5USL
 
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5USH
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7ZC4
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7PZP
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7PZR
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6YR8
 | | Affimer K6 - KRAS protein complex | | 分子名称: | Affimer K6, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C. | | 登録日 | 2020-04-19 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
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6YXW
 | | Affimer K3 - KRAS protein complex | | 分子名称: | Affimer K3, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C. | | 登録日 | 2020-05-04 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
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1H0A
 | | Epsin ENTH bound to Ins(1,4,5)P3 | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, EPSIN | | 著者 | Ford, M.G.J, McMahon, H.T, Evans, P.R. | | 登録日 | 2002-06-12 | | 公開日 | 2002-10-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Curvature of Clathrin-Coated Pits Driven by Epsin
Nature, 419, 2002
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6ZDB
 | | NMR structural analysis of yeast Cox13 reveals its C-terminus in interaction with ATP | | 分子名称: | Cytochrome c oxidase subunit 13, mitochondrial | | 著者 | Shu, Z, Pontus, P, Peter, B, Lena, M, Pia, A. | | 登録日 | 2020-06-14 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structural analysis of the yeast cytochrome c oxidase subunit Cox13 and its interaction with ATP.
Bmc Biol., 19, 2021
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6LUL
 | | NMR structure and dynamics studies of yeast respiratory super-complex factor 2 in micelles | | 分子名称: | Respiratory supercomplex factor 2, mitochondrial | | 著者 | Zhou, S, Pontus, P, Peter, B, Maler, L, Adelroth, P. | | 登録日 | 2020-01-29 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure and Dynamics Studies of Yeast Respiratory Supercomplex Factor 2.
Structure, 29, 2021
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7NY8
 | | Affimer K69 - KRAS protein complex | | 分子名称: | Affimer K69, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Turner, A.L, Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C. | | 登録日 | 2021-03-21 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
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3PTG
 | | Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor | | 分子名称: | C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 10, N-[4-methyl-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide | | 著者 | Bowers, S, Truong, A.P, Neitz, J, Neitzel, M, Probst, G.D, Hom, R.K, Konradi, A.W, Sham, H.L, Toth, G, Pan, H, Yao, N, Artis, D.R, Brigham, E.F, Quinn, K.P, Sauer, J, Powell, K, Ruslim, L, Bard, F, Yednock, T.A, Griswold-Prenner, I. | | 登録日 | 2010-12-02 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor.
Bioorg.Med.Chem.Lett., 21, 2011
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2A8Q
 | | 2.6 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29 and Manganese in the Presence of 7-methyl-GDP | | 分子名称: | MANGANESE (II) ION, PYROPHOSPHATE 2-, U8 snoRNA-binding protein X29 | | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | | 登録日 | 2005-07-08 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes
Structure, 14, 2006
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2A8S
 | | 2.45 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29, Manganese and GTP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, U8 snoRNA-binding protein X29 | | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | | 登録日 | 2005-07-08 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes
Structure, 14, 2006
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2A8R
 | | 2.45 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29 and Manganese in the Presence of 7-methyl-GTP | | 分子名称: | MANGANESE (II) ION, PYROPHOSPHATE 2-, U8 snoRNA-binding protein X29 | | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | | 登録日 | 2005-07-08 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes
Structure, 14, 2006
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2A8P
 | | 2.7 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29 and Manganese | | 分子名称: | MANGANESE (II) ION, U8 snoRNA-binding protein X29 | | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | | 登録日 | 2005-07-08 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes
Structure, 14, 2006
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2A8T
 | | 2.1 Angstrom Crystal Structure of the Complex Between the Nuclear U8 snoRNA Decapping Nudix Hydrolase X29, Manganese and m7G-PPP-A | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE, MANGANESE (II) ION, ... | | 著者 | Scarsdale, J.N, Peculis, B.A, Wright, H.T. | | 登録日 | 2005-07-08 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes
Structure, 14, 2006
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