1GC6
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![BU of 1gc6 by Molmil](/molmil-images/mine/1gc6) | CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN | 著者 | Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. | 登録日 | 2000-07-21 | 公開日 | 2000-09-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
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2DPX
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![BU of 2dpx by Molmil](/molmil-images/mine/2dpx) | Crystal Structure of human Rad GTPase | 分子名称: | GTP-binding protein RAD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Yanuar, A, Sakurai, S, Kitano, K, Hakoshima, T. | 登録日 | 2006-05-18 | 公開日 | 2006-08-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of human Rad GTPase of the RGK-family Genes Cells, 11, 2006
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1QQ2
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![BU of 1qq2 by Molmil](/molmil-images/mine/1qq2) | CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23. | 分子名称: | CHLORIDE ION, THIOREDOXIN PEROXIDASE 2 | 著者 | Hirotsu, S, Abe, Y, Okada, K, Nagahara, N, Hori, H, Nishino, T, Hakoshima, T. | 登録日 | 1999-06-10 | 公開日 | 1999-10-29 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product. Proc.Natl.Acad.Sci.USA, 96, 1999
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2E1F
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![BU of 2e1f by Molmil](/molmil-images/mine/2e1f) | Crystal structure of the HRDC Domain of Human Werner Syndrome Protein, WRN | 分子名称: | CHLORIDE ION, Werner syndrome ATP-dependent helicase | 著者 | Kitano, K, Yoshihara, N, Hakoshima, T. | 登録日 | 2006-10-25 | 公開日 | 2006-12-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the HRDC domain of human Werner syndrome protein, WRN J.Biol.Chem., 282, 2007
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1J19
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![BU of 1j19 by Molmil](/molmil-images/mine/1j19) | Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide | 分子名称: | 16-mer peptide from Intercellular adhesion molecule-2, radixin | 著者 | Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T. | 登録日 | 2002-12-02 | 公開日 | 2003-03-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex EMBO J., 22, 2003
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4Y61
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![BU of 4y61 by Molmil](/molmil-images/mine/4y61) | Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta, SLIT and NTRK-like protein 2 | 著者 | Yamgata, A, Sato, Y, Goto-Ito, S, Uemura, T, Maeda, A, Shiroshima, T, Yoshida, T, Fukai, S. | 登録日 | 2015-02-12 | 公開日 | 2015-06-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.358 Å) | 主引用文献 | Structure of Slitrk2-PTP delta complex reveals mechanisms for splicing-dependent trans-synaptic adhesion. Sci Rep, 5, 2015
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4ZKF
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![BU of 4zkf by Molmil](/molmil-images/mine/4zkf) | Crystal structure of human phosphodiesterase 12 | 分子名称: | 2',5'-phosphodiesterase 12, MAGNESIUM ION | 著者 | Kim, S.Y, Kohno, T, Mori, T, Kitano, K, Hakoshima, T. | 登録日 | 2015-04-30 | 公開日 | 2015-06-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal structure of human phosphodiesterase To Be Published
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1A2B
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![BU of 1a2b by Molmil](/molmil-images/mine/1a2b) | HUMAN RHOA COMPLEXED WITH GTP ANALOGUE | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA | 著者 | Ihara, K, Muraguchi, S, Kato, M, Shimizu, T, Shirakawa, M, Kuroda, S, Kaibuchi, K, Hakoshima, T. | 登録日 | 1997-12-26 | 公開日 | 1998-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue. J.Biol.Chem., 273, 1998
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1BDJ
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![BU of 1bdj by Molmil](/molmil-images/mine/1bdj) | COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY | 分子名称: | AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB, CHEY, SULFATE ION | 著者 | Kato, M, Mizuno, T, Shimizu, T, Hakoshima, T. | 登録日 | 1998-05-10 | 公開日 | 1999-05-11 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor protein ArcB complexed with the chemotaxis response regulator CheY. Acta Crystallogr.,Sect.D, 55, 1999
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1DPF
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![BU of 1dpf by Molmil](/molmil-images/mine/1dpf) | CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, RHOA | 著者 | Shimizu, T, Ihara, K, Maesaki, R, Kuroda, S, Kaibuchi, K, Hakoshima, T. | 登録日 | 1999-12-27 | 公開日 | 2000-06-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism. J.Biol.Chem., 275, 2000
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2IRF
