA inhibits sigma70-dependent transcriptions, accelerates elongation speed and elevates transcription error
To Be Published
|
|
1F9W
 | | CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION | | 著者 | Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. | | 登録日 | 2000-07-11 | | 公開日 | 2001-06-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A structural pathway for activation of the kinesin motor ATPase.
EMBO J., 20, 2001
|
|
1F9T
 | | CRYSTAL STRUCTURES OF KINESIN MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE MOTOR ATPASE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION | | 著者 | Yun, M, Zhang, X, Park, C.-G, Park, H.-W, Endow, S.A. | | 登録日 | 2000-07-11 | | 公開日 | 2001-06-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A structural pathway for activation of the kinesin motor ATPase.
EMBO J., 20, 2001
|
|
2H3B
 | | Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony Enhancing Factor 1 | | 分子名称: | Nicotinamide phosphoribosyltransferase, SULFATE ION | | 著者 | Wang, T, Zhang, X, Bheda, P, Revollo, J.R, Imai, S.I, Wolberger, C. | | 登録日 | 2006-05-22 | | 公開日 | 2006-06-20 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme.
Nat.Struct.Mol.Biol., 13, 2006
|
|
7E1H
 | | crystal structure of RD-BEF | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, DNA-binding response regulator, MAGNESIUM ION | | 著者 | Hong, S, Zhang, X, Zhang, P. | | 登録日 | 2021-02-01 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Structural basis of phosphorylation-induced activation of the response regulator VbrR.
Acta Biochim.Biophys.Sin., 2023
|
|
7E1B
 | | Crystal structure of VbrR-DNA complex | | 分子名称: | DNA (26-MER), DNA-binding response regulator | | 著者 | Hong, S, Zhang, X, Zhang, P. | | 登録日 | 2021-02-01 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (4.587 Å) | | 主引用文献 | Structural basis of phosphorylation-induced activation of the response regulator VbrR.
Acta Biochim.Biophys.Sin., 2023
|
|
2GZY
 | |
2GIC
 | | Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex | | 分子名称: | 45-MER, Nucleocapsid protein, URANYL (VI) ION | | 著者 | Green, T.J, Zhang, X, Wertz, G.W, Luo, M. | | 登録日 | 2006-03-28 | | 公開日 | 2006-08-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Structure of the vesicular stomatitis virus nucleoprotein-RNA complex unveils how the RNA is sequestered
Science, 313, 2006
|
|
2GZZ
 | |
4AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'GREEN' SUBSTATE, AVERAGE STRUCTURE | | 分子名称: | PHENOL, PROTEIN (INSULIN) | | 著者 | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | | 登録日 | 1998-12-29 | | 公開日 | 2000-02-28 | | 最終更新日 | 2024-11-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
|
|
1FZX
 | | NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAAAAACGG | | 分子名称: | 5'-D(*CP*CP*GP*TP*TP*TP*TP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*AP*AP*AP*AP*CP*GP*G)-3' | | 著者 | MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P. | | 登録日 | 2000-10-04 | | 公開日 | 2001-03-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of an A-tract DNA bend.
J.Mol.Biol., 306, 2001
|
|
2H3D
 | | Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony Enhancing Factor in Complex with Nicotinamide Mononuleotide | | 分子名称: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide phosphoribosyltransferase | | 著者 | Wang, T, Zhang, X, Bheda, P, Revollo, J.R, Imai, S.I, Wolberger, C. | | 登録日 | 2006-05-22 | | 公開日 | 2006-06-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme.
Nat.Struct.Mol.Biol., 13, 2006
|
|
2B37
 | | Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by 5-octyl-2-phenoxyphenol | | 分子名称: | 5-OCTYL-2-PHENOXYPHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | | 登録日 | 2005-09-19 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis
ACS Chem.Biol., 1, 2006
|
|
1G14
 | | NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAGAAACGG | | 分子名称: | 5'-D(*CP*CP*GP*TP*TP*TP*CP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*GP*AP*AP*AP*CP*GP*G)-3' | | 著者 | MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P. | | 登録日 | 2000-10-10 | | 公開日 | 2001-03-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of an A-tract DNA bend.
J.Mol.Biol., 306, 2001
|
|
1LFC
 | | BOVINE LACTOFERRICIN (LFCINB), NMR, 20 STRUCTURES | | 分子名称: | LACTOFERRICIN | | 著者 | Hwang, P.M, Zhou, N, Shan, X, Arrowsmith, C.H, Vogel, H.J. | | 登録日 | 1998-06-24 | | 公開日 | 1998-11-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of lactoferricin B, an antimicrobial peptide derived from bovine lactoferrin.
Biochemistry, 37, 1998
|
|
8XBK
 | | Crystal Structure of Human Liver Fructose-1,6-bisphosphatase Complexed with a Covalent Inhibitor | | 分子名称: | 1,2-ETHANEDIOL, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ... | | 著者 | Cao, H, Zhang, X, Ren, Y, Wan, J. | | 登録日 | 2023-12-06 | | 公開日 | 2024-11-20 | | 最終更新日 | 2024-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structure-Guided Design of Affinity/Covalent-Bond Dual-Driven Inhibitors Targeting the AMP Site of FBPase.
J.Med.Chem., 67, 2024
|
|
7LLY
 | | Oxyntomodulin-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein | | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wootten, D, Sexton, P.M, Belousoff, M.J, Danev, R, Zhang, X, Khoshouei, M, Venugopal, H. | | 登録日 | 2021-02-04 | | 公開日 | 2022-01-12 | | 最終更新日 | 2025-05-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
Nat Commun, 13, 2022
|
|
7LLL
 | | Exendin-4-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein | | 分子名称: | Exendin-4, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wootten, D, Sexton, P.M, Belousoff, M.J, Danev, R, Zhang, X, Khoshouei, M, Venugopal, H. | | 登録日 | 2021-02-04 | | 公開日 | 2022-01-12 | | 最終更新日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
Nat Commun, 13, 2022
|
|
8XOQ
 | | Human Calcium and Integrin Binding Protein 2 (CIB2) Fusion to TMC1 CBD-1 domain at 2.4 Angstroms resolution | | 分子名称: | MAGNESIUM ION, Transmembrane channel-like protein 1,Calcium and integrin-binding family member 2 | | 著者 | Li, Y.H, Chen, J.S, Zhang, X, Wang, C. | | 登録日 | 2024-01-02 | | 公開日 | 2025-01-15 | | 最終更新日 | 2025-03-12 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Structural insights into calcium-dependent CIB2-TMC1 interaction in hair cell mechanotransduction.
Commun Biol, 8, 2025
|
|
8V8K
 | | Crystal Structure of Nanobody NbE | | 分子名称: | Nanobody NbE | | 著者 | Koehl, A, Manglik, A, Yu, J, Kumar, A, Zhang, X, Martin, C, Raia, P, Steyaert, J, Ballet, S, Boland, A, Stoeber, M. | | 登録日 | 2023-12-05 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural basis of mu-opioid receptor targeting by a nanobody antagonist.
Nat Commun, 15, 2024
|
|
6A6B
 | | cryo-em structure of alpha-synuclein fiber | | 分子名称: | Alpha-synuclein | | 著者 | Li, Y.W, Zhao, C.Y, Luo, F, Liu, Z, Gui, X, Luo, Z, Zhang, X, Li, D, Liu, C, Li, X. | | 登録日 | 2018-06-27 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Amyloid fibril structure of alpha-synuclein determined by cryo-electron microscopy
Cell Res., 28, 2018
|
|
