2ON9
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2OLX
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2ONA
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2OL9
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2OMP
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2ONV
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2ONW
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1MQ7
| CRYSTAL STRUCTURE OF DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS (RV2697C) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE | 著者 | Sawaya, M.R, Chan, S, Segelke, B.W, Lekin, T, Heike, K, Cho, U.S, Naranjo, C, Perry, L.J, Yeates, T.O, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2002-09-13 | 公開日 | 2002-10-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. J.Mol.Biol., 341, 2004
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3CJB
| Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Sawaya, M.R, Kudryashov, D.S, Pashkov, I, Reisler, E, Yeates, T.O. | 登録日 | 2008-03-12 | 公開日 | 2008-03-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc.Natl.Acad.Sci.USA, 105, 2008
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3CJH
| Tim8-Tim13 complex | 分子名称: | Mitochondrial import inner membrane translocase subunit TIM13, Mitochondrial import inner membrane translocase subunit TIM8 | 著者 | Sawaya, M.R, Schmid, E, Beverly, K.N, Koehler, C.M. | 登録日 | 2008-03-12 | 公開日 | 2008-03-25 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Tim8-Tim13 complex has multiple substrate binding sites and binds cooperatively to Tim23 J.Mol.Biol., 382, 2008
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3CJC
| Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with DNase I and Gelsolin-segment 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Sawaya, M.R, Kudryashov, D.S, Pashkov, I, Reisler, E, Yeates, T.O. | 登録日 | 2008-03-12 | 公開日 | 2008-03-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc.Natl.Acad.Sci.USA, 105, 2008
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1DRH
| ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS | 分子名称: | DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Sawaya, M.R, Kraut, J. | 登録日 | 1994-11-30 | 公開日 | 1995-02-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry, 34, 1995
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3VCD
| Computationally Designed Self-assembling Octahedral Cage protein, O333, Crystallized in space group R32 | 分子名称: | CHLORIDE ION, Propanediol utilization polyhedral body protein PduT, SULFATE ION | 著者 | Sawaya, M.R, King, N.P, Sheffler, W, Baker, D, Yeates, T.O. | 登録日 | 2012-01-03 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science, 336, 2012
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3GGS
| Human purine nucleoside phosphorylase double mutant E201Q,N243D complexed with 2-fluoro-2'-deoxyadenosine | 分子名称: | 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL, Purine nucleoside phosphorylase, SULFATE ION | 著者 | Sawaya, M.R, Afshar, S. | 登録日 | 2009-03-02 | 公開日 | 2009-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. Protein Sci., 18, 2009
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3HLC
| Simvastatin Synthase (LovD) from Aspergillus terreus, S5 mutant, unliganded | 分子名称: | GLYCEROL, TETRAETHYLENE GLYCOL, Transesterase | 著者 | Sawaya, M.R, Yeates, T.O, Laidman, J, Pashkov, I, Gao, X, Tang, Y. | 登録日 | 2009-05-27 | 公開日 | 2009-10-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
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3HLD
| Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant complex with monacolin J acid | 分子名称: | (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, FORMIC ACID, Transesterase | 著者 | Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. | 登録日 | 2009-05-27 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
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3HLG
| Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with lovastatin | 分子名称: | (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID, Transesterase | 著者 | Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. | 登録日 | 2009-05-27 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
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3HLE
| Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with monacolin J acid | 分子名称: | (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Transesterase | 著者 | Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. | 登録日 | 2009-05-27 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
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3HLF
| Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with simvastatin | 分子名称: | Simvastatin acid, Transesterase | 著者 | Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. | 登録日 | 2009-05-27 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
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3HL9
| Simvastatin Synthase (LovD) from Aspergillus terreus, unliganded | 分子名称: | Transesterase | 著者 | Sawaya, M.R, Yeates, T.O, Laidman, J, Pashkov, I, Gao, X, Tang, Y. | 登録日 | 2009-05-27 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
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3HLB
| Simvastatin Synthase (LovD) from Aspergillus terreus, unliganded, selenomethionyl derivative | 分子名称: | SULFATE ION, Transesterase | 著者 | Sawaya, M.R, Yeates, T.O, Laidman, J, Pashkov, I, Gao, X, Tang, Y. | 登録日 | 2009-05-27 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
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3GB9
| Human purine nucleoside phosphorylase double mutant E201Q,N243D complexed with 2-fluoroadenine | 分子名称: | 2-fluoroadenine, GLYCEROL, Purine nucleoside phosphorylase, ... | 著者 | Sawaya, M.R, Afshar, S. | 登録日 | 2009-02-19 | 公開日 | 2009-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. Protein Sci., 18, 2009
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1F1C
| CRYSTAL STRUCTURE OF CYTOCHROME C549 | 分子名称: | CYTOCHROME C549, HEME C | 著者 | Kerfeld, C.A, Sawaya, M.R, Yeates, T.O, Krogmann, D.W. | 登録日 | 2000-05-18 | 公開日 | 2001-08-08 | 最終更新日 | 2021-03-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima. Biochemistry, 40, 2001
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1F1F
| CRYSTAL STRUCTURE OF CYTOCHROME C6 FROM ARTHROSPIRA MAXIMA | 分子名称: | CYTOCHROME C6, HEME C | 著者 | Kerfeld, C.A, Serag, A.A, Sawaya, M.R, Krogmann, D.W, Yeates, T.O. | 登録日 | 2000-05-18 | 公開日 | 2001-08-08 | 最終更新日 | 2021-03-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima. Biochemistry, 40, 2001
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3NI3
| 54-Membered ring macrocyclic beta-sheet peptide | 分子名称: | 54-membered ring macrocyclic beta-sheet peptide, ISOPROPYL ALCOHOL | 著者 | Sawaya, M.R, Eisenberg, D, Nowick, J.S, Korman, T.P, Khakshoor, O. | 登録日 | 2010-06-15 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | X-ray crystallographic structure of an artificial beta-sheet dimer. J.Am.Chem.Soc., 132, 2010
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