5CWJ
 
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5CWP
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5CWQ
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5CWL
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5CWH
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4GMS
 | | Crystal structure of heterosubtypic Fab S139/1 in complex with influenza A H3 hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ... | | 著者 | Lee, P.S, Ekiert, D.C, Wilson, I.A. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4GMT
 | | Crystal structure of heterosubtypic Fab S139/1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ... | | 著者 | Lee, P.S, Ekiert, D.C, Wilson, I.A. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
Proc.Natl.Acad.Sci.USA, 109, 2012
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7SEE
 | | Structure of E. coli LetB delta (Ring6) mutant, Ring1 in the closed state (Model 1) | | 分子名称: | MCE family protein, Intermembrane transport protein YebT chimera, UNKNOWN ATOM OR ION | | 著者 | Vieni, C, Coudray, N, Bhabha, G, Ekiert, D. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Role of Ring6 in the Function of the E. coli MCE Protein LetB.
J.Mol.Biol., 434, 2022
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7SEF
 | | Structure of E. coli LetB delta (Ring6) mutant, Ring 1 in the open state (Model 2, Rings 1-3 only) | | 分子名称: | MCE family protein, Intermembrane transport protein YebT chimera | | 著者 | Vieni, C, Coudray, N, Bhabha, G, Ekiert, D. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Role of Ring6 in the Function of the E. coli MCE Protein LetB.
J.Mol.Biol., 434, 2022
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7UDJ
 | | Crystal structure of designed helical repeat protein RPB_PEW3_R4 bound to PAWx4 peptide | | 分子名称: | 4xPAW peptide, De novo designed helical repeat protein RPB_PEW3_R4 | | 著者 | Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D. | | 登録日 | 2022-03-20 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
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8F6Q
 | | CryoEM structure of designed modular protein oligomer C8-71 | | 分子名称: | C8-71 | | 著者 | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | | 登録日 | 2022-11-17 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
Cell(Cambridge,Mass.), 187, 2024
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8F6R
 | | CryoEM structure of designed modular protein oligomer C6-79 | | 分子名称: | De novo designed oligomeric protein C6-79 | | 著者 | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | | 登録日 | 2022-11-17 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
Cell(Cambridge,Mass.), 187, 2024
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5J8E
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7MI6
 | | Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1 | | 分子名称: | (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ... | | 著者 | Santarossa, C.C, Urnavicius, L, Coudray, N, Ekeirt, D.C, Bhabha, G, Kapoor, T.M. | | 登録日 | 2021-04-16 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
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8SMQ
 | | Crystal Structure of the N-terminal Domain of the Cryptic Surface Protein (CD630_25440) from Clostridium difficile. | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Minasov, G, Shuvalova, L, Brunzelle, J.S, Kiryukhina, O, Wawrzak, Z, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2023-04-26 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Protein target highlights in CASP15: Analysis of models by structure providers.
Proteins, 91, 2023
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8GLT
 | | Backbone model of de novo-designed chlorophyll-binding nanocage O32-15 | | 分子名称: | C2-chlorophyll-comp_O32-15_ctermHis, polyalanine model, C3-comp_O32-15 | | 著者 | Redler, R.L, Ennist, N.M, Wang, S, Baker, D, Ekiert, D.C, Bhabha, G. | | 登録日 | 2023-03-23 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | De novo design of proteins housing excitonically coupled chlorophyll special pairs.
Nat.Chem.Biol., 2024
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4FQM
 | | Structure of B/Brisbane/60/2008 Influenza Hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | 著者 | Dreyfus, C, Laursen, N.S, Wilson, I.A. | | 登録日 | 2012-06-25 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Highly conserved protective epitopes on influenza B viruses.
Science, 337, 2012
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4FQL
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4FQH
 | | Crystal Structure of Fab CR9114 | | 分子名称: | 1,2-ETHANEDIOL, NITRATE ION, antibody CR9114 heavy chain, ... | | 著者 | Dreyfus, C, Wilson, I.A. | | 登録日 | 2012-06-25 | | 公開日 | 2012-08-22 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Highly conserved protective epitopes on influenza B viruses.
Science, 337, 2012
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6WYR
 | | Crystal structure of anti-Muscle Specific Kinase (MuSK) Fab, MuSK1A | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MuSK1A heavy chain, ... | | 著者 | Vieni, C, Ekiert, D. | | 登録日 | 2020-05-13 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis.
J.Exp.Med., 217, 2020
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6WYT
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3LZG
 | | Crystal structure of a 2009 H1N1 influenza virus hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Xu, R, Wilson, I.A. | | 登録日 | 2010-03-01 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
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4W7G
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4NM4
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4NM8
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