3FW4

Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with Ferric Catechol

Summary for 3FW4

• Entry DOI: 10.2210/pdb3fw4/pdb
• Related: 3FW5
• Descriptor: Neutrophil gelatinase-associated lipocalin, FE (III) ION, CATECHOL, ... (7 entities in total)
• Functional Keywords: 8-stranded anti-parallel beta barrel, 310-helix, glycoprotein, pyrrolidone carboxylic acid, secreted, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P80188
• Total number of polymer chains: 3
• Total formula weight: 63491.67

Authors

Clifton, M.C.,Strong, R.K. (deposition date: 2009-01-16, release date: 2010-05-05, Last modification date: 2023-09-06)

• Primary citation: Bao, G.,Clifton, M.,Hoette, T.M.,Mori, K.,Deng, S.X.,Qiu, A.,Viltard, M.,Williams, D.,Paragas, N.,Leete, T.,Kulkarni, R.,Li, X.,Lee, B.,Kalandadze, A.,Ratner, A.J.,Pizarro, J.C.,Schmidt-Ott, K.M.,Landry, D.W.,Raymond, K.N.,Strong, R.K.,Barasch, J.; Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.; Nat.Chem.Biol., 6:602-609, 2010; PubMed: 20581821; DOI: 10.1038/nchembio.402

Experimental method

X-RAY DIFFRACTION (2.3 Å)