4GWS
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![BU of 4gws by Molmil](/molmil-images/mine/4gws) | Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... | 著者 | Gao, Y, Honzatko, R.B. | 登録日 | 2012-09-03 | 公開日 | 2013-09-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fructose 2,6-bisphosphate Inhibition To be Published
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4GWZ
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4H45
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4H46
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![BU of 4h46 by Molmil](/molmil-images/mine/4h46) | Crystal Structure of AMP complexes of NEM modified Porcine Liver Fructose-1,6-bisphosphatase | 分子名称: | 1-ETHYL-PYRROLIDINE-2,5-DIONE, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, ... | 著者 | Gao, Y, Honzatko, R.B. | 登録日 | 2012-09-16 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Fluorescent 2',3'-O-(2,4,6-trinitrophenyl) (TNP)-AMP Is an Active Site Inhibitor for Porcine Liver Fructose-1,6-bisphosphatase Rather Than Allosteric Inhibitor To be Published
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4GWU
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![BU of 4gwu by Molmil](/molmil-images/mine/4gwu) | Crystal Structure of Fru 2,6-bisphosphate complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION | 著者 | Gao, Y, Honzatko, R.B. | 登録日 | 2012-09-03 | 公開日 | 2013-09-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fru 2,6-bisphosphate Inhibition To be Published
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5WRW
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![BU of 5wrw by Molmil](/molmil-images/mine/5wrw) | Structure of human apo-SRP72 | 分子名称: | SULFATE ION, Signal recognition particle subunit SRP72 | 著者 | Gao, Y, Chen, Z. | 登録日 | 2016-12-04 | 公開日 | 2017-06-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation J Mol Cell Biol, 9, 2017
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5WRV
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![BU of 5wrv by Molmil](/molmil-images/mine/5wrv) | Complex structure of human SRP72/SRP68 | 分子名称: | ACETATE ION, GLYCEROL, SODIUM ION, ... | 著者 | Gao, Y, Chen, Z. | 登録日 | 2016-12-04 | 公開日 | 2017-06-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation J Mol Cell Biol, 9, 2017
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7XLQ
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![BU of 7xlq by Molmil](/molmil-images/mine/7xlq) | Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the ligand-free (apo) state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Gao, Y, Qiu, Y, Wei, Y, Dong, Y, Zhang, X.C, Zhao, Y. | 登録日 | 2022-04-22 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular insights into the gating mechanisms of voltage-gated calcium channel Ca V 2.3. Nat Commun, 14, 2023
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8HR7
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![BU of 8hr7 by Molmil](/molmil-images/mine/8hr7) | Structure of RdrA-RdrB complex | 分子名称: | Adenosine deaminase, Archaeal ATPase | 著者 | Gao, Y. | 登録日 | 2022-12-15 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HRB
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![BU of 8hrb by Molmil](/molmil-images/mine/8hrb) | Structure of tetradecameric RdrA ring in RNA-loading state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase, RNA (5'-R(*GP*UP*CP*CP*AP*GP*CP*GP*UP*CP*AP*UP*CP*GP*CP*UP*GP*GP*AP*C)-3') | 著者 | Gao, Y. | 登録日 | 2022-12-15 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HRC
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![BU of 8hrc by Molmil](/molmil-images/mine/8hrc) | Structure of dodecameric RdrB cage | 分子名称: | Adenosine deaminase | 著者 | Gao, Y. | 登録日 | 2022-12-15 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HR8
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![BU of 8hr8 by Molmil](/molmil-images/mine/8hr8) | Structure of heptameric RdrA ring | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase | 著者 | Gao, Y. | 登録日 | 2022-12-15 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HR9
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![BU of 8hr9 by Molmil](/molmil-images/mine/8hr9) | Structure of tetradecameric RdrA ring | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase | 著者 | Gao, Y. | 登録日 | 2022-12-15 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HRA
