4USP
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![BU of 4usp by Molmil](/molmil-images/mine/4usp) | X-ray structure of the dimeric CCL2 lectin in native form | 分子名称: | CCL2 LECTIN, CHLORIDE ION, PHOSPHATE ION | 著者 | Bleuler-Martinez, S, Varrot, A, Schubert, M, Stutz, M, Sieber, R, Hengartner, M, Aebi, M, Kunzler, M. | 登録日 | 2014-07-11 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes. Glycobiology, 27, 2017
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7BFY
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5MAY
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![BU of 5may by Molmil](/molmil-images/mine/5may) | STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 2-Thiophenesulfonamide-N-(beta-L-fucopyranosyl methyl) | 分子名称: | CALCIUM ION, Fucose-binding lectin PA-IIL, N-methyl-2-thiophenesulfonamide, ... | 著者 | Sommer, R, Imberty, A, Titz, A, Varrot, A. | 登録日 | 2016-11-07 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa. J. Am. Chem. Soc., 140, 2018
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5MB1
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![BU of 5mb1 by Molmil](/molmil-images/mine/5mb1) | STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 2,4,6-Trimethylphenylsulfonamide-N-methyl-L-fucopyranoside | 分子名称: | CALCIUM ION, CITRATE ANION, Fucose-binding lectin PA-IIL, ... | 著者 | Sommer, R, Imberty, A, Titz, A, Varrot, A. | 登録日 | 2016-11-07 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa. J. Am. Chem. Soc., 140, 2018
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5MAZ
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![BU of 5maz by Molmil](/molmil-images/mine/5maz) | STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 3-Thiophenesulfonamide-2,5-dimethyl-N-methyl-beta-L-fucopyranoside | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Fucose-binding lectin PA-IIL, ... | 著者 | Sommer, R, Imberty, A, Titz, A, Varrot, A. | 登録日 | 2016-11-07 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Discovery of a new class of C-glycoside based inhibitors of the virulence factor LecB from Pseudomonas aeruginosa To Be Published
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3ZW1
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![BU of 3zw1 by Molmil](/molmil-images/mine/3zw1) | Structure of Bambl lectine in complex with lewix x antigen | 分子名称: | BAMBL LECTIN, alpha-D-galactopyranose, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Audfray, A, Claudinon, J, Abounit, S, Ruvoen-Clouet, N, Larson, G, Wimmerova, M, Lependu, J, Romer, W, Varrot, A, Imberty, A. | 登録日 | 2011-07-28 | 公開日 | 2011-11-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Deciphering the Glycan Preference of Bacterial Lectins by Glycan Array and Molecular Docking with Validation by Microcalorimetry and Crystallography. Plos One, 8, 2013
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3ZWE
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![BU of 3zwe by Molmil](/molmil-images/mine/3zwe) | Structure of BambL, a lectin from Burkholderia ambifaria, complexed with blood group B epitope | 分子名称: | BAMBL LECTIN, alpha-L-fucopyranose, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | 著者 | Audfray, A, Claudinon, J, Abounit, S, Ruvoen-Clouet, N, Larson, G, Wimmerova, M, LePendu, J, Romer, W, Varrot, A, Imberty, A. | 登録日 | 2011-07-29 | 公開日 | 2011-12-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Fucose-Binding Lectin from Opportunistic Pathogen Burkholderia Ambifaria Binds to Both Plant and Human Oligosaccharidic Epitopes. J.Biol.Chem., 287, 2012
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3ZW2
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![BU of 3zw2 by Molmil](/molmil-images/mine/3zw2) | Structure of the lectin Bambl from Burkholderia ambifaria in complex with blood group H type 1 tetrasaccharide | 分子名称: | BAMBL LECTIN, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Audfray, A, Claudinon, J, Abounit, S, Ruvoen-Clouet, N, Larson, G, Wimmerova, M, Lependu, J, Romer, W, Varrot, A, Imberty, A. | 登録日 | 2011-07-28 | 公開日 | 2011-11-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Fucose-Binding Lectin from Opportunistic Pathogen Burkholderia Ambifaria Binds to Both Plant and Human Oligosaccharidic Epitopes. J.Biol.Chem., 287, 2012
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3ZW0
