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3ROJ
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D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase of Synechocystis sp. PCC 6803
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, ...
著者Hu, X, Hui, D, Lingling, F, Jian, W.
登録日2011-04-26
公開日2012-05-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献New insights into the structural and interactional basis for a promising route towards fructose-1,6-/sedoheptulose-1,7-bisphosphatases controlling
To be Published
4WUM
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X-ray crystal structure of Chalcone Synthase from Freesia hybrida
分子名称: Chalcone synthase
著者Almqvist, J, Jiang, W.S, Wang, L, Huang, Y.
登録日2014-11-02
公開日2014-11-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Molecular and Biochemical Analysis of Chalcone Synthase from Freesia hybrid in Flavonoid Biosynthetic Pathway.
Plos One, 10, 2015
8IV5
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Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4 (local refinement)
分子名称: Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, heavy chain of 1C4, ...
著者Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N.
登録日2023-03-26
公開日2023-08-16
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
8IV8
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Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 3E2 and 1C4 (local refinement)
分子名称: Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, heavy chain of 1C4, ...
著者Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N.
登録日2023-03-26
公開日2023-08-16
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
8IVA
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BU of 8iva by Molmil
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs XMA01 and 3E2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, heavy chain of 3E2, ...
著者Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N.
登録日2023-03-26
公開日2023-08-16
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
8IV4
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Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 3E2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, heavy chain of 3E2, ...
著者Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N.
登録日2023-03-26
公開日2023-08-16
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
4WJA
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BU of 4wja by Molmil
Crystal Structure of PAXX
分子名称: Uncharacterized protein C9orf142
著者Xing, M, Yang, M, Huo, W, Feng, F, Wei, L, Ning, S, Yan, Z, Li, W, Wang, Q, Hou, M, Dong, C, Guo, R, Gao, G, Ji, J, Lan, L, Liang, H, Xu, D.
登録日2014-09-29
公開日2015-03-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway.
Nat Commun, 6, 2015
1MJC
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BU of 1mjc by Molmil
CRYSTAL STRUCTURE OF CSPA, THE MAJOR COLD SHOCK PROTEIN OF ESCHERICHIA COLI
分子名称: MAJOR COLD-SHOCK PROTEIN 7.4
著者Schindelin, H, Heinemann, U.
登録日1994-03-18
公開日1994-06-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of CspA, the major cold shock protein of Escherichia coli.
Proc.Natl.Acad.Sci.USA, 91, 1994
3MEF
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BU of 3mef by Molmil
MAJOR COLD-SHOCK PROTEIN FROM ESCHERICHIA COLI SOLUTION NMR STRUCTURE
分子名称: PROTEIN (COLD-SHOCK PROTEIN A)
著者Feng, W, Tejero, R, Montelione, G.T.
登録日1998-10-09
公開日1998-10-14
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution NMR structure and backbone dynamics of the major cold-shock protein (CspA) from Escherichia coli: evidence for conformational dynamics in the single-stranded RNA-binding site.
Biochemistry, 37, 1998
7BP4
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BU of 7bp4 by Molmil
Structural insights into nucleosome reorganization by NAP1-RELATED PROTEIN 1 (NRP1)
分子名称: ASP-ASP-ASP-ASP-TYR, GLYCEROL, Histone H2A.6, ...
著者Luo, Q, Baihui, W.
登録日2020-03-21
公開日2020-11-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BP6
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Structural insights into nucleosome reorganization by NAP1-RELATED PROTEIN 1 (NRP1)
分子名称: Histone H2A.6, Histone H2B.1, NRP1-CTAD
著者Luo, Q, Baihui, W.
登録日2020-03-21
公開日2020-11-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BP2
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BU of 7bp2 by Molmil
Structural mechanism directing nucleosome reorganization by NAP1-RELATED PROTEIN 1 (NRP1)
分子名称: GLYCEROL, Histone H2A.6, Histone H2B.1, ...
著者Luo, Q, Baihui, W.
登録日2020-03-21
公開日2020-11-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BP5
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BU of 7bp5 by Molmil
Structural insights into nucleosome reorganization by NAP1-RELATED PROTEIN 1 (NRP1)
分子名称: ASN-ASP-PRO-ASP-TYR, GLYCEROL, Histone H2A.6, ...
著者Luo, Q, Baihui, W.
