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2G5F
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BU of 2g5f by Molmil
The structure of MbtI from Mycobacterium Tuberculosis, the first enzyme in the synthesis of Mycobactin, reveals it to be a salicylate synthase
分子名称: COG0147: Anthranilate/para-aminobenzoate synthases component I, GLYCEROL, IMIDAZOLE, ...
著者Harrison, A.J, Lott, J.S, Yu, M, Ramsay, R, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
登録日2006-02-22
公開日2006-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase
J.Bacteriol., 188, 2006
2RFX
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BU of 2rfx by Molmil
Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Archbold, J.K, Macdonald, W.A, Rossjohn, J, McCluskey, J.
登録日2007-10-02
公開日2008-07-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity
Immunity, 28, 2008
3DPD
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BU of 3dpd by Molmil
Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-Dihydro-2H-benzo[1,4]oxazines
分子名称: 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者Ceska, T.A.
登録日2008-07-08
公開日2008-08-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines
Bioorg.Med.Chem.Lett., 18, 2008
3CGO
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BU of 3cgo by Molmil
IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding
分子名称: 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide, Mitogen-activated protein kinase 10
著者Ceska, T.A, Platt, A, Fortunato, M, Dickson, K.M, Beevers, R.
登録日2008-03-06
公開日2008-06-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding
Bioorg.Med.Chem.Lett., 18, 2008
3CGF
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BU of 3cgf by Molmil
IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding
分子名称: Mitogen-activated protein kinase 10, N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine
著者Ceska, T.A, Platt, A, Fortunato, M, Dickson, K.M, Buckley, G.
登録日2008-03-05
公開日2008-06-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding
Bioorg.Med.Chem.Lett., 18, 2008
4H80
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BU of 4h80 by Molmil
Crystal structure of human ALDH3A1 with its isozyme selective inhibitor - N-[4-(4-methylsulfonyl-2-nitroanilino)phenyl]acetamide
分子名称: Aldehyde dehydrogenase, dimeric NADP-preferring, N-(4-{[4-(methylsulfonyl)-2-nitrophenyl]amino}phenyl)acetamide
著者Hurley, T.D, Parajuli, B.
登録日2012-09-21
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Kinetic and Structural Characterization of a Selective Inhibitor for Human ALDH3A1
To be Published
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件を2024-07-31に公開中

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