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8JA0
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BU of 8ja0 by Molmil
Cryo-EM structure of the NmeCas9-sgRNA-AcrIIC4 ternary complex
分子名称: CRISPR-associated endonuclease Cas9, RNA (117-MER), Uncharacterized protein
著者Yin, H, Li, Z, Yu, G.M, Li, X.Z.
登録日2023-05-05
公開日2023-08-09
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Inhibitory mechanism of CRISPR-Cas9 by AcrIIC4.
Nucleic Acids Res., 51, 2023
6JZA
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BU of 6jza by Molmil
Structure of Fstl1
分子名称: Follistatin-related protein 1
著者Liu, X, Ning, W.
登録日2019-04-30
公開日2019-08-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional study of FK domain of Fstl1.
Protein Sci., 28, 2019
8VH5
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BU of 8vh5 by Molmil
Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 dimer state
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION, ...
著者Zhu, H, Sun, J.
登録日2023-12-30
公開日2024-10-09
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献RAB12-LRRK2 complex suppresses primary ciliogenesis and regulates centrosome homeostasis in astrocytes.
Nat Commun, 15, 2024
8VH4
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BU of 8vh4 by Molmil
Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 monomer state
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION, ...
著者Zhu, H, Sun, J.
登録日2023-12-30
公開日2024-10-09
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献RAB12-LRRK2 complex suppresses primary ciliogenesis and regulates centrosome homeostasis in astrocytes.
Nat Commun, 15, 2024
7YEY
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BU of 7yey by Molmil
Structure of MmIGF2BP3-KH12 in complex with 8-mer RNA
分子名称: Insulin-like growth factor 2 mRNA-binding protein 3, RNA (5'-R(*CP*AP*CP*GP*GP*CP*AP*C)-3')
著者Li, X.J, Wu, B.X.
登録日2022-07-06
公開日2023-07-12
最終更新日2025-03-05
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for the RNA binding properties of mouse IGF2BP3.
Structure, 2025
7YEW
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BU of 7yew by Molmil
Structure of MmIGF2BP3 in complex with 7-mer RNA
分子名称: Insulin-like growth factor 2 mRNA-binding protein 3, RNA (5'-R(P*CP*AP*CP*AP*CP*AP*C)-3')
著者Li, X.J, Wu, B.X.
登録日2022-07-06
公開日2023-07-12
最終更新日2025-03-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the RNA binding properties of mouse IGF2BP3.
Structure, 2025
7YEX
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BU of 7yex by Molmil
Structure of MmIGF2BP3 in complex with 8-mer RNA
分子名称: Insulin-like growth factor 2 mRNA-binding protein 3, RNA (5'-R(P*CP*AP*CP*AP*CP*AP*CP*A)-3')
著者Li, X.J, Wu, B.X.
登録日2022-07-06
公開日2023-07-12
最終更新日2025-03-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the RNA binding properties of mouse IGF2BP3.
Structure, 2025
1BBA
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BU of 1bba by Molmil
SEQUENCE-SPECIFIC 1H NMR ASSIGNMENTS AND SOLUTION STRUCTURE OF BOVINE PANCREATIC POLYPEPTIDE
分子名称: BOVINE PANCREATIC POLYPEPTIDE
著者Li, X, Sutcliffe, M.J, Schwartz, T.W, Dobson, C.M.
登録日1992-03-10
公開日1993-10-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Sequence-specific 1H NMR assignments and solution structure of bovine pancreatic polypeptide.
Biochemistry, 31, 1992
6K32
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BU of 6k32 by Molmil
RdRp complex
分子名称: 2'-O-methyladenosine 5'-(dihydrogen phosphate), 7-METHYLGUANOSINE, DIPHOSPHATE, ...
著者Li, X.W.
登録日2019-05-16
公開日2019-11-20
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of RdRps Within a Transcribing dsRNA Virus Provides Insights Into the Mechanisms of RNA Synthesis.
J.Mol.Biol., 432, 2020
8TYV
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BU of 8tyv by Molmil
Crystal structure of the SPX domain of XPR1 in complex with IP8
分子名称: (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], Solute carrier family 53 member 1
著者Wang, H, Shears, S.B.
