6V94
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6V9J
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6V9M
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6VAJ
| Crystal Structure Analysis of human PIN1 | 分子名称: | 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ... | 著者 | Seo, H.-S, Dhe-Paganon, S. | 登録日 | 2019-12-17 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nat.Chem.Biol., 17, 2021
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6VEA
| Structure of the Glutamate-Like Receptor GLR3.2 ligand-binding domain in complex with Glycine | 分子名称: | BETA-MERCAPTOETHANOL, GLYCINE, Glutamate receptor 3.2, ... | 著者 | Gangwar, S.P, Green, M.N, Yoder, J.B, Sobolevsky, A.I. | 登録日 | 2019-12-30 | 公開日 | 2020-09-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Structure of the Arabidopsis Glutamate Receptor-like Channel GLR3.2 Ligand-Binding Domain. Structure, 29, 2021
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6VE8
| Structure of the Glutamate-Like Receptor GLR3.2 ligand-binding domain in complex with Methionine | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Gangwar, S.P, Green, M.N, Yoder, J.B, Sobolevsky, A.I. | 登録日 | 2019-12-30 | 公開日 | 2020-09-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of the Arabidopsis Glutamate Receptor-like Channel GLR3.2 Ligand-Binding Domain. Structure, 29, 2021
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5BWU
| X-RAY CRYSTAL STRUCTURE AT 2.17A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A TRIAZOLOPYRIMIDINONE COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR. | 分子名称: | 1,2-ETHANEDIOL, 2-[(4-bromobenzyl)amino]-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Branched-chain-amino-acid aminotransferase, ... | 著者 | Somers, D.O. | 登録日 | 2015-06-08 | 公開日 | 2015-07-01 | 最終更新日 | 2019-06-12 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits. J.Med.Chem., 58, 2015
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6TD3
| Structure of DDB1 bound to CR8-engaged CDK12-cyclinK | 分子名称: | (2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol, Cyclin-K, Cyclin-dependent kinase 12, ... | 著者 | Bunker, R.D, Petzold, G, Kozicka, Z, Thoma, N.H. | 登録日 | 2019-11-07 | 公開日 | 2020-06-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature, 585, 2020
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6T9M
| Crystal structure of the Chitinase Domain of the Spore Coat Protein CotE from Clostridium difficile | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Peptide in active site, ... | 著者 | Whittingham, J.L, Dodson, E.J, Wilkinson, A.J. | 登録日 | 2019-10-28 | 公開日 | 2020-07-22 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structures of the GH18 domain of the bifunctional peroxiredoxin-chitinase CotE from Clostridium difficile. Acta Crystallogr.,Sect.F, 76, 2020
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5E9J
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5C2C
| GWS1B RubisCO: Form II RubisCO derived from uncultivated Gallionellacea species (unliganded form) | 分子名称: | CHLORIDE ION, Form II RubisCO, MAGNESIUM ION | 著者 | Arbing, M.A, Varaljay, V.A, Satagopan, S, Tabita, F.R. | 登録日 | 2015-06-15 | 公開日 | 2015-12-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Functional metagenomic selection of ribulose 1, 5-bisphosphate carboxylase/oxygenase from uncultivated bacteria. Environ.Microbiol., 18, 2016
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5BWW
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5C10
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5C2D
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6TSB
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6TNS
| PI3K delta in complex with 2methoxyN[2methoxy5(7{[(2R)4(oxetan3 yl)morpholin2yl]methoxy}1,3dihydro2 benzofuran5yl)pyridin3yl]ethane1 sulfonamide | 分子名称: | 2-methoxy-~{N}-[2-methoxy-5-[7-[[(2~{R})-4-(oxetan-3-yl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]ethanesulfonamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 著者 | Convery, M.A, Rowland, P, Henley, Z.A, Barton, N, Down, K. | 登録日 | 2019-12-10 | 公開日 | 2020-01-01 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Optimization of Orally Bioavailable PI3K delta Inhibitors and Identification of Vps34 as a Key Selectivity Target. J.Med.Chem., 63, 2020
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6TPY
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6V8E
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6V8R
| Proteinase K Determined by MicroED Phased by ARCIMBOLDO_SHREDDER | 分子名称: | CALCIUM ION, Proteinase K | 著者 | Richards, L.S, Martynowycz, M.W, Sawaya, M.R, Millan, C. | 登録日 | 2019-12-11 | 公開日 | 2020-08-12 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.6 Å) | 主引用文献 | Fragment-based determination of a proteinase K structure from MicroED data using ARCIMBOLDO_SHREDDER Acta Crystallogr.,Sect.D, 76, 2020
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5E25
| Crystal structure of branched-chain aminotransferase from thermophilic archaea Geoglobus acetivorans complexed with alpha-ketoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, PYRIDOXAL-5'-PHOSPHATE, branched-chain aminotransferase | 著者 | Boyko, K.M, Nikolaeva, A.Y, Stekhanova, T.N, Mardanov, A.V, Rakitin, A.L, Ravin, N.V, Popov, V.O. | 登録日 | 2015-09-30 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Thermostable Branched-Chain Amino Acid Transaminases From the Archaea Geoglobus acetivorans and Archaeoglobus fulgidus : Biochemical and Structural Characterization. Front Bioeng Biotechnol, 7, 2019
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5E8V
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6V78
| OmpK37 porin | 分子名称: | OmpK37 | 著者 | Rocker, A, Lithgow, T. | 登録日 | 2019-12-08 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Global Trends in Proteome Remodeling of the Outer Membrane Modulate Antimicrobial Permeability in Klebsiella pneumoniae. Mbio, 11, 2020
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6V9F
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6V9L
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6VEH
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