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2I1T
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BU of 2i1t by Molmil
Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels
分子名称: Jingzhaotoxin-3
著者Liao, Z, Peng, K, Liang, S.
登録日2006-08-15
公開日2006-08-29
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels
To be Published
6DHC
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BU of 6dhc by Molmil
X-ray structure of BACE1 in complex with a bicyclic isoxazoline carboxamide as the P3 ligand
分子名称: (3R,3aR,6aS)-N-[(4R,7S,8S,10R,13S)-8-hydroxy-10,17-dimethyl-7-(2-methylpropyl)-5,11,14-trioxo-13-(propan-2-yl)-2-thia-6,12,15-triazaoctadecan-4-yl]hexahydrofuro[3,2-d][1,2]oxazole-3-carboxamide, Beta-secretase 1, GLYCEROL, ...
著者Mesecar, A.D, Lendy, E.K.
登録日2018-05-19
公開日2018-07-25
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand.
Bioorg. Med. Chem. Lett., 28, 2018
1MVW
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BU of 1mvw by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: RABBIT SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL; LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-09-26
公開日2002-11-20
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.STRUCT.BIOL., 138, 2002
4FJZ
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BU of 4fjz by Molmil
Crystal structure of PI3K-gamma in complex with pyrrolo-pyridine inhibitor 63
分子名称: 1'-[7-fluoro-3-methyl-2-(pyridin-2-yl)quinolin-4-yl]-6'-(morpholin-4-yl)-1',2,2',3,5,6-hexahydrospiro[pyran-4,3'-pyrrolo[3,2-b]pyridine], Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Whittington, D.A, Tang, J, Yakowec, P.
登録日2012-06-12
公開日2012-10-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Discovery and in Vivo Evaluation of Dual PI3K-beta/delta inhibitors
J.Med.Chem., 55, 2012
4FJY
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Crystal structure of PI3K-gamma in complex with quinoline-indoline inhibitor 24f
分子名称: 4-[3,3-dimethyl-6-(morpholin-4-yl)-2,3-dihydro-1H-indol-1-yl]-7-fluoro-3-methyl-2-(pyridin-3-yl)quinoline, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Whittington, D.A, Tang, J, Yakowec, P.
登録日2012-06-12
公開日2012-10-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery and in Vivo Evaluation of Dual PI3K-beta/delta inhibitors
J.Med.Chem., 55, 2012
6D1W
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BU of 6d1w by Molmil
human PKD2 F604P mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2
著者Zheng, W, Yang, X, Bulkley, D, Chen, X.Z, Cao, E.
登録日2018-04-12
公開日2018-06-27
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun, 9, 2018
1PPM
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BU of 1ppm by Molmil
CRYSTALLOGRAPHIC ANALYSIS OF TRANSITION-STATE MIMICS BOUND TO PENICILLOPEPSIN: PHOSPHORUS-CONTAINING PEPTIDE ANALOGUES
分子名称: N-[(benzyloxy)carbonyl]-L-alanyl-N-{(1S)-1-[(R)-[(1R)-1-benzyl-2-methoxy-2-oxoethoxy](hydroxy)phosphoryl]-3-methylbutyl }-L-alaninamide, PENICILLOPEPSIN, SULFATE ION, ...
著者Fraser, M.E, James, M.N.G.
登録日1992-06-01
公開日1993-10-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues.
Biochemistry, 31, 1992
1FFZ
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BU of 1ffz by Molmil
LARGE RIBOSOMAL SUBUNIT COMPLEXED WITH R(CC)-DA-PUROMYCIN
分子名称: 23S RIBOSOMAL RNA, R(P*CP*C*)-D(P*A)-R(P*(PU))
著者Nissen, P, Hansen, J, Ban, N, Moore, P.B, Steitz, T.A.
登録日2000-07-26
公開日2000-08-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structural basis of ribosome activity in peptide bond synthesis.
Science, 289, 2000
1O1E
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BU of 1o1e by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-19
公開日2002-12-04
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.Struct.Biol., 138, 2002
1O19
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BU of 1o19 by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-15
公開日2002-11-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.Struct.Biol., 138, 2002
1O1D
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BU of 1o1d by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-18
公開日2002-12-04
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.Struct.Biol., 138, 2002
1O1F
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BU of 1o1f by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-15
公開日2002-12-04
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.Struct.Biol., 138, 2002
1PPL
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BU of 1ppl by Molmil
CRYSTALLOGRAPHIC ANALYSIS OF TRANSITION-STATE MIMICS BOUND TO PENICILLOPEPSIN: PHOSPHORUS-CONTAINING PEPTIDE ANALOGUES
分子名称: N-(3-methylbutanoyl)-L-valyl-N-{(1S)-1-[(R)-[(1R)-1-benzyl-2-methoxy-2-oxoethoxy](hydroxy)phosphoryl]-3-methylbutyl}-L- valinamide, PENICILLOPEPSIN, SULFATE ION, ...