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![BU of 2irf by Molmil](/molmil-images/mine/2irf) | CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX. | 分子名称: | DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P*T)-3'), DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A)-3'), INTERFERON REGULATORY FACTOR 2, ... | 著者 | Fujii, Y, Shimizu, T, Kusumoto, M, Kyogoku, Y, Taniguchi, T, Hakoshima, T. | 登録日 | 1999-05-30 | 公開日 | 1999-10-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. EMBO J., 18, 1999
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2EMT
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![BU of 2emt by Molmil](/molmil-images/mine/2emt) | Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1 | 分子名称: | P-selectin glycoprotein ligand 1, Radixin | 著者 | Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T. | 登録日 | 2007-03-28 | 公開日 | 2008-03-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of PSGL-1 binding to ERM proteins Genes Cells, 12, 2007
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5YIZ
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5YJ0
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5YJ1
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![BU of 5yj1 by Molmil](/molmil-images/mine/5yj1) | Mouse Cereblon thalidomide binding domain complexed with R-form thalidomide | 分子名称: | 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione, Protein cereblon, SULFATE ION, ... | 著者 | Mori, T, Hakoshima, T. | 登録日 | 2017-10-06 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of thalidomide enantiomer binding to cereblon Sci Rep, 8, 2018
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5B3G
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![BU of 5b3g by Molmil](/molmil-images/mine/5b3g) | The crystal structure of the heterodimer of SHORT-ROOT and SCARECROW GRAS domains | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | 著者 | Hirano, Y, Nakagawa, M, Hakoshima, T. | 登録日 | 2016-02-29 | 公開日 | 2017-03-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD Nat Plants, 3, 2017
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6K3C
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![BU of 6k3c by Molmil](/molmil-images/mine/6k3c) | Crystal structure of class I PHA synthase (PhaC) mutant from Chromobacterium sp. USM2 bound to Coenzyme A. | 分子名称: | COENZYME A, Intracellular polyhydroxyalkanoate synthase | 著者 | Chek, M.F, Kim, S.Y, Mori, T, Hakoshima, T. | 登録日 | 2019-05-17 | 公開日 | 2020-04-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.074 Å) | 主引用文献 | Asymmetric Open-Closed Dimer Mechanism of Polyhydroxyalkanoate Synthase PhaC. Iscience, 23, 2020
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6L0V
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![BU of 6l0v by Molmil](/molmil-images/mine/6l0v) | Structure of RLD2 BRX domain bound to LZY3 CCL motif | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NGR2, ... | 著者 | Hirano, Y, Futrutani, M, Nishimura, T, Taniguchi, M, Morita, M.T, Hakoshima, T. | 登録日 | 2019-09-27 | 公開日 | 2020-02-05 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.347 Å) | 主引用文献 | Polar recruitment of RLD by LAZY1-like protein during gravity signaling in root branch angle control. Nat Commun, 11, 2020
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3AU4
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2RRD
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![BU of 2rrd by Molmil](/molmil-images/mine/2rrd) | Structure of HRDC domain from human Bloom syndrome protein, BLM | 分子名称: | HRDC domain from Bloom syndrome protein | 著者 | Sato, A, Mishima, M, Nagai, A, Kim, S.Y, Ito, Y, Hakoshima, T, Jee, J.G, Kitano, K. | 登録日 | 2010-07-19 | 公開日 | 2010-09-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the HRDC domain of human Bloom syndrome protein BLM J.Biochem., 148, 2010
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1ISN
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![BU of 1isn by Molmil](/molmil-images/mine/1isn) | Crystal structure of merlin FERM domain | 分子名称: | merlin | 著者 | Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T. | 登録日 | 2001-12-13 | 公開日 | 2002-04-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain. J.Biol.Chem., 277, 2002
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1RLS
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![BU of 1rls by Molmil](/molmil-images/mine/1rls) | CRYSTAL STRUCTURE OF RNASE T1 COMPLEXED WITH THE PRODUCT NUCLEOTIDE 3'-GMP. STRUCTURAL EVIDENCE FOR DIRECT INTERACTION OF HISTIDINE 40 AND GLUTAMIC ACID 58 WITH THE 2'-HYDROXYL GROUP OF RIBOSE | 分子名称: | CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 | 著者 | Gohda, K, Oka, K.-I, Tomita, K.-I, Hakoshima, T. | 登録日 | 1994-03-29 | 公開日 | 1994-12-20 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of RNase T1 complexed with the product nucleotide 3'-GMP. Structural evidence for direct interaction of histidine 40 and glutamic acid 58 with the 2'-hydroxyl group of the ribose. J.Biol.Chem., 269, 1994
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6KPD
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6KPB
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2E3H
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![BU of 2e3h by Molmil](/molmil-images/mine/2e3h) | |