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5F2Y
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BU of 5f2y by Molmil
A de novo designed heptameric coiled coil CC-Hept-homoCys-H-E
分子名称: CC-Hept-hCys-H-E
著者Burton, A.J, Brady, R.L, Woolfson, D.N.
登録日2015-12-02
公開日2016-07-06
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Installing hydrolytic activity into a completely de novo protein framework.
Nat.Chem., 8, 2016
5FV8
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BU of 5fv8 by Molmil
Structure of cJun-FosW coiled coil complex.
分子名称: CJUN, FOSW, GLYCEROL, ...
著者Zaccai, N.R, Mason, J.M, Brady, R.L.
登録日2016-02-03
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Helix-Constrained Fos-Based Peptides Inhibit Oncogenic Activator Protein-1 and Cancer Cell Proliferation
To be Published
5EZ8
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BU of 5ez8 by Molmil
A de novo designed heptameric coiled coil CC-Hept-I-C-I
分子名称: CC-Hept-I-C-I
著者Burton, A.J, Brady, R.L, Woolfson, D.N.
登録日2015-11-26
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Installing hydrolytic activity into a completely de novo protein framework.
Nat.Chem., 8, 2016
2A5B
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BU of 2a5b by Molmil
Avidin complexed with 8-oxodeoxyguanosine
分子名称: 2'-DEOXY-8-OXOGUANOSINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin
著者Conners, R, Hooley, E, Thomas, S, Brady, R.L.
登録日2005-06-30
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
2A5C
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BU of 2a5c by Molmil
Structure of Avidin in complex with the ligand 8-oxodeoxyadenosine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-OXODEOXYADENOSINE, Avidin
著者Conners, R, Hooley, E, Thomas, S, Brady, R.L.
登録日2005-06-30
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
2AA3
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BU of 2aa3 by Molmil
Crystal structure of Plasmodium vivax lactate dehydrogenase complex with APADH
分子名称: ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase, ...
著者Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L.
登録日2005-07-13
公開日2006-01-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
2A94
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BU of 2a94 by Molmil
Structure of Plasmodium falciparum lactate dehydrogenase complexed to APADH.
分子名称: ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase
著者Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L.
登録日2005-07-11
公開日2006-01-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
2A8G
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BU of 2a8g by Molmil
Structure of Avidin in complex with the ligand deoxyguanosine
分子名称: 2'-DEOXY-GUANOSINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin
著者Conners, R, Hooley, E, Thomas, S, Brady, R.L.
登録日2005-07-08
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
2AYG
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BU of 2ayg by Molmil
Crystal structure of HPV6a E2 DNA binding domain bound to an 18 base pair DNA target
分子名称: 5'-D(*GP*CP*AP*AP*CP*CP*GP*AP*AP*TP*TP*CP*GP*GP*TP*TP*GP*C)-3', Regulatory protein E2
著者Hooley, E, Brady, R.L, Gaston, K.
登録日2005-09-07
公開日2006-08-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein.
Nucleic Acids Res., 34, 2006
1XIV
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BU of 1xiv by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 2-({4-chloro-[hydroxy(methoxy)methyl]cyclohexyl}amino)ethane-1,1,2-triol
分子名称: 2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL, GLYCEROL, L-lactate dehydrogenase
著者Conners, R, Cameron, A, Read, J.A, Schambach, F, Sessions, R.B, Brady, R.L.
登録日2004-09-22
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase
MOL.BIOCHEM.PARASITOL., 142, 2005
2AYE
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BU of 2aye by Molmil
Crystal structure of the unliganded E2 DNA Binding Domain from HPV6a
分子名称: GLYCEROL, Regulatory protein E2, SULFATE ION
著者Hooley, E, Brady, R.L, Gaston, K.
登録日2005-09-07
公開日2006-08-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein.
Nucleic Acids Res., 34, 2006
2AYB
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BU of 2ayb by Molmil
Crystal structure of HPV6a E2 DNA Binding Domain bound to a 16 base pair DNA target
分子名称: 5'-D(*CP*AP*AP*CP*CP*GP*AP*AP*TP*TP*CP*GP*GP*TP*TP*G)-3', Regulatory protein E2
著者Hooley, E, Brady, R.L, Gaston, K.
登録日2005-09-07
公開日2006-08-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein.
Nucleic Acids Res., 34, 2006
2A92
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BU of 2a92 by Molmil
Crystal structure of lactate dehydrogenase from Plasmodium vivax: complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase
著者Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L.
登録日2005-07-11
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
7NFJ
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BU of 7nfj by Molmil
A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L28Y.
分子名称: CC-Type2-(LaId)4-L28Y
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFL
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BU of 7nfl by Molmil
An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24N.
分子名称: CC-Type2-(LaId)4-I24N
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFF
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BU of 7nff by Molmil
An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24A.
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CC-Type2-(LaId)4-I24A, GLYCEROL
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFM
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BU of 7nfm by Molmil
An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L21K.
分子名称: CC-Type2-(LaId)4-L21K
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFO
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BU of 7nfo by Molmil
A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17C.
分子名称: CC-Type2-(LaId)4-I17C
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFI
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BU of 7nfi by Molmil
An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L7Y.
分子名称: CC-Type2-(LaId)4-L7Y
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFP
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BU of 7nfp by Molmil
A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17K
分子名称: CC-Type2-(LaId)4-I17K, GLYCEROL
著者Burton, A.J, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFK
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BU of 7nfk by Molmil
An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24S.
分子名称: CC-Type2-(LaId)4-I24S, ISOPROPYL ALCOHOL
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFG
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BU of 7nfg by Molmil
A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L14A.
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CC-Type2-(LaId)4-L14A
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFH
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BU of 7nfh by Molmil
A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(MaId)4.
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CC-Type2-(MaId)4
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
7NFN
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BU of 7nfn by Molmil
A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L21N-I24N.
分子名称: CC-Type2-(LaId)4-L21N-I24N, HEXANE-1,6-DIOL
著者Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N.
登録日2021-02-07
公開日2022-03-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Differential sensing with arrays of de novo designed peptide assemblies.
Nat Commun, 14, 2023
1AD9
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BU of 1ad9 by Molmil
IGG-FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY CTM01
分子名称: IGG CTM01 FAB (HEAVY CHAIN), IGG CTM01 FAB (LIGHT CHAIN), SULFATE ION
著者Banfield, M.J, Brady, R.L.
登録日1997-02-24
公開日1998-02-25
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.
Proteins, 29, 1997

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