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Crystal Structure of Actin-like protein Alp7A
分子名称:	ADENOSINE-5'-DIPHOSPHATE, Alp7A, GLYCEROL, ...
著者	Petek, N.A, Kraemer, J.A, Mullins, R.D, Agard, D.A, DiMaio, F, Baker, D.
登録日	2015-10-20
公開日	2016-11-02
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structure and function of Alp7A reveal both conserved and unique features of plasmid segregation. To Be Published

5TVW

Crystal structure of mitochondrial Hsp90 (TRAP1) with ATP in absence of Mg, hemi-hydrolyzed
分子名称:	ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, COBALT (II) ION, ...
著者	Elnatan, D, Betegon, M, Agard, D.A, Northeast Structural Genomics Consortium (NESG)
登録日	2016-11-10
公開日	2018-03-14
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1. Elife, 6, 2017

5FWK

Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者	Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日	2016-02-17
公開日	2016-07-06
最終更新日	2019-08-21
実験手法	ELECTRON MICROSCOPY (3.9 Å)
主引用文献	Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016

5TTH

Heterodimeric SpyCatcher/SpyTag-fused zebrafish TRAP1 in ATP/ADP-hybrid state
分子名称:	ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, C-terminal SpyCatcher fusion of wildtype zebrafish TNF receptor-associated protein 1, ...
著者	Elnatan, D, Betegon, M, Liu, Y, Agard, D.A, Northeast Structural Genomics Consortium (NESG)
登録日	2016-11-03
公開日	2017-08-23
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1. Elife, 6, 2017

5TVX

Crystal structure of mitochondrial Hsp90 (TRAP1) with ATP in absence of Mg, fully hydrolyzed
分子名称:	ADENOSINE-5'-DIPHOSPHATE, TNF receptor-associated protein 1
著者	Elnatan, D, Betegon, M, Agard, D.A.
登録日	2016-11-10
公開日	2017-10-25
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1. Elife, 6, 2017

5FWP

Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者	Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日	2016-02-18
公開日	2016-10-26
最終更新日	2019-12-18
実験手法	ELECTRON MICROSCOPY (7.2 Å)
主引用文献	Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016

5FWL

Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者	Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日	2016-02-18
公開日	2016-07-06
最終更新日	2019-10-23
実験手法	ELECTRON MICROSCOPY (9 Å)
主引用文献	Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016

5TVU

Crystal structure of mitochondrial Hsp90 (TRAP1) with ATP in absence of Mg
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, TNF receptor-associated protein 1
著者	Elnatan, D, Betegon, M, Agard, D.A.
登録日	2016-11-10
公開日	2018-03-14
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (3.5 Å)
主引用文献	Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1. Elife, 6, 2017

5FWM

Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者	Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日	2016-02-18
公開日	2016-07-06
最終更新日	2019-10-23
実験手法	ELECTRON MICROSCOPY (8 Å)
主引用文献	Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016

2OUA

Crystal Structure of Nocardiopsis Protease (NAPase)
分子名称:	1,4-DIETHYLENE DIOXIDE, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, GLYCEROL, ...
著者	Kelch, B.A, Agard, D.A.
登録日	2007-02-09
公開日	2007-02-20
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Structural and mechanistic exploration of Acid resistance: kinetic stability facilitates evolution of extremophilic behavior J.Mol.Biol., 368, 2007

2PFE

Crystal Structure of Thermobifida fusca Protease A (TFPA)
分子名称:	4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Alkaline serine protease, GLYCEROL, ...
著者	Kelch, B.A, Agard, D.A.
登録日	2007-04-04
公開日	2007-07-03
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.436 Å)
主引用文献	Mesophile versus Thermophile: Insights Into the Structural Mechanisms of Kinetic Stability J.Mol.Biol., 370, 2007

2PRO

PRO REGION OF ALPHA-LYTIC PROTEASE
分子名称:	ALPHA-LYTIC PROTEASE
著者	Sauter, N.K, Mau, T, Rader, S.D, Agard, D.A.
登録日	1998-08-20
公開日	1999-04-27
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Structure of alpha-lytic protease complexed with its pro region. Nat.Struct.Biol., 5, 1998

2IOP

Crystal Structure of Full-length HtpG, the Escherichia coli Hsp90, Bound to ADP
分子名称:	ADENOSINE-5'-DIPHOSPHATE, Chaperone protein htpG
著者	Shiau, A.K, Harris, S.F, Agard, D.A.
登録日	2006-10-10
公開日	2006-11-21
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (3.55 Å)
主引用文献	Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements. Cell(Cambridge,Mass.), 127, 2006

2IOR

Crystal Structure of the N-terminal Domain of HtpG, the Escherichia coli Hsp90, Bound to ADP
分子名称:	ADENOSINE-5'-DIPHOSPHATE, Chaperone protein htpG, HEXANE-1,6-DIOL, ...
著者	Shiau, A.K, Harris, S.F, Agard, D.A.
登録日	2006-10-10
公開日	2006-11-21
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements. Cell(Cambridge,Mass.), 127, 2006

