6IH8
 
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8SLM
 | | Crystal structure of Deinococcus geothermalis PprI | | 分子名称: | MANGANESE (II) ION, SULFATE ION, Zn dependent hydrolase fused to HTH domain, ... | | 著者 | Zhao, Y, Lu, H. | | 登録日 | 2023-04-23 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | The Deinococcus protease PprI senses DNA damage by directly interacting with single-stranded DNA.
Nat Commun, 15, 2024
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8SLN
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3MOW
 | | Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1 | | 分子名称: | (2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10S,12S,15E,17E)-18-carboxy-16-ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5-oxooctade ca-15,17-dien-1-yl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Zhang, Z.-Y, Liu, S, Yu, Z, Yu, X. | | 登録日 | 2010-04-23 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1
To be Published
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2QLG
 | | mPlum | | 分子名称: | Fluorescent protein plum | | 著者 | Shu, X, Remington, S.J. | | 登録日 | 2007-07-12 | | 公開日 | 2008-07-22 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Studies of Far-Red Emission in mPlum, a Monomeric Red Fluorescent Protein
To be Published
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6J2E
 | | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Ebola virus-derived peptide EBOV-NP1 | | 分子名称: | Beta-2-microglobulin, EBOV-NP1, MHC class I antigen | | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | | 登録日 | 2019-01-01 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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7B3N
 | | AmiP amidase-3 from Thermus parvatiensis | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Cell wall hydrolase, ... | | 著者 | Freitag-Pohl, S, Pohl, E. | | 登録日 | 2020-12-01 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.793 Å) | | 主引用文献 | AmiP from hyperthermophilic Thermus parvatiensis prophage is a thermoactive and ultrathermostable peptidoglycan lytic amidase.
Protein Sci., 32, 2023
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2QLI
 | | mPlum E16Q mutant | | 分子名称: | Fluorescent protein plum | | 著者 | Shu, X, Remington, S.J. | | 登録日 | 2007-07-12 | | 公開日 | 2008-07-22 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | Structural Studies of Far-Red Emission in mPlum, a Monomeric Red Fluorescent Protein
To be Published
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4J6I
 | | Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform | | 分子名称: | 2-methyl-1-(4-{2-[1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl]-4,5-dihydro[1]benzoxepino[5,4-d][1,3]thiazol-8-yl}-1H-pyrazol-1-yl)propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | | 著者 | Murray, J.M, Rouge, L, Wu, P. | | 登録日 | 2013-02-11 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform.
Bioorg.Med.Chem.Lett., 23, 2013
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6J2G
 | | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Ebola virus-derived peptide EBOV-NP2 | | 分子名称: | Beta-2-microglobulin, EBOV-NP2, Ptal-N*01:01 | | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | | 登録日 | 2019-01-01 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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6J2H
 | | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 mutant (Met52 Asp53 Leu54 deleted) in complex with Hendra virus-derived peptide HeV1 | | 分子名称: | Beta-2-microglobulin, HeV1, Ptal-N*01:01 (Met52 Asp53 Leu54 deleted) | | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | | 登録日 | 2019-01-01 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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7FDK
 | | SARS-COV-2 Spike RBDMACSp36 binding to mACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | | 著者 | Wang, X, Cao, L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-25 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2.
Nat Commun, 12, 2021
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7FDH
 | | SARS-COV-2 Spike RBDMACSp25 binding to hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | | 著者 | Wang, X, Cao, L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-25 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2.
Nat Commun, 12, 2021
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7FDI
 | | SARS-COV-2 Spike RBDMACSp36 binding to hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | | 著者 | Wang, X, Cao, L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-25 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2.
Nat Commun, 12, 2021
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7FDG
 | | SARS-COV-2 Spike RBDMACSp6 binding to hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | | 著者 | Wang, X, Cao, L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-25 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2.
Nat Commun, 12, 2021
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6J2D
 | | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1 | | 分子名称: | HeV1, Ptal-N*01:01, beta-2 microglobulin | | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | | 登録日 | 2019-01-01 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.313 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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7BW1
 | | Crystal structure of Steroid 5-alpha-reductase 2 in complex with Finasteride | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-oxo-5-alpha-steroid 4-dehydrogenase 2, SULFATE ION, ... | | 著者 | Xiao, Q, Zhang, C, Wei, Z. | | 登録日 | 2020-04-13 | | 公開日 | 2020-08-05 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of human steroid 5 alpha-reductase 2 with anti-androgen drug finasteride.
Res Sq, 2020
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6IH6
 | | Phosphite Dehydrogenase mutant I151R/P176R/M207A from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide | | 分子名称: | Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Song, X, Feng, Y, Liu, Y, Zhao, Z. | | 登録日 | 2018-09-28 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.491 Å) | | 主引用文献 | Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019
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4FLH
 | | Crystal structure of human PI3K-gamma in complex with AMG511 | | 分子名称: | 4-(2-[(5-fluoro-6-methoxypyridin-3-yl)amino]-5-{(1R)-1-[4-(methylsulfonyl)piperazin-1-yl]ethyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | | 著者 | Whittington, D.A, Tang, J, Yakowec, P. | | 登録日 | 2012-06-14 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511.
J.Med.Chem., 55, 2012
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6J2F
 | | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV2 | | 分子名称: | HeV2, Ptal-N*01:01, beta-2 microglobulin | | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | | 登録日 | 2019-01-01 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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6J2I
 | | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with H17N10 influenza-like virus-derivrd peptide H17N10-NP | | 分子名称: | Beta-2-microglobulin, H17N10-NP, Ptal-N*01:01 | | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | | 登録日 | 2019-01-01 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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6J2J
 | | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with MERS-CoV-derived peptide MERS-CoV-S3 | | 分子名称: | Beta-2-microglobulin, MERS-CoV-S3, Ptal-N*01:01 | | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | | 登録日 | 2019-01-01 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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8X8Q
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8X77
 | | Enterovirus proteinase with host factor | | 分子名称: | 2A protein, Actin-histidine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Gao, X, Cui, S. | | 登録日 | 2023-11-23 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | | 主引用文献 | The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction.
Nat Commun, 15, 2024
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3OLG
 | | Structures of human pancreatic alpha-amylase in complex with acarviostatin III03 | | 分子名称: | (1S,2S,3R,6R)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Qin, X, Ren, L. | | 登録日 | 2010-08-26 | | 公開日 | 2011-04-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of human pancreatic alpha-amylase in complex with acarviostatins: Implications for drug design against type II diabetes.
J.Struct.Biol., 174, 2011
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