8PI8
| DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA | 分子名称: | Chains: E, Chains: F, GLYCEROL, ... | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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8PI9
| DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>A) | 分子名称: | Chains: E, Chains: F, Hepatocyte nuclear factor 1-alpha | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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8PI7
| DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -169C>T) | 分子名称: | CHLORIDE ION, Chains: E, Chains: F, ... | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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6NRI
| Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT83 | 分子名称: | (2Z)-2-{[4-(3-cyclopropyl-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carbonyl)phenyl]methylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide, CHLORIDE ION, CITRIC ACID, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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6NRH
| Crystal Structure of human PARP-1 ART domain bound inhibitor UTT63 | 分子名称: | 3-hydroxy-2-({4-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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6NRJ
| Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT93 | 分子名称: | (2Z)-2-[(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)methylidene]-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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6NRG
| Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT57 | 分子名称: | 2-{[3-fluoro-4-(1H-tetrazol-5-yl)phenyl]methyl}-3-hydroxy-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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6NRF
| Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT103 | 分子名称: | 2-({4-[4-(1H-benzimidazol-2-yl)piperazine-1-carbonyl]phenyl}methyl)-3-hydroxy-1-benzofuran-7-carboxamide, CHLORIDE ION, CITRIC ACID, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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1HB7
| quasi-atomic resolution model of bacteriophage PRD1 sus1 mutant, obtained by combined cryo-EM and X-ray crystallography. | 分子名称: | BACTERIOPHAGE PRD1 SUS1 MUTANT CAPSID | 著者 | San Martin, C, Burnett, R.M, De Haas, F, Heinkel, R, Rutten, T, Fuller, S.D, Butcher, S.J, Bamford, D.H. | 登録日 | 2001-04-12 | 公開日 | 2001-12-05 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | Combined Em/X-Ray Imaging Yields a Quasi-Atomic Model of the Adenovirus-Related Bacteriophage Prd1 and Shows Key Capsid and Membrane Interactions. Structure, 9, 2001
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8CN1
| hDLG1-PDZ1 in complex with a TAX1 peptide from HTLV-1 | 分子名称: | Disks large homolog 1, GLU-THR-GLU-VAL, SULFATE ION | 著者 | Maseko, S, Sogues, A, Volkov, A, Remaut, H, Twizere, J.C. | 登録日 | 2023-02-21 | 公開日 | 2023-08-02 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction. Antiviral Res., 217, 2023
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8CN3
| hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1 | 分子名称: | Disks large homolog 1, GLU-THR-GLU-VAL | 著者 | Maseko, S, Sogues, A, Volkov, A, Remaut, H, Twizere, J.C. | 登録日 | 2023-02-21 | 公開日 | 2023-08-02 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction. Antiviral Res., 217, 2023
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7AHO
| RUVBL1-RUVBL2 heterohexameric ring after binding of RNA helicase DHX34 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | 著者 | Lopez-Perrote, A, Rodriguez, C.F, Llorca, O. | 登録日 | 2020-09-25 | 公開日 | 2020-11-25 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM. Elife, 9, 2020
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5JWK
| Factor Inhibiting HIF D201E in Complex with Fe, and Alpha-Ketoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | 著者 | Taabazuing, C.Y, Garman, S.C, Knapp, M.J, Eron, S. | 登録日 | 2016-05-12 | 公開日 | 2017-05-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Factor Inhibiting HIF D201E in Complex with Fe, and Alpha-Ketoglutarate To Be Published
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5JWL
| Factor Inhibiting HIF D201E in Complex with Zn, and Alpha-Ketoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, Hypoxia-inducible factor 1-alpha inhibitor, ... | 著者 | Taabazuing, C.Y, Garman, S.C, Eron, S, Knapp, M.J. | 登録日 | 2016-05-12 | 公開日 | 2017-05-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Factor Inhibiting HIF D201E in Complex with Zn, and Alpha-Ketoglutarate To Be Published
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5G5N
| Structure of the snake adenovirus 1 hexon-interlacing LH3 protein, methylmercury chloride derivative | 分子名称: | CHLORIDE ION, GLYCEROL, LH3 HEXON-INTERLACING CAPSID PROTEIN, ... | 著者 | Nguyen, T.H, Singh, A.K, Albala-Perez, B, van Raaij, M.J. | 登録日 | 2016-05-26 | 公開日 | 2017-06-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of a Reptilian Adenovirus Reveals a Phage Tailspike Fold Stabilizing a Vertebrate Virus Capsid. Structure, 25, 2017
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5G5O
| Structure of the snake adenovirus 1 hexon-interlacing LH3 protein, native | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Nguyen, T.H, Singh, A.K, Albala-Perez, B, van Raaij, M.J. | 登録日 | 2016-05-26 | 公開日 | 2017-06-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a Reptilian Adenovirus Reveals a Phage Tailspike Fold Stabilizing a Vertebrate Virus Capsid. Structure, 25, 2017
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6GY2
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4D1G
| Crystal structure of the fiber head domain of the Atadenovirus snake adenovirus 1, native, second P212121 crystal form | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, FIBER PROTEIN, SULFATE ION | 著者 | Singh, A.K, van Raaij, M.J. | 登録日 | 2014-05-01 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the fibre head domain of the Atadenovirus Snake Adenovirus 1. PLoS ONE, 9, 2014
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4D1F
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4D0U
| Crystal structure of the fiber head domain of the Atadenovirus snake adenovirus 1, selenomethionine-derivative | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, FIBER PROTEIN, SULFATE ION | 著者 | Singh, A.K, van Raaij, M.J. | 登録日 | 2014-04-30 | 公開日 | 2014-12-17 | 最終更新日 | 2018-12-19 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the fibre head domain of the Atadenovirus Snake Adenovirus 1. PLoS ONE, 9, 2014
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4D0V
| Crystal structure of the fiber head domain of the Atadenovirus snake adenovirus 1, native, I213 crystal form | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, FIBER PROTEIN, SULFATE ION | 著者 | Singh, A.K, van Raaij, M.J. | 登録日 | 2014-04-30 | 公開日 | 2014-12-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of the fibre head domain of the Atadenovirus Snake Adenovirus 1. PLoS ONE, 9, 2014
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8BFR
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8BFT
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4E52
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4EKF
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