7X10

ADGRL3/miniG12 complex

Summary for 7X10

• Entry DOI: 10.2210/pdb7x10/pdb
• EMDB information: 32932
• Descriptor: engineered G alpha 12 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv16, ... (5 entities in total)
• Functional Keywords: gpcr, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 284055.71

Authors

He, Y.,Qian, Y. (deposition date: 2022-02-22, release date: 2022-11-09, Last modification date: 2022-11-30)

• Primary citation: Qian, Y.,Ma, Z.,Liu, C.,Li, X.,Zhu, X.,Wang, N.,Xu, Z.,Xia, R.,Liang, J.,Duan, Y.,Yin, H.,Xiong, Y.,Zhang, A.,Guo, C.,Chen, Z.,Huang, Z.,He, Y.; Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling.; Mol.Cell, 82:4340-4352.e6, 2022; PubMed: 36309016; DOI: 10.1016/j.molcel.2022.10.009

Experimental method

ELECTRON MICROSCOPY (2.93 Å)