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8EJI
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BU of 8eji by Molmil
Lassa virus glycoprotein complex (Josiah) bound to 19.7E Fab
分子名称: 19.7E Fab heavy chain, 19.7E Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJG
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BU of 8ejg by Molmil
Structure of lineage VII Lassa virus glycoprotein complex (strain Togo/2016/7082)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein GP1, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJD
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BU of 8ejd by Molmil
Structure of lineage IV Lassa virus glycoprotein complex (strain Josiah)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8ELG
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BU of 8elg by Molmil
Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANAF from OC43 virus
分子名称: ACETATE ION, Beta-2-microglobulin, NQK-OC43 peptide, ...
著者Murdolo, L.D, Gras, S.
登録日2022-09-24
公開日2023-06-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.
Nature, 620, 2023
8ELH
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Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANQF from SARS-CoV-2 virus
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Murdolo, L.D, Gras, S.
登録日2022-09-24
公開日2023-06-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.
Nature, 620, 2023
8EQA
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BU of 8eqa by Molmil
Crystal structure of human anti-N1 neuraminidase 2H08 Fab
分子名称: 2H08 Fab heavy chain, 2H08 Fab light chain, ZINC ION
著者Zhu, X, Wilson, I.A.
登録日2022-10-07
公開日2023-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
8EQC
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BU of 8eqc by Molmil
Crystal structure of human anti-N1 neuraminidase 3H03 Fab
分子名称: 3H03 Fab heavy chain, 3H03 Fab light chain, PHOSPHATE ION
著者Zhu, X, Wilson, I.A.
登録日2022-10-07
公開日2023-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
8EJ9
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BU of 8ej9 by Molmil
Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates
分子名称: 3C-like proteinase nsp5
著者Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J.
登録日2022-09-16
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals.
Acs Cent.Sci., 9, 2023
4NIA
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BU of 4nia by Molmil
Satellite Tobacco Mosaic Virus Refined at room temperature to 1.8 A Resolution using NCS Restraints
分子名称: Coat protein, MAGNESIUM ION, PHOSPHATE ION, ...
著者Larson, S.B, Day, J.S, McPherson, A.
登録日2013-11-05
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Satellite tobacco mosaic virus refined to 1.4 angstrom resolution.
Acta Crystallogr.,Sect.D, 70, 2014
8EJ7
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Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates
分子名称: 3C-like proteinase nsp5
著者Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J.
登録日2022-09-16
公開日2023-05-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals.
Acs Cent.Sci., 9, 2023
8EJJ
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BU of 8ejj by Molmil
Lassa virus glycoprotein complex (Josiah) bound to S370.7 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJE
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BU of 8eje by Molmil
Structure of lineage II Lassa virus glycoprotein complex (strain NIG08-A41)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein GP1, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJF
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BU of 8ejf by Molmil
Structure of lineage V Lassa virus glycoprotein complex (strain Soromba-R)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJH
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BU of 8ejh by Molmil
Lassa virus glycoprotein complex (Josiah) bound to 12.1F Fab
分子名称: 12.1F Fab heavy chain, 12.1F Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Perrett, H.R, Ward, A.B.
登録日2022-09-16
公開日2023-06-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8FWA
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BU of 8fwa by Molmil
Phycocyanin structure from a modular droplet injector for serial femtosecond crystallography
分子名称: C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN, ...
著者Botha, S, Doppler, D.L, Sonker, M, Egatz-Gomez, A, Grieco, A, Zaare, S, Jernigan, R, Meza-Aguilar, J.D, Rabbani, M.T, Manna, A, Alvarez, R, Karpos, K, Cruz Villarreal, J, Nelson, G, Ketawala, G.K, Pey, A.L, Ruiz-Fresneda, M.A, Pacheco-Garcia, J.L, Nazari, R, Sierra, R, Hunter, M.S, Batyuk, A, Kupitz, C.J, Sublett, R.E, Lisova, S, Mariani, V, Boutet, S, Fromme, R, Grant, T.D, Fromme, P, Kirian, R.A, Martin-Garcia, J.M, Ros, A.
登録日2023-01-20
公開日2023-06-28
最終更新日2023-07-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme.
Lab Chip, 23, 2023
8FUC
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BU of 8fuc by Molmil
Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein minor site NLS2
分子名称: Contaminant peptide KKLARE, Importin subunit alpha-1, Matrix protein
著者Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
登録日2023-01-17
公開日2023-01-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
8FF7
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BU of 8ff7 by Molmil
Cytosolic ascorbate peroxidase mutant from Panicum virgatum- ascorbate complex
分子名称: ASCORBIC ACID, Cytosolic ascorbate peroxidase, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhang, B, Kang, C.
登録日2022-12-07
公開日2023-02-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Activity of Cytosolic Ascorbate Peroxidase (APX) from Panicum virgatum against Ascorbate and Phenylpropanoids.
Int J Mol Sci, 24, 2023
8FMA
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BU of 8fma by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C11 multimer
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FF6
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BU of 8ff6 by Molmil
Cytosolic ascorbate peroxidase mutant from Panicum virgatum
分子名称: Cytosolic ascorbate peroxidase, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION
著者Zhang, B, Kang, C.
登録日2022-12-07
公開日2023-02-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Activity of Cytosolic Ascorbate Peroxidase (APX) from Panicum virgatum against Ascorbate and Phenylpropanoids.
Int J Mol Sci, 24, 2023
8FM9
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BU of 8fm9 by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FMB
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Nodavirus RNA replication protein A polymerase domain, local refinement
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FUA
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BU of 8fua by Molmil
Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein NLS1
分子名称: Importin subunit alpha-1, Matrix protein
著者Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
登録日2023-01-17
公開日2023-02-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
8FLN
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BU of 8fln by Molmil
Crystal structure of BTK C481S kinase domain in complex with pirtobrutinib
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, SULFATE ION, ...
著者Cedervall, E.P, Morales, T.H, Allerston, C.K.
登録日2022-12-21
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.334 Å)
主引用文献Preclinical characterization of pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor.
Blood, 142, 2023
8FIU
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Potent long-acting inhibitors targeting HIV-1 capsid based on a versatile quinazolin-4-one scaffold
分子名称: 1,2-ETHANEDIOL, HIV-1 capsid, N-[(1S)-1-{(3P)-3-{4-chloro-3-[(methanesulfonyl)amino]-1-methyl-1H-indazol-7-yl}-7-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-oxo-3,4-dihydroquinazolin-2-yl}-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-3-(difluoromethyl)-5,5-difluoro-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide
著者Nolte, R.T.
登録日2022-12-16
公開日2023-02-15
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Potent Long-Acting Inhibitors Targeting the HIV-1 Capsid Based on a Versatile Quinazolin-4-one Scaffold.
J.Med.Chem., 66, 2023
8FLL
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BU of 8fll by Molmil
Crystal structure of BTK kinase domain in complex with pirtobrutinib
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, SULFATE ION, ...
著者Cedervall, E.P, Morales, T.H, Allerston, C.K.
登録日2022-12-21
公開日2023-03-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Preclinical characterization of pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor.
Blood, 142, 2023

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件を2024-09-25に公開中

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