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STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR
分子名称:	2-(ACETYL-HYDROXY-AMINO)-4-METHYL-PENTANOIC ACID METHYL ESTER, CALCIUM ION, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A, Tronrud, D.E.
登録日	1983-01-27
公開日	1983-03-09
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor. Biochemistry, 22, 1983

3TMN

THE BINDING OF L-VALYL-L-TRYPTOPHAN TO CRYSTALLINE THERMOLYSIN ILLUSTRATES THE MODE OF INTERACTION OF A PRODUCT OF PEPTIDE HYDROLYSIS
分子名称:	CALCIUM ION, THERMOLYSIN, TRYPTOPHAN, ...
著者	Holden, H.M, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis. J.Biol.Chem., 263, 1988

4TLN

BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称:	CALCIUM ION, L-LEUCYL-HYDROXYLAMINE, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A.
登録日	1982-02-08
公開日	1982-05-26
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis. Biochemistry, 20, 1981

4TMN

SLOW-AND FAST-BINDING INHIBITORS OF THERMOLYSIN DISPLAY DIFFERENT MODES OF BINDING. CRYSTALLOGRAPHIC ANALYSIS OF EXTENDED PHOSPHONAMIDATE TRANSITION-STATE ANALOGUES
分子名称:	CALCIUM ION, N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine, THERMOLYSIN, ...
著者	Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues. Biochemistry, 26, 1987

4PAD

Binding of chloromethyl ketone substrate analogues to crystalline papain
分子名称:	N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide, PAPAIN
著者	Drenth, J.
登録日	1976-11-01
公開日	1977-04-12
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Binding of chloromethyl ketone substrate analogues to crystalline papain. Biochemistry, 15, 1976

5TLN

BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称:	CALCIUM ION, HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A.
登録日	1982-02-08
公開日	1982-05-26
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis. Biochemistry, 20, 1981

2PAD

BINDING OF CHLOROMETHYL KETONE SUBSTRATE ANALOGUES TO CRYSTALLINE PAPAIN
分子名称:	CYSTEINE, PAPAIN
著者	Drenth, J, Kalk, K.H, Swen, H.M.
登録日	1976-11-01
公開日	1977-04-12
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Binding of chloromethyl ketone substrate analogues to crystalline papain. Biochemistry, 15, 1976

2OAT

ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE
分子名称:	1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE, ORNITHINE AMINOTRANSFERASE
著者	Storici, P, Schirmer, T.
登録日	1998-05-07
公開日	1998-12-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine. J.Mol.Biol., 285, 1999

2TMN

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称:	CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ...
著者	Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986

6TMN

Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond
分子名称:	CALCIUM ION, N-[(2R,4S)-4-hydroxy-2-(2-methylpropyl)-4-oxido-7-oxo-9-phenyl-3,8-dioxa-6-aza-4-phosphanonan-1-oyl]-L-leucine, THERMOLYSIN, ...
著者	Tronrud, D.E, Holden, H.M, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond. Science, 235, 1987

1TMN

Binding of n-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography. a novel class of transition-state analogues for zinc peptidases
分子名称:	CALCIUM ION, N-[(1R)-1-carboxy-3-phenylpropyl]-L-leucyl-L-tryptophan, THERMOLYSIN, ...
著者	Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases Biochemistry, 23, 1984

1TLP

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称:	CALCIUM ION, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, THERMOLYSIN, ...
著者	Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986

2OMF

OMPF PORIN
分子名称:	(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MATRIX PORIN OUTER MEMBRANE PROTEIN F
著者	Cowan, S.W.
登録日	1995-02-28
公開日	1995-12-07
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	The Refined Structure of Ompf Porin from E.Coli at 2.4 Angstroms Resolution To be Published

1PAD

Binding of chloromethyl ketone substrate analogues to crystalline papain
分子名称:	ACETYL-ALA-ALA-PHE-ALA-CHLOROMETHYLKETONE INHIBITOR, PAPAIN
著者	Drenth, J, Kalk, K.H, Swen, H.M.
登録日	1976-11-01
公開日	1977-04-12
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Binding of chloromethyl ketone substrate analogues to crystalline papain. Biochemistry, 15, 1976

1LNE

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CADMIUM ION, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LNF

A structural analysis of metal substitutions in thermolysin
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者	Holland, D.R, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LND

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LNB

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, FE (III) ION, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LNC

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LNA

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CALCIUM ION, COBALT (II) ION, DIMETHYL SULFOXIDE, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1MPF

STRUCTURAL AND FUNCTIONAL ALTERATIONS OF A COLICIN RESISTANT MUTANT OF OMPF-PORIN FROM ESCHERICHIA COLI
分子名称:	(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MATRIX PORIN OUTER MEMBRANE PROTEIN F
著者	Schirmer, T.
登録日	1994-08-10
公開日	1995-02-07
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Structural and functional alterations of a colicin-resistant mutant of OmpF porin from Escherichia coli. Proc.Natl.Acad.Sci.USA, 91, 1994

1THL

Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan
分子名称:	CALCIUM ION, N-({1-[(2S)-2-carboxy-4-phenylbutyl]cyclopentyl}carbonyl)-L-tryptophan, THERMOLYSIN, ...
著者	Holland, D.R, Matthews, B.W.
登録日	1993-11-17
公開日	1994-01-31
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex Biochemistry, 33, 1994

3DBK

Pseudomonas aeruginosa elastase with phosphoramidon
分子名称:	CALCIUM ION, Elastase, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ...
著者	McKay, D.B, Overgaard, M.T.
登録日	2008-06-01
公開日	2009-07-07
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.4 Å)
主引用文献	Structure of the Elastase of Pseudomonas aeruginosa Complexed with Phosphoramidon To be Published

1NSJ

CRYSTAL STRUCTURE OF PHOSPHORIBOSYL ANTHRANILATE ISOMERASE FROM THERMOTOGA MARITIMA
分子名称:	PHOSPHATE ION, PHOSPHORIBOSYL ANTHRANILATE ISOMERASE
著者	Hennig, M, Jansonius, J.N.J.
登録日	1996-09-13
公開日	1997-03-12
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structure at 2.0 A resolution of phosphoribosyl anthranilate isomerase from the hyperthermophile Thermotoga maritima: possible determinants of protein stability. Biochemistry, 36, 1997

1PDO

PHOSPHOENOLPYRUVATE-DEPENDENT PHOSPHOTRANSFERASE SYSTEM
分子名称:	MANNOSE PERMEASE
著者	Nunn, R.S, Erni, B, Schirmer, T.
登録日	1996-03-08
公開日	1996-08-01
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structure of the IIA domain of the mannose transporter from Escherichia coli at 1.7 angstroms resolution. J.Mol.Biol., 259, 1996

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