登録日2023-08-25
公開日2024-06-12
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8.
Cell Rep, 43, 2024
8TYU
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BU of 8tyu by Molmil
High-resolution crystal structure of the SPX domain of XPR1 at 1.4 angstroms
分子名称: Solute carrier family 53 member 1
著者Wang, H, Shears, S.B.
登録日2023-08-25
公開日2024-06-12
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8.
Cell Rep, 43, 2024
3SRU
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BU of 3sru by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: Dihydrofolate reductase, N-[3'-(2,4-diaminoquinazolin-7-yl)-4'-ethoxybiphenyl-3-yl]methanesulfonamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-07
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
3SRR
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BU of 3srr by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: 3-(2,4-diamino-6-methylquinazolin-7-yl)-4-ethoxybenzaldehyde, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-07
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
3SQY
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BU of 3sqy by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: 7-(2-methoxyphenyl)quinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-06
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
3SR5
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BU of 3sr5 by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: 7-(3,4-dimethoxyphenyl)-6-methylquinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-06
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
3SRW
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BU of 3srw by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: 7-(2-ethoxynaphthalen-1-yl)-6-methylquinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-07
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
3SRQ
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BU of 3srq by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: 1-[3-(2,4-diamino-6-methylquinazolin-7-yl)phenyl]ethanone, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-07
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
3SRS
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BU of 3srs by Molmil
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
分子名称: 7-(5-bromo-2-ethoxyphenyl)-6-methylquinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hilgers, M.
登録日2011-07-07
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg.Med.Chem.Lett., 21, 2011
7VSJ
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BU of 7vsj by Molmil
Crystal structure of MmIMP3-RRM12 in complex with 9-mer RNA
分子名称: Insulin-like growth factor 2 mRNA-binding protein 3, RNA (9-mer)
著者Li, X.J, Wu, B.X.
登録日2021-10-26
公開日2022-11-02
最終更新日2025-03-05
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural basis for the RNA binding properties of mouse IGF2BP3.
Structure, 2025
7WW3
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BU of 7ww3 by Molmil
Crystal structure of MmIMP1-KH34 tandem domain
分子名称: Insulin-like growth factor 2 mRNA-binding protein 1
著者Li, X.J, Wu, B.X.
登録日2022-02-12
公開日2023-02-22
最終更新日2025-03-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the RNA binding properties of mouse IGF2BP3.
Structure, 2025
7VKL
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BU of 7vkl by Molmil
Crystal structure of MmIMP3-KH12 in complex with zipcode RNA
分子名称: Insulin-like growth factor 2 mRNA-binding protein 3, RNA (8-mer)
著者Li, X.J, Wu, B.X.
登録日2021-09-30
公開日2022-10-05
最終更新日2025-03-05
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for the RNA binding properties of mouse IGF2BP3.
Structure, 2025
5YS2
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BU of 5ys2 by Molmil
Structure of the domain IV(D_IV) of Pseudorabies virus glycoprotein B( PRV gB)
分子名称: Envelope glycoprotein B,Envelope glycoprotein B
著者Hu, X.L, Yang, F.L.
登録日2017-11-12
公開日2017-12-27
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design.
PLoS Pathog., 13, 2017
5YSL
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BU of 5ysl by Molmil
Crystal structure of antibody 1H1 Fab
分子名称: 1H1 heavy chain, 1H1 light chain
著者Hu, X.L, Yang, F.L.
登録日2017-11-14
公開日2017-12-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design.
PLoS Pathog., 13, 2017
8K82
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BU of 8k82 by Molmil
Cryo-EM structure of the yeast 80S ribosome with tigecycline, Not5 and P-site tRNA
分子名称: 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ...
著者Buschauer, R, Beckmann, R, Cheng, J.
登録日2023-07-28
公開日2024-07-10
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
7VKP
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BU of 7vkp by Molmil
Crystal structure of E.coli pseudouridine kinase PsuK
分子名称: PfkB domain protein
著者Li, K.J, Li, X.J, Wu, B.X.
登録日2021-09-30
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure Characterization of Escherichia coli Pseudouridine Kinase PsuK.
Front Microbiol, 13, 2022

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