2Q2Y
| Crystal Structure of KSP in complex with Inhibitor 1 | 分子名称: | 1-{(3R,3AR)-3-[3-(4-ACETYLPIPERAZIN-1-YL)PROPYL]-8-FLUORO-3-PHENYL-3A,4-DIHYDRO-3H-PYRAZOLO[5,1-C][1,4]BENZOXAZIN-2-YL}ETHANONE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | 著者 | Yan, Y. | 登録日 | 2007-05-29 | 公開日 | 2007-09-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 17, 2007
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1QHB
| VANADIUM BROMOPEROXIDASE FROM RED ALGA CORALLINA OFFICINALIS | 分子名称: | CALCIUM ION, HALOPEROXIDASE, PHOSPHATE ION | 著者 | Isupov, M.N, Dalby, A.R, Brindley, A.A, Littlechild, J.A. | 登録日 | 1999-05-11 | 公開日 | 2000-07-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of dodecameric vanadium-dependent bromoperoxidase from the red algae Corallina officinalis. J.Mol.Biol., 299, 2000
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2H0A
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7DDA
| Envelope protein VP37 a crystal structure from White Spot Syndrome Virus | 分子名称: | Envelope protein, SULFATE ION | 著者 | Somsoros, W, Sangawa, T, Takebe, K, Attarataya, J, Suzuki, M, Khunrae, P. | 登録日 | 2020-10-28 | 公開日 | 2021-06-23 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Crystal structure of the C-terminal domain of envelope protein VP37 from white spot syndrome virus reveals sulphate binding sites responsible for heparin binding. J.Gen.Virol., 102, 2021
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2DQS
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2ZBG
| Calcium pump crystal structure with bound AlF4 and TG in the absence of calcium | 分子名称: | MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Toyoshima, C, Ogawa, H, Norimatsu, Y. | 登録日 | 2007-10-20 | 公開日 | 2007-12-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ZBD
| Crystal Structure of the SR Calcium Pump with Bound Aluminium Fluoride, ADP and Calcium | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Toyoshima, C, Nomura, H, Tsuda, T, Ogawa, H, Norimatsu, Y. | 登録日 | 2007-10-20 | 公開日 | 2007-11-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues Nature, 432, 2004
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2RQL
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2ROH
| The DNA binding domain of RTBP1 | 分子名称: | Telomere binding protein-1 | 著者 | Lee, W, Ko, S. | 登録日 | 2008-03-22 | 公開日 | 2009-03-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the DNA binding domain of rice telomere binding protein RTBP1 Biochemistry, 48, 2009
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2TRM
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7EXK
| An AA9 LPMO of Ceriporiopsis subvermispora | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nguyen, H, Kondo, K, Nagata, T, Katahira, M, Mikami, B. | 登録日 | 2021-05-27 | 公開日 | 2022-05-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Functional and Structural Characterizations of Lytic Polysaccharide Monooxygenase, Which Cooperates Synergistically with Cellulases, from Ceriporiopsis subvermispora. Acs Sustain Chem Eng, 10, 2022
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2ZBF
| Calcium pump crystal structure with bound BeF3 and TG in the absence of calcium | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | Toyoshima, C, Ogawa, H, Norimatsu, Y. | 登録日 | 2007-10-20 | 公開日 | 2007-12-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump Proc.Natl.Acad.Sci.Usa, 104, 2007
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2EAT
| Crystal structure of the SR CA2+-ATPASE with bound CPA and TG | 分子名称: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Takahashi, M, Kondou, Y, Toyoshima, C. | 登録日 | 2007-02-02 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104, 2007
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2AGV
| Crystal structure of the SR CA2+-ATPASE with BHQ and TG | 分子名称: | 2,5-DITERT-BUTYLBENZENE-1,4-DIOL, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Toyoshima, C, Obara, K, Norimatsu, Y. | 登録日 | 2005-07-27 | 公開日 | 2005-10-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Inaugural Article: Structural role of countertransport revealed in Ca2+ pump crystal structure in the absence of Ca2+. Proc.Natl.Acad.Sci.USA, 102, 2005
