6LU6
 
 | | Crystal structure of BPTF-BRD with ligand DCBPin5-2 bound | | 分子名称: | 6-[1-[3-(dimethylamino)propyl]indol-5-yl]-2-methylsulfonyl-N-propyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF | | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | | 登録日 | 2020-01-26 | | 公開日 | 2021-04-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.970063 Å) | | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins
To Be Published
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3KXT
 | | Crystal structure of Sulfolobus Cren7-dsDNA complex | | 分子名称: | 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', Chromatin protein Cren7 | | 著者 | Feng, Y, Wang, J. | | 登録日 | 2009-12-03 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | | 主引用文献 | Crystal structure of the crenarchaeal conserved chromatin protein Cren7 and double-stranded DNA complex
Protein Sci., 19, 2010
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1NJ1
 | | Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus bound to cysteine sulfamoyl adenylate | | 分子名称: | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Proline-tRNA Synthetase, ... | | 著者 | Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A. | | 登録日 | 2002-12-30 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
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5FKP
 | | Crystal structure of the mouse CD1d in complex with the p99 peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN-PRESENTING GLYCOPROTEIN CD1D1, BETA 2 MICROGLOBULIN, ... | | 著者 | Girardi, E, Wang, J, Zajonc, D.M. | | 登録日 | 2015-10-18 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of an Alpha-Helical Peptide and Lipopeptide Bound to the Non-Classical Mhc Class I Molecule Cd1D
J.Biol.Chem., 291, 2016
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1NJ5
 | | Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus bound to proline sulfamoyl adenylate | | 分子名称: | '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Proline-tRNA Synthetase, ... | | 著者 | Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A. | | 登録日 | 2002-12-30 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
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1NJ8
 | | Crystal Structure of Prolyl-tRNA Synthetase from Methanocaldococcus janaschii | | 分子名称: | Proline-tRNA Synthetase | | 著者 | Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A. | | 登録日 | 2002-12-30 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
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5EFI
 | | Crystal structure of mouse CD1d in complex with the p99p lipopeptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Girardi, E, Wang, J, Zajonc, D.M. | | 登録日 | 2015-10-23 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of an alpha-Helical Peptide and Lipopeptide Bound to the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule CD1d.
J.Biol.Chem., 291, 2016
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1NGM
 | | Crystal structure of a yeast Brf1-TBP-DNA ternary complex | | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*AP*CP*AP*TP*TP*TP*TP*TP*TP*TP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*AP*AP*AP*AP*AP*AP*AP*TP*GP*TP*TP*TP*TP*TP*T)-3', Transcription factor IIIB BRF1 subunit, ... | | 著者 | Juo, Z.S, Kassavetis, G.A, Wang, J, Geiduschek, E.P, Sigler, P.B. | | 登録日 | 2002-12-17 | | 公開日 | 2003-03-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Crystal structure of a transcription factor IIIB core interface ternary complex
Nature, 422, 2003
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5ZAL
 | | Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) | | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | | 登録日 | 2018-02-07 | | 公開日 | 2018-05-09 | | 最終更新日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.
Cell, 173, 2018
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8PYI
 | | Human IGF1R with inhibitor 6 | | 分子名称: | 3-[8-azanyl-1-(4-ethoxy-8-fluoranyl-2-phenyl-quinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutan-1-ol, Insulin-like growth factor 1 receptor beta chain | | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | | 登録日 | 2023-07-25 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Human IGF1R with inhibitor 6
To Be Published
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8PYJ
 | | Human IGF1R with inhibitor 8 | | 分子名称: | 5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | | 登録日 | 2023-07-25 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | | 主引用文献 | Human IGF1R with inhibitor 8
To Be Published
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8PYK
 | | Human IGF1R with inhibitor 47 | | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, Insulin-like growth factor 1 receptor beta chain, NICKEL (II) ION | | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | | 登録日 | 2023-07-25 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Human IGF1R with inhibitor 47
To Be Published
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8PYN
 | | Human IGF1R with inhibitor 56 | | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | | 登録日 | 2023-07-25 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Human IGF1R with inhibitor 56
To Be Published
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8PYL
 | | Human IGF1R with inhibitor 53 | | 分子名称: | (5S)-5-methyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | | 登録日 | 2023-07-25 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Human IGF1R with inhibitor 53
To Be Published
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8PYM
 | | Human IGF1R with inhibitor 54 | | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | | 登録日 | 2023-07-25 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.652 Å) | | 主引用文献 | Human IGF1R with inhibitor 54
To Be Published
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5ZAK
 | | Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | | 登録日 | 2018-02-07 | | 公開日 | 2018-05-09 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.
Cell, 173, 2018
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4JFB
 | | Crystal structure of OmpF in C2 with tNCS | | 分子名称: | Outer membrane protein F | | 著者 | Wiseman, B, Kilburg, A, Chaptal, V, Reyes-Meija, G.C, Sarwan, J, Falson, P, Jault, J.M. | | 登録日 | 2013-02-28 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.801 Å) | | 主引用文献 | Stubborn contaminants: influence of detergents on the purity of the multidrug ABC transporter BmrA
PLoS ONE, 9, 2014
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1NJ6
 | | Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus bound to alanine sulfamoyl adenylate | | 分子名称: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Proline-tRNA Synthetase, ... | | 著者 | Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A. | | 登録日 | 2002-12-30 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
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3IGI
 | | Tertiary Architecture of the Oceanobacillus Iheyensis Group II Intron | | 分子名称: | 5'-R(*CP*GP*CP*UP*CP*UP*AP*CP*UP*CP*UP*AP*U)-3', Group IIC intron, MAGNESIUM ION, ... | | 著者 | Toor, N, Keating, K.S, Fedorova, O, Rajashankar, K, Wang, J, Pyle, A.M. | | 登録日 | 2009-07-27 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.125 Å) | | 主引用文献 | Tertiary architecture of the Oceanobacillus iheyensis group II intron.
Rna, 16, 2010
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4N77
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3MNM
 | | Crystal structure of GAE domain of GGA2p from Saccharomyces cerevisiae | | 分子名称: | ADP-ribosylation factor-binding protein GGA2, GLYCEROL, SULFATE ION | | 著者 | Fang, P, Wang, J, Li, X, Niu, L, Teng, M. | | 登録日 | 2010-04-21 | | 公開日 | 2010-09-08 | | 最終更新日 | 2014-03-05 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural basis for the specificity of the GAE domain of yGGA2 for its accessory proteins Ent3 and Ent5
Biochemistry, 49, 2010
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4EAL
 | | Co-crystal of AMPK core with ATP soaked with AMP | | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | | 著者 | Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. | | 登録日 | 2012-03-22 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | | 主引用文献 | AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
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3F4M
 | | Crystal structure of TIPE2 | | 分子名称: | CHLORIDE ION, Tumor necrosis factor, alpha-induced protein 8-like protein 2 | | 著者 | Zhang, X, Wang, J, Shi, Y. | | 登録日 | 2008-11-01 | | 公開日 | 2009-03-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Crystal structure of TIPE2 provides insights into immune homeostasis
Nat.Struct.Mol.Biol., 16, 2009
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2KMI
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2O52
 | | Crystal structure of human RAB4B in complex with GDP | | 分子名称: | BETA-MERCAPTOETHANOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Zhu, H, Tempel, W, Wang, J, Shen, Y, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2006-12-05 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of human RAB4B in complex with GDP
To be Published
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