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![BU of 3zw0 by Molmil](/molmil-images/mine/3zw0) | Structure of BambL lectin from Burkholderia ambifaria | 分子名称: | BAMBL LECTIN, alpha-L-fucopyranose | 著者 | Audfray, A, Claudinon, J, Abounit, S, Ruvoen-Clouet, N, Larson, G, Wimmerova, M, LePendu, J, Romer, W, Varrot, A, Imberty, A. | 登録日 | 2011-07-28 | 公開日 | 2011-12-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Fucose-Binding Lectin from Opportunistic Pathogen Burkholderia Ambifaria Binds to Both Plant and Human Oligosaccharidic Epitopes. J.Biol.Chem., 287, 2012
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6R35
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![BU of 6r35 by Molmil](/molmil-images/mine/6r35) | Structure of the LecB lectin from Pseudomonas aeruginosa strain PAO1 in complex with lewis x tetrasaccharide | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Fucose-binding lectin PA-IIL, ... | 著者 | Lepsik, M, Sommer, R, Kuhaudomlarp, S, Lelimousin, M, Varrot, A, Titz, A, Imberty, A. | 登録日 | 2019-03-19 | 公開日 | 2019-06-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study. Eur.J.Med.Chem., 177, 2019
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4I6S
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![BU of 4i6s by Molmil](/molmil-images/mine/4i6s) | Structure of RSL mutant W76A in complex with L-fucose | 分子名称: | 1,2-ETHANEDIOL, Putative fucose-binding lectin protein, TETRAETHYLENE GLYCOL, ... | 著者 | Audfray, A, Arnaud, J, Varrot, A, Imberty, A. | 登録日 | 2012-11-30 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Reduction of lectin valency drastically changes glycolipid dynamics in membranes but not surface avidity Acs Chem.Biol., 8, 2013
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5MB4
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1E5J
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![BU of 1e5j by Molmil](/molmil-images/mine/1e5j) | ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN THE TETRAGONAL CRYSTAL FORM IN COMPLEX WITH METHYL-4II-S-ALPHA-CELLOBIOSYL-4II-THIO-BETA-CELLOBIOSIDE | 分子名称: | CALCIUM ION, ENDOGLUCANASE 5A, alpha-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside | 著者 | Fort, S, Varrot, A, Schulein, M, Cottaz, S, Driguez, H, Davies, G.J. | 登録日 | 2000-07-26 | 公開日 | 2001-07-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mixed-Linkage Cellooligosaccharides: A New Class of Glycoside Hydrolase Inhibitors Chembiochem, 2, 2001
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3ZVX
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![BU of 3zvx by Molmil](/molmil-images/mine/3zvx) | STRUCTURE OF THE LECTIN FROM PLATYPODIUM ELEGANS IN COMPLEX WITH A TRIMANNOSIDE | 分子名称: | CALCIUM ION, GLYCEROL, LECTIN, ... | 著者 | Benevides, R.G, Ganne, G, Unverzagt, C, Cavada, B.S, Breton, C, Varrot, A, Imberty, A. | 登録日 | 2011-07-28 | 公開日 | 2012-01-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Lectin from Platypodium Elegans with Unusual Specificity and Affinity for Asymmetric Complex N-Glycans. J.Biol.Chem., 287, 2012
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3ZYR
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![BU of 3zyr by Molmil](/molmil-images/mine/3zyr) | Structure of the lectin from Platypodium elegans in complex with heptasaccharide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARAGINE, CALCIUM ION, ... | 著者 | Benevides, R.G, Ganne, G, Cavazza, B.S, Varrot, A, Imberty, A. | 登録日 | 2011-08-24 | 公開日 | 2012-01-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A Lectin from Platypodium Elegans with Unusual Specificity and Affinity for Asymmetric Complex N-Glycans. J.Biol.Chem., 287, 2012
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6A3H
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![BU of 6a3h by Molmil](/molmil-images/mine/6a3h) | 2-DEOXY-2-FLURO-B-D-CELLOTRIOSYL/ENZYME INTERMEDIATE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.6 ANGSTROM RESOLUTION | 分子名称: | ENDOGLUCANASE, GLYCEROL, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose | 著者 | Davies, G.J, Varrot, A, Dauter, M, Brzozowski, A.M, Schulein, M, Mackenzie, L, Withers, S.G. | 登録日 | 1998-07-22 | 公開日 | 1999-07-24 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase. Biochemistry, 37, 1998
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4UP4