登録日2020-03-21
公開日2020-11-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 117, 2020
5ZBZ
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BU of 5zbz by Molmil
Crystal structure of the DEAD domain of Human eIF4A with sanguinarine
分子名称: 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, Eukaryotic initiation factor 4A-I, MALONATE ION
著者Ding, Y, Ding, L.
登録日2018-02-14
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.30860257 Å)
主引用文献Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling.
Cell Chem Biol, 26, 2019
7YGI
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BU of 7ygi by Molmil
Crystal structure of p53 DBD domain in complex with azurin
分子名称: Azurin, Cellular tumor antigen p53, PHOSPHATE ION, ...
著者Jiang, W.X, Zuo, J.Q, Hu, J.J, Chen, X.Q, Ma, L.X, Liu, Z, Xing, Q.
登録日2022-07-11
公開日2023-02-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
Commun Biol, 6, 2023
6EAZ
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BU of 6eaz by Molmil
Apo structure of the mitochondrial calcium uniporter protein MICU2
分子名称: Calcium uptake protein 2, mitochondrial, GLYCEROL
著者Kamer, K.J, Grabarek, Z.
登録日2018-08-03
公開日2019-02-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
9CZN
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BU of 9czn by Molmil
Type Ic amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques
分子名称: Amyloid-beta protein 42
著者Hoq, M.R, Vago, F.S, Ozcan, K.A, Bharath, S.R.
登録日2024-08-05
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
9CZL
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Straight tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques
分子名称: Isoform Tau-C of Microtubule-associated protein tau
著者Hoq, M.R, Vago, F.S, Ozcan, K.A, Bharath, S.R.
登録日2024-08-05
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
9CZI
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BU of 9czi by Molmil
Paired helical tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques
分子名称: Microtubule-associated protein tau
著者Hoq, M.R, Vago, F.S, Ozcan, K.A, Bharath, S.R.
登録日2024-08-05
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
9CZP
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Type Id amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques
分子名称: Amyloid-beta protein 42
著者Hoq, M.R, Vago, F.S, Ozcan, K.A, Bharath, S.R.
登録日2024-08-05
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
4O1I
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Crystal Structure of the regulatory domain of MtbGlnR
分子名称: Transcriptional regulatory protein
著者Lin, W, Wang, C, Zhang, P.
登録日2013-12-16
公開日2014-04-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Atypical OmpR/PhoB Subfamily Response Regulator GlnR of Actinomycetes Functions as a Homodimer, Stabilized by the Unphosphorylated Conserved Asp-focused Charge Interactions
J.Biol.Chem., 289, 2014
6J8L
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Phytophthora sojae effector PsAvh240 inhibits a host aspartic protease secretion to promote infection
分子名称: Avh240, SULFATE ION
著者Guo, B.
登録日2019-01-19
公開日2019-02-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Phytophthora sojae Effector PsAvh240 Inhibits Host Aspartic Protease Secretion to Promote Infection.
Mol Plant, 12, 2019
4O1H
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Crystal Structure of the regulatory domain of AmeGlnR
分子名称: Transcription regulator GlnR
著者Lin, W, Wang, C, Zhang, P.
登録日2013-12-16
公開日2014-04-23
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Atypical OmpR/PhoB Subfamily Response Regulator GlnR of Actinomycetes Functions as a Homodimer, Stabilized by the Unphosphorylated Conserved Asp-focused Charge Interactions
J.Biol.Chem., 289, 2014
6C3N
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Crystal structure of BCL6 BTB domain in complex with compound 7CC5
分子名称: B-cell lymphoma 6 protein, N-(2-phenylethyl)-N'-pyridin-3-ylthiourea
著者Linhares, B, Cheng, H, Xue, F, Cierpicki, T.
登録日2018-01-10
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.53170586 Å)
主引用文献Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
J.Med.Chem., 61, 2018
6CQ1
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BCL6 BTB domain in complex with 15a
分子名称: 2-{6-({[2-(1H-indol-3-yl)ethyl]carbamothioyl}amino)-3-[(4-methylpiperazin-1-yl)methyl]-1H-indol-1-yl}-N-(propan-2-yl)acetamide, B-cell lymphoma 6 protein
著者Linhares, B.M, Cheng, H, Xue, F, Cierpicki, T.
登録日2018-03-14
公開日2019-03-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69921041 Å)
主引用文献Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
J.Med.Chem., 61, 2018

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