著者Fraser, M.E, James, M.N.G.
登録日1992-06-01
公開日1993-10-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues.
Biochemistry, 31, 1992
1O1C
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BU of 1o1c by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-18
公開日2002-12-04
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.Struct.Biol., 138, 2002
1O1B
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BU of 1o1b by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-15
公開日2002-12-04
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.Struct.Biol., 138, 2002
1O1G
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BU of 1o1g by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-19
公開日2002-12-11
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular modeling of averaged rigor crossbridges from tomograms of insect flight muscle.
J.Struct.Biol., 138, 2002
1M8Q
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BU of 1m8q by Molmil
Molecular Models of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
分子名称: Skeletal muscle Actin, Skeletal muscle Myosin II, Skeletal muscle Myosin II Essential Light Chain, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-07-25
公開日2002-09-10
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular modeling of averaged rigor crossbridges from tomograms of insect flight muscle.
J.Struct.Biol., 138, 2002
1O18
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BU of 1o18 by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-04
公開日2002-11-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.Struct.Biol., 138, 2002
1O1A
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BU of 1o1a by Molmil
MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE
分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ...
著者Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A.
登録日2002-11-18
公開日2002-12-04
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (70 Å)
主引用文献Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle
J.Struct.Biol., 138, 2002
4EC7
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BU of 4ec7 by Molmil
Cobra NGF in complex with lipid
分子名称: (2S)-1-hydroxy-3-(tetradecanoyloxy)propan-2-yl docosanoate, Venom nerve growth factor
著者Jiang, T, Wang, F, Tong, Q.
登録日2012-03-26
公開日2012-09-12
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional insights into lipid-bound nerve growth factors
Faseb J., 26, 2012
4ER1
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BU of 4er1 by Molmil
THE ACTIVE SITE OF ASPARTIC PROTEINASES
分子名称: ENDOTHIAPEPSIN, N-[(1R,2R,4R)-1-(cyclohexylmethyl)-2-hydroxy-6-methyl-4-{[(2R)-2-methylbutyl]carbamoyl}heptyl]-3-(1H-imidazol-3-ium-4-yl)-N~2~-[3-naphthalen-1-yl-2-(naphthalen-1-ylmethyl)propanoyl]-L-alaninamide
著者Quail, J.W, Cooper, J.B, Szelke, M, Blundell, T.L.
登録日1990-10-14
公開日1991-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The active site of aspartic proteinases
FEBS Lett., 174, 1984
4FLH
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BU of 4flh by Molmil
Crystal structure of human PI3K-gamma in complex with AMG511
分子名称: 4-(2-[(5-fluoro-6-methoxypyridin-3-yl)amino]-5-{(1R)-1-[4-(methylsulfonyl)piperazin-1-yl]ethyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Whittington, D.A, Tang, J, Yakowec, P.
登録日2012-06-14
公開日2012-08-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511.
J.Med.Chem., 55, 2012
4FF5
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BU of 4ff5 by Molmil
Structure basis of a novel virulence factor GHIP a glycosyl hydrolase 25 of Streptococcus pneumoniae participating in host cell invasion
分子名称: 1,2-ETHANEDIOL, Glycosyl hydrolase 25
著者Wang, D.
登録日2012-05-31
公開日2013-07-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural basis of the novel S. pneumoniae virulence factor, GHIP, a glycosyl hydrolase 25 participating in host-cell invasion.
Plos One, 8, 2013
4ER2
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BU of 4er2 by Molmil
The active site of aspartic proteinases
分子名称: ENDOTHIAPEPSIN, PEPSTATIN, SULFATE ION
著者Bailey, D, Veerapandian, B, Cooper, J.B, Blundell, T.L.
登録日1990-10-20
公開日1991-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The active site of aspartic proteinases
FEBS Lett., 174, 1984
4HGS
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Crystal structure of ck1gs with compound 13
分子名称: 2-{2-[(3,4-difluorophenoxy)methyl]-5-methoxypyridin-4-yl}-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Casein kinase I isoform gamma-3
著者Huang, X.
登録日2012-10-08
公開日2012-11-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of ck1gs with compound 13
Acs Med.Chem.Lett

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