2IOQ

Crystal Structure of full-length HTPG, the Escherichia coli HSP90
分子名称:	Chaperone protein htpG
著者	Shiau, A.K, Harris, S.F, Agard, D.A.
登録日	2006-10-10
公開日	2006-11-21
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (3.5 Å)
主引用文献	Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements. Cell(Cambridge,Mass.), 127, 2006

2H5C

0.82A resolution crystal structure of alpha-lytic protease at pH 5
分子名称:	ALPHA-LYTIC PROTEASE, GLYCEROL, SULFATE ION
著者	Fuhrmann, C.N, Daugherty, M.D, Agard, D.A.
登録日	2006-05-25
公開日	2006-09-26
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (0.82 Å)
主引用文献	Subangstrom crystallography reveals that short ionic hydrogen bonds, and not a His-Asp low-barrier hydrogen bond, stabilize the transition state in serine protease catalysis J.Am.Chem.Soc., 128, 2006

2GQ0

Crystal Structure of the Middle Domain of HtpG, the E. coli Hsp90
分子名称:	Chaperone protein htpG
著者	Harris, S.F, Shiau, A.K, Agard, D.A.
登録日	2006-04-19
公開日	2006-10-31
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements. Cell(Cambridge,Mass.), 127, 2006

3URC

T181G mutant of alpha-Lytic Protease
分子名称:	Alpha-lytic protease, GLYCEROL, SULFATE ION
著者	Kelch, B.A, Agard, D.A.
登録日	2011-11-22
公開日	2012-05-23
最終更新日	2019-07-17
実験手法	X-RAY DIFFRACTION (1.1 Å)
主引用文献	Functional modulation of a protein folding landscape via side-chain distortion. Proc.Natl.Acad.Sci.USA, 109, 2012

3URE

Repack mutant (T181I, W199L, Q210I) of alpha-Lytic Protease
分子名称:	Alpha-lytic protease, SULFATE ION
著者	Kelch, B.A, Agard, D.A.
登録日	2011-11-22
公開日	2012-05-23
最終更新日	2012-07-18
実験手法	X-RAY DIFFRACTION (1.49 Å)
主引用文献	Functional modulation of a protein folding landscape via side-chain distortion. Proc.Natl.Acad.Sci.USA, 109, 2012

3URD

T181A mutant of alpha-Lytic Protease
分子名称:	Alpha-lytic protease, GLYCEROL, SULFATE ION
著者	Kelch, B.A, Agard, D.A.
登録日	2011-11-22
公開日	2012-05-23
最終更新日	2019-07-17
実験手法	X-RAY DIFFRACTION (1.08 Å)
主引用文献	Functional modulation of a protein folding landscape via side-chain distortion. Proc.Natl.Acad.Sci.USA, 109, 2012

1L2J

Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
分子名称:	(R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, ESTROGEN RECEPTOR BETA
著者	Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L.
登録日	2002-02-21
公開日	2002-05-01
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.95 Å)
主引用文献	Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat.Struct.Biol., 9, 2002

1K7B

NMR Solution Structure of sTva47, the Viral-Binding Domain of Tva
分子名称:	SUBGROUP A ROUS SARCOMA VIRUS RECEPTOR PG800 AND PG950
著者	Tonelli, M, Peters, R.J, James, T.L, Agard, D.A.
登録日	2001-10-18
公開日	2001-12-19
最終更新日	2020-02-05
実験手法	SOLUTION NMR
主引用文献	The solution structure of the viral binding domain of Tva, the cellular receptor for subgroup A avian leukosis and sarcoma virus. FEBS Lett., 509, 2001

1P11

CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS
分子名称:	ALPHA-LYTIC PROTEASE, PHOSPHONATE ESTER INHIBITOR A, PHOSPHONATE ESTER INHIBITOR B(TRANSITION STATE), ...
著者	Bone, R, Agard, D.A.
登録日	1990-10-26
公開日	1993-01-15
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.93 Å)
主引用文献	Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. Biochemistry, 30, 1991

1P12

CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS
分子名称:	ALPHA-LYTIC PROTEASE, PHOSPHONATE ESTER INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1990-10-26
公開日	1993-01-15
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. Biochemistry, 30, 1991

1QRW

CRYSTAL STRUCTURE OF AN ALPHA-LYTIC PROTEASE MUTANT WITH ACCELERATED FOLDING KINETICS, R102H/G134S, PH 8
分子名称:	ALHPA-LYTIC PROTEASE, GLYCEROL, SULFATE ION
著者	Derman, A.I, Mau, T, Agard, D.A.
登録日	1999-06-16
公開日	1999-06-18
最終更新日	2021-11-03
実験手法	X-RAY DIFFRACTION (1.2 Å)
主引用文献	A Genetic Screen That Targets Specifically the Folding Transition State of Alpha-Lytic Protease To be Published, 1999

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