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2EAR
| P21 crystal of the SR CA2+-ATPase with bound TG | 分子名称: | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, ... | 著者 | Takahashi, M, Kondou, Y, Toyoshima, C. | 登録日 | 2007-02-02 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104, 2007
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5X02
| Crystal structure of the FLT3 kinase domain bound to the inhibitor FF-10101 | 分子名称: | N-[(2S)-1-[5-[2-[(4-cyanophenyl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxidanylidene-propan-2-yl]-4-(dimethylamino)-N-methyl-but-2-enamide, Receptor-type tyrosine-protein kinase FLT3, SULFATE ION | 著者 | Fujikawa, N, Hirano, D, Takasaki, M, Terada, D, Hagiwara, S, Park, S.-Y, Sugiyama, K. | 登録日 | 2017-01-19 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells withFLT3mutations. Blood, 131, 2018
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5ZR3
| Crystal structure of Hsp90-alpha N-terminal domain in complex with 4-(3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)-3-methylbenzamide | 分子名称: | 3-methyl-4-{4-[4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl]-3-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzamide, Heat shock protein HSP 90-alpha | 著者 | Uno, T, Chong, K.T, Suzuki, T. | 登録日 | 2018-04-23 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1 H-pyrazol-4-yl)-1 H-imidazol-1-yl)-1 H-pyrazolo[3,4- b]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor. J. Med. Chem., 62, 2019
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2ZBE
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2EAU
| Crystal structure of the SR CA2+-ATPASE with bound CPA in the presence of curcumin | 分子名称: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, PHOSPHATIDYLETHANOLAMINE, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 著者 | Takahashi, M, Kondou, Y, Toyoshima, C. | 登録日 | 2007-02-02 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104, 2007
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1FN3
| CRYSTAL STRUCTURE OF NICKEL RECONSTITUTED HEMOGLOBIN-A CASE FOR PERMANENT, T-STATE HEMOGLOBIN | 分子名称: | HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, PROTOPORPHYRIN IX CONTAINING NI(II) | 著者 | Venkateshrao, S, Deepthi, S, Pattabhi, V, Manoharan, P.T. | 登録日 | 2000-08-20 | 公開日 | 2003-10-07 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Crystal Structure of Nickel Reconstituted Hemoglobin - A Case for Permanent, T-State Hemoglobin CURR.SCI., 84, 2003
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7E9J
| Crystal Structure of POMGNT2 in complex with UDP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, ... | 著者 | Kuwabara, N. | 登録日 | 2021-03-04 | 公開日 | 2021-05-05 | 最終更新日 | 2021-07-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structure of POMGNT2 provides new insights into the mechanism to determine the functional O-mannosylation site on alpha-dystroglycan. Genes Cells, 26, 2021
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7E9L
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7E9K
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4KJD
| RatIntestinal AP expressed in E. coli | 分子名称: | GLYCEROL, Intestinal-type alkaline phosphatase 1, MAGNESIUM ION | 著者 | Ghosh, K, Anumula, R.K, Laksmaiah, B.K. | 登録日 | 2013-05-03 | 公開日 | 2013-10-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Crystal structure of rat intestinal alkaline phosphatase - Role of crown domain in mammalian alkaline phosphatases. J.Struct.Biol., 184, 2013
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4KJG
| Structure of Rat Intestinal Alkaline Phosphatase expressed in insect cell | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ghosh, K, Anumula, R.K, Laksmaiah, B.K. | 登録日 | 2013-05-03 | 公開日 | 2013-10-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal structure of rat intestinal alkaline phosphatase - Role of crown domain in mammalian alkaline phosphatases. J.Struct.Biol., 184, 2013
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