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![BU of 4up4 by Molmil](/molmil-images/mine/4up4) | Structure of the recombinant lectin PVL from Psathyrella velutina in complex with GlcNAcb-D-1,3Galactoside | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ... | 著者 | Audfray, A, Beljoudi, M, Hurbin, A, Varrot, A, Breiman, A, Busser, B, Lependu, J, Coll, J.L, Imberty, A. | 登録日 | 2014-06-12 | 公開日 | 2015-01-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A Recombinant Fungal Lectin for Labeling Truncated Glycans on Human Cancer Cells. Plos One, 10, 2015
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5FSC
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![BU of 5fsc by Molmil](/molmil-images/mine/5fsc) | Structure of tectonin 2 from Laccaria bicolor in complex with allyl- alpha_4-methyl-mannoside | 分子名称: | MAGNESIUM ION, TECTONIN 2, prop-2-en-1-yl 4-O-methyl-alpha-D-mannopyranoside | 著者 | Sommer, R, Bleuer, S, Titz, A, Kunzler, M, Varrot, A. | 登録日 | 2016-01-04 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense. Structure, 26, 2018
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7QE3
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![BU of 7qe3 by Molmil](/molmil-images/mine/7qe3) | Se-M variant of B-trefoil lectin from Salpingoeca rosetta in complex with GalNAc | 分子名称: | (2S)-hexane-1,2,6-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose, ... | 著者 | Notova, S, Varrot, A. | 登録日 | 2021-12-01 | 公開日 | 2022-09-14 | 最終更新日 | 2022-09-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3. Commun Biol, 5, 2022
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7QE4
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![BU of 7qe4 by Molmil](/molmil-images/mine/7qe4) | B-trefoil lectin from Salpingoeca rosetta in complex with GalNAc | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, CHLORIDE ION, ... | 著者 | Notova, S, Varrot, A. | 登録日 | 2021-12-01 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3. Commun Biol, 5, 2022
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7R55
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![BU of 7r55 by Molmil](/molmil-images/mine/7r55) | B-trefoil lectin from Salpingoeca rosetta in complex with Gb3 | 分子名称: | 1,2-ETHANEDIOL, Sarol-1, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Notova, S, Varrot, A. | 登録日 | 2022-02-10 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3. Commun Biol, 5, 2022
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5G3L
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![BU of 5g3l by Molmil](/molmil-images/mine/5g3l) | ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER COMPLEXED WITH SIALYLATED SUGAR | 分子名称: | HEAT-LABILE ENTEROTOXIN IIB, B CHAIN, N-acetyl-alpha-neuraminic acid, ... | 著者 | Zalem, D, Benktander, J, Ribeiro, J.P, Varrot, A, Lebens, M, Imberty, A, Teneberg, S. | 登録日 | 2016-04-29 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Biochemical and Structural Characterization of the Novel Sialic Acid-Binding Site of Escherichia Coli Heat-Labile Enterotoxin Lt-Iib. Biochem.J., 473, 2016
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1DYS
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![BU of 1dys by Molmil](/molmil-images/mine/1dys) | Endoglucanase CEL6B from Humicola insolens | 分子名称: | ENDOGLUCANASE | 著者 | Davies, G.J, Brzozowski, A.M, Dauter, M, Varrot, A, Schulein, M. | 登録日 | 2000-02-08 | 公開日 | 2001-02-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure and Function of Humicola Insolens Family 6 Cellulases: Structure of the Endoglucanase, Cel6B, at 1.6 A Resolution Biochem.J., 348, 2000
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3ZI8
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![BU of 3zi8 by Molmil](/molmil-images/mine/3zi8) | Structure of the R17A mutant of the Ralstonia soleanacerum lectin at 1.5 Angstrom in complex with L-fucose | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, MAGNESIUM ION, PUTATIVE FUCOSE-BINDING LECTIN PROTEIN, ... | 著者 | Arnaud, J, Audfray, A, Claudinon, J, Trondle, K, Trosvalet, M, Thomas, A, Varrot, A, Romer, W, Imberty, A. | 登録日 | 2013-01-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Reduction of Lectin Valency Drastically Changes Glycolipid Dynamics in Membranes, But not Surface Avidity. Acs Chem.Biol., 8, 2013
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8R8A
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![BU of 8r8a by Molmil](/molmil-images/mine/8r8a) | |