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Cryo-EM structure of HIV-1 Env(CH848 10.17 DS.SOSIP_DT) in complex with DH1030.1 Fab
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1030.1 Fab Heavy chain, ...
著者	Gobeil, S, Acharya, P.
登録日	2022-07-14
公開日	2023-07-19
実験手法	ELECTRON MICROSCOPY (3.69 Å)
主引用文献	Shared recognition mechanism for HIV-1 envelope-reactive V3 glycan broadly neutralizing B cell lineage maturation in humans and macaques To Be Published

8DTK

Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Fab Heavy Chain, DH1047 Fab Light Chain, ...
著者	May, A.J, Manne, K, Acharya, P.
登録日	2022-07-25
公開日	2023-08-02
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (3.77 Å)
主引用文献	Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates. Biorxiv, 2023

7L6M

Cryo-EM structure of DH898.1 Fab-dimer from local refinement of the Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer
分子名称:	DH898.1 Fab heavy chain, DH898.1 Fab light chain
著者	Manne, K, Edwards, R.J, Acharya, P.
登録日	2020-12-23
公開日	2021-02-10
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (4.7 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7L02

Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to one copy of domain-swapped antibody 2G12
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ...
著者	Manne, K, Henderson, R, Acharya, P.
登録日	2020-12-10
公開日	2020-12-30
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7L09

Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound domain-swapped antibody 2G12 from masked 3D refinement
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ...
著者	Manne, K, Henderson, R, Acharya, P.
登録日	2020-12-11
公開日	2020-12-30
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7KE9

SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.08 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KEB

SARS-CoV-2 D614G 1RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.48 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDH

SARS-CoV-2 RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-08
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.33 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDI

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer fully cleaved by furin without the P986-P987 stabilizing mutations (S-RRAR-D614G)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-08
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.26 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KEA

SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.33 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDG

SARS-CoV-2 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-08
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.01 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDL

SARS-CoV-2 D614G 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-08
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (2.96 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KE8

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2022-02-02
実験手法	ELECTRON MICROSCOPY (3.26 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7L6O

Cryo-EM structure of HIV-1 Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 - gp120, ...
著者	Manne, K, Edwards, R.J, Acharya, P.
登録日	2020-12-23
公開日	2021-04-14
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (3.9 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7LUA

Cryo-EM structure of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 SOSIP gp120, ...
著者	Manne, K, Edwards, R.J, Acharya, P.
登録日	2021-02-21
公開日	2021-03-17
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (4.7 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7LU9

Cryo-EM structure of DH851.3 bound to HIV-1 CH505 Env
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Manne, K, Edwards, R.J, Acharya, P.
登録日	2021-02-21
公開日	2021-03-24
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (5.6 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7LWJ

Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.24 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWI

Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.07 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWM

Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (2.83 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWW

Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 1-RBD-up conformation (S-GSAS-D614G-K417N-E484K-N501Y)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWO

Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (2.85 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYM

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-07
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.57 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWT

UK (B.1.1.7) SARS-CoV-2 spike protein variant (S-GSAS-B.1.1.7) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.19 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWU

UK (B.1.1.7) SARS-CoV-2 spike protein variant (S-GSAS-B.1.1.7) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.22 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWV

UK (B.1.1.7) SARS-CoV-2 spike protein variant (S-GSAS-B.1.1.7) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.12 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

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