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3G37
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BU of 3g37 by Molmil
Cryo-EM structure of actin filament in the presence of phosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Wakabayshi, T, Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q.
登録日2009-02-02
公開日2010-11-03
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
6A78
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BU of 6a78 by Molmil
Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the scFv fragment of murine monoclonal antibody B5209B
分子名称: Heavy chain and linker region of the anti-human Robo1 antibody B5209B scFv, Light chain region of the anti-human Robo1 antibody B5209B scFv, Roundabout homolog 1, ...
著者Mizohata, E, Nakayama, T, Kado, Y, Inoue, T.
登録日2018-07-02
公開日2019-01-30
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
8T4B
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BU of 8t4b by Molmil
MD65 N332-GT5 SOSIP in complex with RM_N332_32 Fab and RM20A3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, MD65 N332-GT5 SOSIP gp41, ...
著者Ozorowski, G, Torres, J.L, Ward, A.B.
登録日2023-06-08
公開日2024-05-08
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
7Y7F
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BU of 7y7f by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAC)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7E
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BU of 7y7e by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.41 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7G
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BU of 7y7g by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7H
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BU of 7y7h by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7D
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BU of 7y7d by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7C
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BU of 7y7c by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(G34) and mRNA(GAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
2RQQ
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BU of 2rqq by Molmil
Structure of C-terminal region of Cdt1
分子名称: DNA replication factor Cdt1
著者Jee, J.G, Mizuno, T, Kamada, K, Tochio, H, Hiroaki, H, Hanaoka, F, Shirakawa, M.
登録日2009-10-14
公開日2010-03-23
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable the identification of key residues for binding to replicative helicase Mcm proteins
J.Biol.Chem., 285, 2010
5YFI
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BU of 5yfi by Molmil
Crystal structure of the anti-human prostaglandin E receptor EP4 antibody Fab fragment
分子名称: Heavy chain of Fab fragment, Light chain of Fab fragment, ZINC ION
著者Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T.
登録日2017-09-21
公開日2018-12-05
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
1FLE
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BU of 1fle by Molmil
CRYSTAL STRUCTURE OF ELAFIN COMPLEXED WITH PORCINE PANCREATIC ELASTASE
分子名称: ELAFIN, ELASTASE
著者Tsunemi, M, Matsuura, Y, Sakakibara, S, Katsube, Y.
登録日1996-07-04
公開日1997-01-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
Biochemistry, 35, 1996
1G0D
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BU of 1g0d by Molmil
CRYSTAL STRUCTURE OF RED SEA BREAM TRANSGLUTAMINASE
分子名称: PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE, SULFATE ION
著者Noguchi, K, Ishikawa, K, Yokoyama, K, Ohtsuka, T, Nio, N, Suzuki, E.
登録日2000-10-06
公開日2001-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of red sea bream transglutaminase.
J.Biol.Chem., 276, 2001
4ZY3
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BU of 4zy3 by Molmil
Crystal Structure of Keap1 in Complex with a small chemical compound, K67
分子名称: FORMIC ACID, Kelch-like ECH-associated protein 1, N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide)
著者Fukutomi, T, Iso, T, Suzuki, T, Takagi, K, Mizushima, T, Komatsu, M, Yamamoto, M.
登録日2015-05-21
公開日2016-05-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
Nat Commun, 7, 2016
8TBQ
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BU of 8tbq by Molmil
The crystal structure of human VISTA extra cellular domain in complex with Fab fragment of pH-selective anti-VISTA antibody
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, SNS-101 Fab heavy chain, ...
著者van der Horst, E.H, Mukherjee, A, Thisted, T.
登録日2023-06-29
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.593 Å)
主引用文献The pH-selective anti-VISTA antibody SNS-101 displays a favorable pharmacokinetic and safety profile and promotes anti-tumoral M1 macrophage polarization in PD-1 refractory settings
To Be Published
8H1J
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BU of 8h1j by Molmil
Cryo-EM structure of the TnpB-omegaRNA-target DNA ternary complex
分子名称: Non-target strand, RNA-guided DNA endonuclease TnpB, Target strand, ...
著者Nakagawa, R, Hirano, H, Omura, S, Nureki, O.
登録日2022-10-03
公開日2023-04-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of the transposon-associated TnpB enzyme.
