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4ALZ
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BU of 4alz by Molmil
The Yersinia T3SS basal body component YscD reveals a different structural periplasmatic domain organization to known homologue PrgH
分子名称: GLYCEROL, PHOSPHATE ION, YOP PROTEINS TRANSLOCATION PROTEIN D
著者Schmelz, S, Wisand, U, Stenta, M, Muenich, S, Widow, U, Cornelis, G.R, Heinz, D.W.
登録日2012-03-06
公開日2013-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献In Situ Structural Analysis of the Yersinia Enterocolitica Injectisome.
Elife, 2, 2013
6QEE
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BU of 6qee by Molmil
Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ABCB1HM-EQ, ...
著者Alam, A.
登録日2019-01-07
公開日2019-02-27
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.
Science, 363, 2019
7A65
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BU of 7a65 by Molmil
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E
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BU of 7a6e by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A69
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BU of 7a69 by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-21
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F
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BU of 7a6f by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6C
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BU of 7a6c by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
分子名称: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
5NIV
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BU of 5niv by Molmil
Crystal structure of 5D3 Fab
分子名称: Heavy chain of 5D3 Fab, Light chain of 5D3 Fab
著者Manolaridis, I, Locher, K.P.
登録日2017-03-27
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Structure of the human multidrug transporter ABCG2.
Nature, 546, 2017
6STS
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BU of 6sts by Molmil
Human myelin protein P2 mutant R30Q
分子名称: Myelin P2 protein, PALMITIC ACID, SULFATE ION
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2019-09-11
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XVS
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BU of 6xvs by Molmil
Human myelin protein P2 mutant P38G, unliganded
分子名称: GLYCEROL, Myelin P2 protein
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-22
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XUW
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BU of 6xuw by Molmil
Human myelin protein P2 mutant L27D
分子名称: CHLORIDE ION, Myelin P2 protein, PALMITIC ACID
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-21
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XVQ
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BU of 6xvq by Molmil
Human myelin protein P2 mutant K31Q
分子名称: CITRIC ACID, Myelin P2 protein, PALMITIC ACID
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-22
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XVY
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BU of 6xvy by Molmil
Human myelin protein P2 mutant R88Q
分子名称: CHLORIDE ION, CITRIC ACID, Myelin P2 protein, ...
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-22
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XU5
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BU of 6xu5 by Molmil
Human myelin protein P2 mutant N2D
分子名称: CITRIC ACID, Myelin P2 protein, PALMITIC ACID
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-17
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XUA
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BU of 6xua by Molmil
Human myelin protein P2 mutant K21Q
分子名称: CITRIC ACID, Myelin P2 protein, PALMITIC ACID
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-17
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XW9
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BU of 6xw9 by Molmil
Human myelin protein P2 mutant K120S
分子名称: CHLORIDE ION, Myelin P2 protein, PALMITIC ACID
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-23
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XU9
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BU of 6xu9 by Molmil
Human myelin protein P2 mutant K3N
分子名称: CHLORIDE ION, CITRIC ACID, Myelin P2 protein, ...
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-17
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6XVR
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BU of 6xvr by Molmil
Human myelin protein P2 mutant L35S
分子名称: Myelin P2 protein, PALMITIC ACID, SULFATE ION
著者Ruskamo, S, Lehtimaki, M, Kursula, P.
登録日2020-01-22
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
6FN1
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BU of 6fn1 by Molmil
Zosuquidar and UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Human-mouse chimeric ABCB1 (ABCBHM), UIC2 Antigen Binding Fragment Heavy Chain, ...
著者Alam, A, Locher, K.P.
登録日2018-02-02
公開日2018-02-21
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FN4
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BU of 6fn4 by Molmil
Apo form of UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Apo form of Human-mouse chimeric ABCB1 (ABCB1HM) in complex with Antigen binding fragment of UIC2., ...
著者Alam, A, Locher, K.P.
登録日2018-02-02
公開日2018-02-21
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7T7H
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BU of 7t7h by Molmil
Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with inhibitor CP100356
分子名称: 4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-2-amine, DNA repair NTP-phosphohydrolase, SODIUM ION
著者Peters, J.K, Gross, J.D.
登録日2021-12-15
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.78000259 Å)
主引用文献Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9.
Acs Chem.Biol., 17, 2022
1CLS
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BU of 1cls by Molmil
CROSS-LINKED HUMAN HEMOGLOBIN DEOXY
分子名称: HEMOGLOBIN, OXYGEN ATOM, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ji, X, Fronticelli, C, Bucci, E, Gilliland, G.L.
登録日1995-08-29
公開日1996-10-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Positive and negative cooperativities at subsequent steps of oxygenation regulate the allosteric behavior of multistate sebacylhemoglobin.
Biochemistry, 35, 1996
6WUG
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BU of 6wug by Molmil
Crystal Structure of S. pombe Rai1 in complex with 3'-FADP
分子名称: 1,2-ETHANEDIOL, Decapping nuclease din1, MAGNESIUM ION, ...
著者Doamekpor, S.K, Tong, L.
登録日2020-05-04
公開日2020-05-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs.
Nucleic Acids Res., 48, 2020
6WUK
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BU of 6wuk by Molmil
Crystal structure of mouse DXO in complex with CoA
分子名称: COENZYME A, Decapping and exoribonuclease protein
著者Doamekpor, S.K, Tong, L.
登録日2020-05-04
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs.
Nucleic Acids Res., 48, 2020
2HHE
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BU of 2hhe by Molmil
OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA CHAINS IN HUMAN AND BOVINE HEMOGLOBIN
分子名称: HEMOGLOBIN (DEOXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
著者Gilliland, G.L, Pechik, I, Fronticelli, C, Ji, X.
登録日1994-09-29
公開日1995-01-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Chloride ion independence of the Bohr effect in a mutant human hemoglobin beta (V1M+H2deleted).
J.Biol.Chem., 269, 1994

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