8WM9
| Fzd4/DEP complex | 分子名称: | CHOLESTEROL HEMISUCCINATE, Frizzled-4, Segment polarity protein dishevelled homolog DVL-2 | 著者 | He, Y, Qian, Y. | 登録日 | 2023-10-03 | 公開日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Structural basis of Frizzled 4 in recognition of Dishevelled 2 unveils mechanism of WNT signaling activation. Nat Commun, 15, 2024
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8WMA
| Fzd4/DEP complex (local refined) | 分子名称: | Frizzled-4, Segment polarity protein dishevelled homolog DVL-2 | 著者 | He, Y, Qian, Y. | 登録日 | 2023-10-03 | 公開日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structural basis of Frizzled 4 in recognition of Dishevelled 2 unveils mechanism of WNT signaling activation. Nat Commun, 15, 2024
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7CRF
| Crystal structure of human TLR8 in complex with CU-CPD107 | 分子名称: | 1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-yl]-2-methyl-propan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... | 著者 | Sakaniwa, K, Tanji, H, Ohto, U, Shimizu, T. | 登録日 | 2020-08-13 | 公開日 | 2021-06-23 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists. Nat Commun, 12, 2021
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7CRZ
| Crystal structure of human glucose transporter GLUT3 bound with C3361 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Solute carrier family 2, ... | 著者 | Yuan, Y.Y, Zhang, S, Wang, N, Jiang, X, Yan, N. | 登録日 | 2020-08-14 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc.Natl.Acad.Sci.USA, 118, 2021
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7X08
| S protein of SARS-CoV-2 in complex with 2G1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | 著者 | Guo, Y.Y, Zhang, Y.Y, Zhou, Q. | 登録日 | 2022-02-21 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD. Cell Discov, 8, 2022
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7WZ7
| GPR110/G12 complex | 分子名称: | Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Zhu, X. | 登録日 | 2022-02-17 | 公開日 | 2022-09-28 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
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7WXU
| GPR110/Gq complex | 分子名称: | Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Zhu, X. | 登録日 | 2022-02-15 | 公開日 | 2022-09-28 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
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7WY0
| GPR110/G13 complex | 分子名称: | Adhesion G-protein coupled receptor F1, Engineered G alpha 13 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Zhu, X. | 登録日 | 2022-02-15 | 公開日 | 2022-09-28 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
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7WXW
| GPR110/Gs complex | 分子名称: | Adhesion G-protein coupled receptor F1, Engineered mini Galpha-s subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Zhu, X. | 登録日 | 2022-02-15 | 公開日 | 2022-09-28 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
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7X2V
| GPR110/Gi complex | 分子名称: | Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Zhu, X. | 登録日 | 2022-02-26 | 公開日 | 2022-09-28 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun, 13, 2022
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7X7R
| Cryo-EM structure of a bacterial protein | 分子名称: | RAMP superfamily protein, RNA (36-MER), RNA (5'-R(P*AP*GP*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*G)-3'), ... | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-10 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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7X8A
| Cryo-EM structure of a bacterial protein complex | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-11 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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7XC7
| Cryo-EM structure of a bacterial protein complex | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-23 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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7X7A
| Cryo-EM structure of SbCas7-11 in complex with crRNA and target RNA | 分子名称: | RAMP superfamily protein, RNA (33-MER), ZINC ION | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-09 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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7WQZ
| Structure of Active-mutEP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WR7
| Structure of Inhibited-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, Enteropeptidase catalytic light chain, ... | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WQW
| Structure of Active-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WQX
| Structure of Inactive-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WY5
| ADGRL3/Gq complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform 3 of Adhesion G protein-coupled receptor L3, ... | 著者 | He, Y, Qian, Y. | 登録日 | 2022-02-15 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling. Mol.Cell, 82, 2022
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7WY8
| ADGRL3/Gs complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform 3 of Adhesion G protein-coupled receptor L3, ... | 著者 | He, Y, Qian, Y. | 登録日 | 2022-02-15 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling Mol.Cell, 82, 2022
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7WYB
| ADGRL3/Gi complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | He, Y, Qian, Y. | 登録日 | 2022-02-15 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structural insights into adhesion GPCR ADGRL3 activation and G q , G s , G i , and G 12 coupling. Mol.Cell, 82, 2022
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7X10
| ADGRL3/miniG12 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform 3 of Adhesion G protein-coupled receptor L3, ... | 著者 | He, Y, Qian, Y. | 登録日 | 2022-02-22 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling. Mol.Cell, 82, 2022
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7YUB
| S1P-bound human SPNS2 | 分子名称: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, NbFab-H-chain, NbFab-L-chain, ... | 著者 | He, Y, Duan, Y. | 登録日 | 2022-08-17 | 公開日 | 2023-09-06 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
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6KF1
| Microbial Hormone-sensitive lipase- E53 mutant S162A | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HEXANOIC ACID, ... | 著者 | Xiaochen, Y, Zhengyang, L, Xuewei, X, Jixi, L. | 登録日 | 2019-07-05 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.996 Å) | 主引用文献 | Functional and Structural Insights into Environmental Adaptation of a Novel Hormone-sensitive Lipase, E53, Obtained from Erythrobacter longus To Be Published
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6KEU
| Wildtype E53, a microbial HSL esterase | 分子名称: | (4-nitrophenyl) hexanoate, 1,2-ETHANEDIOL, GLYCEROL, ... | 著者 | Yang, X.C, Li, Z.Y, Xu, X.W, Li, J.X. | 登録日 | 2019-07-05 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Wildtype E53, a microbial HSL esterase To Be Published
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