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![BU of 8hra by Molmil](/molmil-images/mine/8hra) | Structure of heptameric RdrA ring in RNA-loading state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase, RNA (5'-R(P*GP*UP*CP*CP*AP*GP*CP*GP*UP*CP*AP*UP*CP*GP*CP*UP*GP*GP*AP*C)-3') | 著者 | Gao, Y. | 登録日 | 2022-12-15 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8E2L
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![BU of 8e2l by Molmil](/molmil-images/mine/8e2l) | Structure of Lates calcarifer Twinkle helicase with ATP and DNA | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Gao, Y, Li, Z. | 登録日 | 2022-08-15 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase. Nucleic Acids Res., 50, 2022
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6JZQ
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8FTI
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7BTK
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![BU of 7btk by Molmil](/molmil-images/mine/7btk) | E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA01 | 分子名称: | 4-[[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-2H-indol-1-yl]methyl]benzoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Chen, X, Hu, Y.L, Liu, Q.M, Gao, Y, Yuan, R, Guo, Y. | 登録日 | 2020-04-01 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence. Angew.Chem.Int.Ed.Engl., 60, 2021
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7BRS
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![BU of 7brs by Molmil](/molmil-images/mine/7brs) | E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA02 | 分子名称: | 8-[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-indol-1-ium-1-yl]octanoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Chen, X, Hu, Y.L, Gao, Y, Yuan, R, Guo, Y. | 登録日 | 2020-03-30 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence. Angew.Chem.Int.Ed.Engl., 60, 2021
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7YDS
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![BU of 7yds by Molmil](/molmil-images/mine/7yds) | The structure of the bispecific antibody targeted PD-L1 and 4-1BB | 分子名称: | Anti-PDL1-VH-CH1, Anti-PDL1-VL-CL, Programmed cell death 1 ligand 1 | 著者 | Gao, Y, Zhu, M, Liu, W.T, Cheng, L.S, Zhu, Z.L, Niu, L.W. | 登録日 | 2022-07-04 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A bispecific antibody targeted PD-L1 and 4-1BB induces a potent antitumor immune activity in colorectal cancer without systemic toxicity To Be Published
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6LUM
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![BU of 6lum by Molmil](/molmil-images/mine/6lum) | Structure of Mycobacterium smegmatis succinate dehydrogenase 2 | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ... | 著者 | Gao, Y, Gong, H, Zhou, X, Xiao, Y, Wang, W, Ji, W, Wang, Q, Rao, Z. | 登録日 | 2020-01-29 | 公開日 | 2020-05-27 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF. Nat Commun, 11, 2020
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6IIC
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![BU of 6iic by Molmil](/molmil-images/mine/6iic) | CryoEM structure of Mud Crab Dicistrovirus | 分子名称: | VP1 of Mud crab dicistrovirus, VP2 of Mud crab dicistrovirus, VP3 of Mud crab dicistrovirus, ... | 著者 | Zhang, Q, Gao, Y. | 登録日 | 2018-10-04 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-electron Microscopy Structures of Novel Viruses from Mud CrabScylla paramamosainwith Multiple Infections. J. Virol., 93, 2019
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6IZL
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6JZZ
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![BU of 6jzz by Molmil](/molmil-images/mine/6jzz) | The crystal structure of AAR-C294S in complex with ADO. | 分子名称: | Aldehyde decarbonylase, FE (II) ION, HEXADECAN-1-OL, ... | 著者 | Zhang, H.M, Li, M, Gao, Y. | 登録日 | 2019-05-04 | 公開日 | 2020-04-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.011 Å) | 主引用文献 | Structural insights into catalytic mechanism and product delivery of cyanobacterial acyl-acyl carrier protein reductase. Nat Commun, 11, 2020
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6JZY
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![BU of 6jzy by Molmil](/molmil-images/mine/6jzy) | Crystal structure of AAR with NADPH and stearyl in complex with ADO binding a long chain carbohydrate | 分子名称: | Aldehyde decarbonylase, FE (II) ION, HEXADECAN-1-OL, ... | 著者 | Zhang, H.M, Li, M, Gao, Y. | 登録日 | 2019-05-04 | 公開日 | 2020-04-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into catalytic mechanism and product delivery of cyanobacterial acyl-acyl carrier protein reductase. Nat Commun, 11, 2020
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