4PF7
 
 | | Crystal structure of insulin degrading enzyme complexed with inhibitor | | 分子名称: | (2S)-2-amino-N-{(1S)-1-cyclohexyl-2-[(4-methylphenyl)amino]-2-oxoethyl}-4-(methylselanyl)butanamide, Insulin-degrading enzyme, ZINC ION | | 著者 | Wang, Y, Guo, S. | | 登録日 | 2014-04-28 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.
J.Biol.Chem., 290, 2015
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8F2G
 | | Crystal structure of Hen Egg White Lysozyme at 0.44 GPa | | 分子名称: | Lysozyme C | | 著者 | Marshall, A.C, Boer, S.A, Turner, G, Moggach, S.A, Bond, C.S, Vrielink, A. | | 登録日 | 2022-11-08 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | High-pressure single-crystal diffraction at the Australian Synchrotron.
J.Synchrotron Radiat., 30, 2023
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2YZ3
 | | Crystallographic Investigation of Inhibition Mode of the VIM-2 Metallo-beta-lactamase from Pseudomonas aeruginosa with Mercaptocarboxylate Inhibitor | | 分子名称: | (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID, Metallo-beta-lactamase, SULFATE ION, ... | | 著者 | Yamaguchi, Y, Yamagata, Y, Arakawa, Y, Kurosaki, H. | | 登録日 | 2007-05-02 | | 公開日 | 2008-03-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor.
J.Med.Chem., 50, 2007
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6N4E
 | | hPGDS complexed with a quinoline-3-carboxamide | | 分子名称: | 7-(difluoromethoxy)-N-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]quinoline-3-carboxamide, GLUTATHIONE, Hematopoietic prostaglandin D synthase | | 著者 | Shewchuk, L.M, Ward, P. | | 登録日 | 2018-11-19 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors.
Bioorg. Med. Chem., 27, 2019
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6N69
 | | rat hPGDS complexed with a quinoline | | 分子名称: | GLUTATHIONE, Hematopoietic prostaglandin D synthase, quinoline-3-carbonitrile | | 著者 | Shewchuk, L.M, Cleasby, A. | | 登録日 | 2018-11-26 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors.
Bioorg. Med. Chem., 27, 2019
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7T6X
 | | Cryo-EM structure of full-length hepatitis C virus E1E2 glycoprotein in complex with AR4A, AT12009, and IGH505 Fabs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AR4A Fab, ... | | 著者 | Torrents de la Pena, A, Ward, A.B, Eshun-Wilson, L, Lander, G.C. | | 登録日 | 2021-12-14 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | | 主引用文献 | Structure of the hepatitis C virus E1E2 glycoprotein complex.
Science, 378, 2022
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