4D4E
 
 | | Crystal structure of computationally designed armadillo repeat proteins for modular peptide recognition. | | 分子名称: | ARMADILLO REPEAT PROTEIN ARM00016, GLYCEROL | | 著者 | Reichen, C, Forzani, C, Zhou, T, Parmeggiani, F, Fleishman, S.J, Mittl, P.R.E, Madhurantakam, C, Honegger, A, Ewald, C, Zerbe, O, Baker, D, Caflisch, A, Pluckthun, A. | | 登録日 | 2014-10-28 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
J.Mol.Biol., 428, 2016
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7TAL
 | | LOV2-DARPIN fusion : D4_deltaDARP | | 分子名称: | D4_deltaDARP LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION | | 著者 | Mittl, P. | | 登録日 | 2021-12-21 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | LOV2-DARPIN fusion : D4_deltaDARP
To Be Published
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7TBN
 | | LOV2-DARPIN fusion : D11 | | 分子名称: | CARBONATE ION, D11 LOV2-DARPin fusion, GLYCEROL | | 著者 | Mittl, P. | | 登録日 | 2021-12-22 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | LOV2-DARPIN fusion : D11
To Be Published
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7TBO
 | | LOV2-DARPIN fusion : D12 | | 分子名称: | D12 LOV2-DARPin fusion, GLYCEROL | | 著者 | Mittl, P. | | 登録日 | 2021-12-22 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | LOV2-DARPIN fusion : D12
To Be Published
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7TBQ
 | | LOV2-DARPIN fusion : D7 | | 分子名称: | CHLORIDE ION, D7 LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Mittl, P. | | 登録日 | 2021-12-22 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.678 Å) | | 主引用文献 | LOV2-DARPIN fusion : D7
To Be Published
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1HIA
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7QNL
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4V3Q
 | | Designed armadillo repeat protein with 4 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | | 分子名称: | CALCIUM ION, GLYCEROL, YIII_M4_AII | | 著者 | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | | 登録日 | 2014-10-20 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects.
Acta Crystallogr D Struct Biol, 72, 2016
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5AAO
 | | Crystal structure of fluorogen-activating designed ankyrin repeat protein (DARPin) dimer in complex with malachite green | | 分子名称: | 4-[[4-(dimethylamino)cyclohexa-2,5-dien-1-ylidene]-(4-methoxyphenyl)methyl]-N,N-dimethyl-aniline, FAD3210 | | 著者 | Batyuk, A, Schuetz, M, Kummer, L, Wu, Y, Mittl, P, Plueckthun, A. | | 登録日 | 2015-07-27 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools.
J. Mol. Biol., 428, 2016
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5AOU
 | | Structure of the engineered retro-aldolase RA95.5-8F apo | | 分子名称: | 1,2-ETHANEDIOL, INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE, PHOSPHATE ION | | 著者 | Obexer, R, Mittl, P, Hilvert, D. | | 登録日 | 2015-09-11 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase.
Nat Chem, 9, 2017
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4PLR
 | | Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure. | | 分子名称: | Arm00008, CALCIUM ION | | 著者 | Reichen, C, Madhurantakam, C, Plueckthun, A, Mittl, P. | | 登録日 | 2014-05-19 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of designed armadillo repeat proteins: Implications of construct design and crystallization conditions on overall structure.
Protein Sci., 23, 2014
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3N5I
 | | Crystal structure of the precursor (S250A mutant) of the N-terminal beta-aminopeptidase BapA | | 分子名称: | Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION | | 著者 | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | | 登録日 | 2010-05-25 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012
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3N2W
 | | Crystal structure of the N-terminal beta-aminopeptidase BapA from Sphingosinicella xenopeptidilytica | | 分子名称: | Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION | | 著者 | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | | 登録日 | 2010-05-19 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012
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3N33
 | | Crystal structure of the N-terminal beta-aminopeptidase BapA in complex with pefabloc SC (AEBSF) | | 分子名称: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-peptidyl aminopeptidase, ... | | 著者 | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | | 登録日 | 2010-05-19 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012
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5L86
 | | engineered ascorbate peroxidise | | 分子名称: | Ascorbate peroxidase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Hayashi, T, Mittl, P, Hilvert, D. | | 登録日 | 2016-06-07 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A Chemically Programmed Proximal Ligand Enhances the Catalytic Properties of a Heme Enzyme.
J. Am. Chem. Soc., 138, 2016
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1QDU
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6HV2
 | | MMP-13 in complex with the peptide IMISF | | 分子名称: | CALCIUM ION, Collagenase 3, GLYCEROL, ... | | 著者 | Mittl, P, Riedl, R, Hohl, D. | | 登録日 | 2018-10-10 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.709 Å) | | 主引用文献 | Drug Design Inspired by Nature: Crystallographic Detection of an Auto-Tailored Protease Inhibitor Template.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6YE3
 | | IL-2 in complex with a Fab fragment from UFKA-20 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chains: A,D,G, Chains: B,E,H, ... | | 著者 | Karakus, U, Mittl, P, Boyman, O. | | 登録日 | 2020-03-23 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species.
Sci Transl Med, 12, 2020
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6NW4
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4V3R
 | | Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | | 分子名称: | MAGNESIUM ION, YIII_M5_AII | | 著者 | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | | 登録日 | 2014-10-20 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects
Acta Crystallogr.,Sect.D, 72, 2016
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4V3O
 | | Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | | 分子名称: | ACETATE ION, CALCIUM ION, YIII_M5_AII | | 著者 | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | | 登録日 | 2014-10-20 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects
Acta Crystallogr.,Sect.D, 72, 2016
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8AGQ
 | | Crystal structure of anthocyanin-related GSTF8 from Populus trichocarpa in complex with (-)-catechin and glutathione | | 分子名称: | (2~{S},3~{R})-2-[3,4-bis(oxidanyl)phenyl]-3,4-dihydro-2~{H}-chromene-3,5,7-triol, GLUTATHIONE, Glutathione transferase, ... | | 著者 | Eichenberger, M, Hueppi, S, Schwander, T, Mittl, P, Buller, M.R. | | 登録日 | 2022-07-20 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.093 Å) | | 主引用文献 | The catalytic role of glutathione transferases in heterologous anthocyanin biosynthesis.
Nat Catal, 6, 2023
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8AED
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8AH9
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7YWJ
 | | Crystal structure of an engineered TycA variant, TycA pPLA (L313P) | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ... | | 著者 | Mittl, P, Camus, A, Truong, G, Markert, G, Hilvert, D. | | 登録日 | 2022-02-14 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of alpha-Hydroxy Acids.
J.Am.Chem.Soc., 144, 2022
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