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2ZO9
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BU of 2zo9 by Molmil
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal ion preference
分子名称: FE (II) ION, MALONATE ION, Phosphohydrolase
著者Jackson, C.J, Carr, P.D, Ollis, D.L.
登録日2008-05-07
公開日2008-10-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference.
Acta Crystallogr.,Sect.F, 64, 2008
2ZOA
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BU of 2zoa by Molmil
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) COLLECTED AT 1.280 ANGSTROM
分子名称: FE (II) ION, MALONATE ION, Phosphohydrolase
著者Ollis, D.L, Jackson, C.J, Carr, P.D.
登録日2008-05-07
公開日2008-10-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference.
Acta Crystallogr.,Sect.F, 64, 2008
6U9H
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BU of 6u9h by Molmil
Arabidopsis thaliana acetohydroxyacid synthase complex
分子名称: Acetolactate synthase small subunit 2, chloroplastic, Acetolactate synthase, ...
著者Guddat, L.W, Low, Y.S, Rao, Z.
登録日2019-09-08
公開日2020-07-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of fungal and plant acetohydroxyacid synthases.
Nature, 586, 2020
7KE2
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BU of 7ke2 by Molmil
Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg2+ and NSC116565
分子名称: 6-hydroxy-2-methyl[1,3]thiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION
著者Kurz, J.L, Patel, K.P, Guddat, L.W.
登録日2020-10-09
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Discovery of a Pyrimidinedione Derivative with Potent Inhibitory Activity against Mycobacterium tuberculosis Ketol-Acid Reductoisomerase.
Chemistry, 27, 2021
3A4J
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BU of 3a4j by Molmil
arPTE (K185R/D208G/N265D/T274N)
分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, Phosphotriesterase
著者Foo, J.L, Jackson, C.J, Carr, P.D, Ollis, D.L.
登録日2009-07-07
公開日2010-01-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase
Proc.Natl.Acad.Sci.USA, 2009
7KH7
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BU of 7kh7 by Molmil
Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg2+, NADPH, and NSC116565
分子名称: 6-hydroxy-2-methyl[1,3]thiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, ...
著者Kurz, J.L, Patel, K.P, Guddat, L.W.
登録日2020-10-20
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Discovery of a Pyrimidinedione Derivative with Potent Inhibitory Activity against Mycobacterium tuberculosis Ketol-Acid Reductoisomerase.
Chemistry, 27, 2021
6U9D
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BU of 6u9d by Molmil
Saccharomyces cerevisiae acetohydroxyacid synthase
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Acetolactate synthase catalytic subunit, mitochondrial, ...
著者Guddat, L.W, Lonhienne, T.
登録日2019-09-08
公開日2020-07-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.194 Å)
主引用文献Structures of fungal and plant acetohydroxyacid synthases.
Nature, 586, 2020
6VZ8
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BU of 6vz8 by Molmil
Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound
分子名称: Acetolactate synthase small subunit 2, chloroplastic, Acetolactate synthase, ...
著者Guddat, L.W, Low, Y.S.
登録日2020-02-27
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structures of fungal and plant acetohydroxyacid synthases.
Nature, 586, 2020
6VO2
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BU of 6vo2 by Molmil
Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg, NADPH and inhibitor.
分子名称: 3-(methylsulfonyl)-2-oxopropanoic acid, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, ...
著者Bayaraa, T, Patel, K.M, Guddat, L.W.
登録日2020-01-29
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Discovery, Synthesis and Evaluation of a Ketol-Acid Reductoisomerase Inhibitor.
Chemistry, 26, 2020
6WO1
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BU of 6wo1 by Molmil
Hybrid acetohydroxyacid synthase complex structure with Cryptococcus neoformans AHAS catalytic subunit and Saccharomyces cerevisiae AHAS regulatory subunit
分子名称: 2-methylpyrimidin-4-amine, Acetohydroxyacid synthase catalytic subunit, Acetohydroxyacid synthase regulatory subunit, ...
著者Guddat, L.W, Lonhienne, T.
登録日2020-04-23
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of fungal and plant acetohydroxyacid synthases.
Nature, 586, 2020
6G46
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BU of 6g46 by Molmil
Red kidney bean purple acid phosphatase in complex with 2-(Naphthalen-1-yl)thiazole-4-carboxylic acid
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-naphthalen-1-yl-1,3-thiazole-4-carboxylic acid, ...
