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2W7X
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BU of 2w7x by Molmil
Cellular inhibition of checkpoint kinase 2 and potentiation of cytotoxic drugs by novel Chk2 inhibitor PV1019
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, N-[4-[(E)-N-carbamimidamido-C-methyl-carbonimidoyl]phenyl]-7-nitro-1H-indole-2-carboxamide, ...
著者Jobson, A.G, Lountos, G.T, Lorenzi, P.L, Llamas, J, Connelly, J, Tropea, J.E, Onda, A, Kondapaka, S, Zhang, G, Caplen, N.J, Caredellina, J.H, Monks, A, Self, C, Waugh, D.S, Shoemaker, R.H, Pommier, Y.
登録日2009-01-06
公開日2009-09-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Cellular Inhibition of Chk2 Kinase and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor Pv1019.
J.Pharmacol.Exp.Ther., 331, 2009
6U5Z
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BU of 6u5z by Molmil
Cryo-EM structure of E. coli LonA S679A
分子名称: Lon protease
著者Botos, I, Lountos, G.T, Weimin, W, Wlodawer, A.
登録日2019-08-28
公開日2020-02-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery
Curr Res Struct Biol, 1, 2020
1Z5T
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BU of 1z5t by Molmil
Crystal Structure of [d(CGCGAA(Z3dU)(Z3dU)CGCG)]2, Z3dU:5-(3-aminopropyl)-2'-deoxyuridine, in presence of thallium I.
分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*(ZDU)P*(ZDU)P*CP*GP*CP*G)-3', SPERMINE, THALLIUM (I) ION
著者Moulaei, T, Maehigashi, T, Lountos, G.T, Komeda, S, Watkins, D, Stone, M.P, Marky, L.A, Li, J.S, Gold, B, Williams, L.D.
登録日2005-03-19
公開日2005-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of B-DNA with cations tethered in the major groove.
Biochemistry, 44, 2005
6MNU
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BU of 6mnu by Molmil
Crystal structure of Yersinia pestis UDP-glucose pyrophosphorylase
分子名称: 1,2-ETHANEDIOL, UTP--glucose-1-phosphate uridylyltransferase
著者Gibbs, M.E, Lountos, G.T, Gumpena, R, Waugh, D.S.
登録日2018-10-03
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.172 Å)
主引用文献Crystal structure of UDP-glucose pyrophosphorylase from Yersinia pestis, a potential therapeutic target against plague.
Acta Crystallogr.,Sect.F, 75, 2019
6APX
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BU of 6apx by Molmil
Crystal structure of human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the monobody YSX1
分子名称: GLYCEROL, Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Monobody YSX1, ...
著者Gumpena, R, Lountos, G.T, Sreejith, R.K, Tropea, J.E, Cherry, S, Waugh, D.S.
登録日2017-08-18
公開日2017-11-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.491 Å)
主引用文献Crystal structure of the human dual specificity phosphatase 1 catalytic domain.
Protein Sci., 27, 2018
6D65
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BU of 6d65 by Molmil
Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein off7
分子名称: Designed AR protein off7, ETHANOL, GLYCEROL, ...
著者Gumpena, R, Lountos, G.T, Waugh, D.S.
登録日2018-04-20
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.348 Å)
主引用文献MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6D66
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Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16
分子名称: 1,2-ETHANEDIOL, D-ALANINE, DI(HYDROXYETHYL)ETHER, ...
著者Gumpena, R, Waugh, D.S, Lountos, G.T.
登録日2018-04-20
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.226 Å)
主引用文献MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6D67
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BU of 6d67 by Molmil
Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion (maltose bound form) in complex with the designed AR protein mbp3_16
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Designed AR protein mbp3_16, ...
著者Gumpena, R, Lountos, G.T, Waugh, D.S.
登録日2018-04-20
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.
Acta Crystallogr F Struct Biol Commun, 74, 2018
8DVH
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BU of 8dvh by Molmil
Crystal structure of ATP-dependent Lon protease from Bacillus subtillis (BsLonBA)
分子名称: Lon protease 2, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, SODIUM ION
著者Sekula, B, Li, M, Gustchina, A, Wlodawer, A.
登録日2022-07-29
公開日2022-11-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unique Structural Fold of LonBA Protease from Bacillus subtilis, a Member of a Newly Identified Subfamily of Lon Proteases.
Int J Mol Sci, 23, 2022
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