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6CJR
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BU of 6cjr by Molmil
Candida albicans Hsp90 nucleotide binding domain in complex with SNX-2112
分子名称: 1,2-ETHANEDIOL, 4-[6,6-dimethyl-4-oxidanylidene-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-oxidanylcyclohexyl)amino]benzamide, Heat shock protein 90 homolog
著者Kirkpatrick, M.G, Pizarro, J.C.
登録日2018-02-26
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
Nat Commun, 10, 2019
6CJJ
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Candida albicans Hsp90 nucleotide binding domain in complex with ADP
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Heat shock protein 90 homolog, ...
著者Hutchinson, A, Loppnau, P, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, STRUCTURAL GENOMICS CONSORTIUM, S.G.C, Pizarro, J.C, Structural Genomics Consortium (SGC)
登録日2018-02-26
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
Nat Commun, 10, 2019
6CJS
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BU of 6cjs by Molmil
Candida albicans Hsp90 nucleotide binding domain in complex with AUY922
分子名称: 1,2-ETHANEDIOL, 5-[2,4-DIHYDROXY-5-(1-METHYLETHYL)PHENYL]-N-ETHYL-4-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ISOXAZOLE-3-CARBOXAMIDE, Heat shock protein 90 homolog
著者Kirkpatrick, M.G, Pizarro, J.C.
登録日2018-02-26
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
Nat Commun, 10, 2019
6CJP
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BU of 6cjp by Molmil
Candida albicans Hsp90 nucleotide binding domain in complex with radicicol
分子名称: (1aR,2Z,4E,6E,14R,15aR)-9,11-dihydroxy-6-{[(4-methoxyphenyl)methoxy]imino}-14-methyl-1a,6,7,14,15,15a-hexahydro-12H-oxireno[e][2]benzoxacyclotetradecin-12-one, Heat shock protein 90 homolog
著者Nation, C, Pizarro, J.C.
登録日2018-02-26
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
Nat Commun, 10, 2019
6CJL
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BU of 6cjl by Molmil
Candida albicans Hsp90 nucleotide binding domain in complex with radicicol
分子名称: Heat shock protein 90 homolog, MAGNESIUM ION, RADICICOL
著者Nation, C, Pizarro, J.C.
登録日2018-02-26
公開日2019-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6972 Å)
主引用文献Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
Nat Commun, 10, 2019
3KHE
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BU of 3khe by Molmil
Crystal structure of the calcium-loaded calmodulin-like domain of the CDPK, 541.m00134 from toxoplasma gondii
分子名称: CALCIUM ION, Calmodulin-like domain protein kinase isoform 3, GLYCEROL, ...
著者Wernimont, A.K, Hutchinson, A, Artz, J.D, Mackenzie, F, Cossar, D, Kozieradzki, I, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Qiu, W, Amani, M, Structural Genomics Consortium (SGC)
登録日2009-10-30
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of parasitic CDPK domains point to a common mechanism of activation.
Proteins, 79, 2011
3D8H
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BU of 3d8h by Molmil
Crystal structure of phosphoglycerate mutase from Cryptosporidium parvum, cgd7_4270
分子名称: Glycolytic phosphoglycerate mutase
著者Wernimont, A.K, Lew, J, Wasney, G, Alam, Z, Kozieradzki, I, Cossar, D, Schapiro, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Wilkstrom, M, Edwards, A.M, Hui, R, Artz, J.D, Hills, T, Structural Genomics Consortium (SGC)
登録日2008-05-23
公開日2008-07-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Characterization of a new phosphatase from Plasmodium.
Mol.Biochem.Parasitol., 179, 2011
2J4W
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BU of 2j4w by Molmil
Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12.19 complex
分子名称: APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19
著者Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
登録日2006-09-07
公開日2007-01-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation.
J.Mol.Biol., 366, 2007
3FW5
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BU of 3fw5 by Molmil
Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with Ferric 4-methyl-catechol
分子名称: 4-METHYLCATECHOL, CHLORIDE ION, FE (III) ION, ...
著者Clifton, M.C, Strong, R.K.
登録日2009-01-16
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.
Nat.Chem.Biol., 6, 2010
3OMZ
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BU of 3omz by Molmil
Crystal structure of MICA-specific human gamma delta T cell receptor
分子名称: human Vdelta1 gamma delta T cell receptor delta1A/B-3
著者Xu, B, Holmes, M.A, Strong, R.K.
登録日2010-08-27
公開日2011-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Crystal structure of a {gamma}{delta} T-cell receptor specific for the human MHC class I homolog MICA.
Proc.Natl.Acad.Sci.USA, 108, 2011
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