著者Feder, D.F.
登録日2018-03-26
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics.
Eur J Med Chem, 157, 2018
8SWM
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BU of 8swm by Molmil
Crystal structure of Campylobacter jejuni ketol-acid reductoisomerase in complex with 2-acetolactate
分子名称: (2S)-2-hydroxy-2-methyl-3-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase (NADP(+)), ...
著者Lin, X, Lonhienne, T, Guddat, L.W.
登録日2023-05-19
公開日2024-04-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8SXD
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BU of 8sxd by Molmil
Campylobacter jejuni keto-acid reductoisomerase in complex with intermediate and NADP+
分子名称: 3-hydroxy-3-methyl-2-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase, ...
著者Lin, X, Lonhienne, T, Guddat, L.W.
登録日2023-05-21
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8UPP
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BU of 8upp by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with NADPH and Hoe704
分子名称: (2R)-(dimethylphosphoryl)(hydroxy)acetic acid, Ketol-acid reductoisomerase, MAGNESIUM ION, ...
著者Lin, X, Lv, Y, Lonhienne, T, Guddat, L.W.
登録日2023-10-23
公開日2024-04-24
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8UPN
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BU of 8upn by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with NADP+ and HMKB
分子名称: 3-hydroxy-3-methyl-2-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase, ...
著者Lin, X, Lonhienne, T, Guddat, L.W.
登録日2023-10-23
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8UPQ
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BU of 8upq by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with 2,3-dihydroxy-3-isovalerate.
分子名称: (2R)-2,3-dihydroxy-3-methylbutanoic acid, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION
著者Lin, X, Lonhienne, T, Guddat, L.W.
登録日2023-10-23
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
7LAT
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BU of 7lat by Molmil
Campylobacter jejuni keto-acid reductoisomerase in complex with Mg2+
分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION
著者Guddat, L.W.
登録日2021-01-06
公開日2022-01-12
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
7MY6
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BU of 7my6 by Molmil
Se-CrtE C-term His-tag with IPP added
分子名称: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, ...
著者Peat, T.S, Newman, J.
登録日2021-05-20
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MXZ
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BU of 7mxz by Molmil
Sy-CrtE apo structure
分子名称: CHLORIDE ION, Geranylgeranyl pyrophosphate synthase, MAGNESIUM ION
著者Peat, T.S, Newman, J.
登録日2021-05-19
公開日2022-06-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MY1
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BU of 7my1 by Molmil
Sy-CrtE structure with IPP, N-term His-tag
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, Geranylgeranyl pyrophosphate synthase, ...
著者Peat, T.S, Newman, J.
登録日2021-05-19
公開日2022-06-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MY7
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BU of 7my7 by Molmil
Se-CrtE N-term His-tag structure
分子名称: Farnesyl-diphosphate synthase
著者Peat, T.S, Newman, J.
登録日2021-05-20
公開日2022-06-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MY0
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BU of 7my0 by Molmil
Sy-CrtE IPP structure
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Geranylgeranyl pyrophosphate synthase, ...
著者Peat, T.S, Newman, J.
登録日2021-05-19
公開日2022-06-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
4NON
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BU of 4non by Molmil
Crystal structure of GDP-bound A143S mutant of the S. thermophilus FeoB G-domain
分子名称: Ferrous iron uptake transporter protein B, GUANOSINE-5'-DIPHOSPHATE
著者Guilfoyle, A.P, Deshpande, C.N, Jormakka, M.
登録日2013-11-20
公開日2014-04-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional analysis of a FeoB A143S G5 loop mutant explains the accelerated GDP release rate.
Febs J., 281, 2014
4Q00
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BU of 4q00 by Molmil
Crystal structure of an S150A mutant of the E. coli FeoB G-domain
分子名称: Ferrous iron transport protein B, SULFATE ION
著者Jormakka, M, Guilfoyle, A.P, Deshpande, C.N.
登録日2014-03-31
公開日2015-02-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release.
Biosci.Rep., 34, 2014
4Q5I
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BU of 4q5i by Molmil
Crystal structure of a T151A mutant of the E. coli FeoB G-domain
分子名称: Ferrous iron transport protein B, SULFATE ION
著者Jormakka, M, Guilfoyle, A.P, Deshpande, C.N, Maher, M.
登録日2014-04-17
公開日2015-04-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release.
Biosci.Rep., 34, 2014

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