Nature, 616, 2023
2RPP
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BU of 2rpp by Molmil
Solution structure of Tandem zinc finger domain 12 in Muscleblind-like protein 2
分子名称: Muscleblind-like protein 2, ZINC ION
著者Abe, C, Dang, W, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-06-24
公開日2009-05-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the RNA binding domain in the human muscleblind-like protein 2
Protein Sci., 18, 2009
1IUC
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BU of 1iuc by Molmil
Fucose-specific lectin from Aleuria aurantia with three ligands
分子名称: Fucose-specific lectin, SULFATE ION, alpha-L-fucopyranose, ...
著者Fujihashi, M, Peapus, D.H, Kamiya, N, Nagata, Y, Miki, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-01
公開日2003-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal Structure of Fucose-Specific Lectin from Aleuria aurantia Binding Ligands at Three of Its Five Sugar Recognition Sites
Biochemistry, 42, 2003
5WR7
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BU of 5wr7 by Molmil
Crystal structure of Trk-A complexed with a selective inhibitor CH7057288
分子名称: High affinity nerve growth factor receptor, N-tert-butyl-2-[2-[6,6-dimethyl-8-(methylsulfonylamino)-11-oxidanylidene-naphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methyl-pyridine-4-carboxamide
著者Tanaka, H, Blaesse, M, Augustin, M, Goesser, C.
登録日2016-11-30
公開日2017-12-06
最終更新日2018-12-19
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Selective TRK Inhibitor CH7057288 against TRK Fusion-Driven Cancer.
Mol. Cancer Ther., 17, 2018
1IUB
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BU of 1iub by Molmil
Fucose-specific lectin from Aleuria aurantia (Hg-derivative form)
分子名称: CHLORIDE ION, Fucose-specific lectin, MERCURY (II) ION, ...
著者Fujihashi, M, Peapus, D.H, Kamiya, N, Nagata, Y, Miki, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-01
公開日2003-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal Structure of Fucose-Specific Lectin from Aleuria aurantia Binding Ligands at Three of Its Five Sugar Recognition Sites
Biochemistry, 42, 2003
5YRT
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BU of 5yrt by Molmil
Diol dehydratase, AdoCbl/substrate-free, anaerobically-prepared crystal
分子名称: 5'-DEOXYADENOSINE, CALCIUM ION, CHLORIDE ION, ...
著者Shibata, N.
登録日2017-11-10
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Direct Participation of a Peripheral Side Chain of a Corrin Ring in Coenzyme B12Catalysis.
Angew. Chem. Int. Ed. Engl., 57, 2018
5YSN
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BU of 5ysn by Molmil
Ethanolamine ammonia-lyase, AdoCbl/substrate-free
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, Ethanolamine ammonia-lyase heavy chain, ...
著者Shibata, N.
登録日2017-11-14
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Direct Participation of a Peripheral Side Chain of a Corrin Ring in Coenzyme B12Catalysis.
Angew. Chem. Int. Ed. Engl., 57, 2018
5YSH
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BU of 5ysh by Molmil
Diol dehydratase - alpha/T172A mutant complexed with AdoCbl, aerobically-prepared crystal
分子名称: 5'-DEOXYADENOSINE, CALCIUM ION, COBALAMIN, ...
著者Shibata, N.
登録日2017-11-14
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Direct Participation of a Peripheral Side Chain of a Corrin Ring in Coenzyme B12Catalysis.
Angew. Chem. Int. Ed. Engl., 57, 2018
4ITD
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BU of 4itd by Molmil
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation
分子名称: 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*(C6G)P*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Zhang, F, Suzuki, K, Tsunoda, M, Wilkinson, O, Millington, C.L, Williams, D.M, Morishita, E.C, Takenaka, A.
登録日2013-01-18
公開日2013-05-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations
Nucleic Acids Res., 41, 2013
6GF6
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BU of 6gf6 by Molmil
Molecular basis of egg coat filament cross-linking: high-resolution structure of the partially deglycosylated ZP1 ZP-N1 domain homodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Zona pellucida sperm-binding protein 1,Zona pellucida sperm-binding protein 1
著者Nishimura, K, Jovine, L.
登録日2018-04-29
公開日2019-06-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility.
Nat Commun, 10, 2019

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